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The protein encoded by CTNNBIP1 binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. Additionally we are shipping CTNNBIP1 Proteins (17) and CTNNBIP1 Kits (4) and many more products for this protein.
Showing 10 out of 38 products:
Human Polyclonal CTNNBIP1 Primary Antibody for IF (p), IHC (p) - ABIN753748
Qi, Chen, Cheng, Huang, Xiang, Li, Long, Zhu: Targeting the Wnt-Regulatory Protein CTNNBIP1 by micro RNA-214 Enhances the Stemness and Self-Renewal of Cancer Stem-Like Cells in Lung Adenocarcinomas. in Stem cells (Dayton, Ohio) 2015
miR (show MLXIP Antibodies)-29b plays a pivotal role in fetal mouse neurogenesis by regulating ICAT-mediated Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.
Mechanistic studies revealed that CTNNBIP1 suppresses Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling and that miR (show MLXIP Antibodies)-215 promotes beta-catenin (show CTNNB1 Antibodies) activation and upregulates alpha-SMA (show SMN1 Antibodies) and fibronectin (show FN1 Antibodies) expression in TGF-beta1 (show TGFB1 Antibodies)-treated MMCs by targeting CTNNBIP1
Overexpression of Icat induces G(2) arrest and cell death in tumor cell mutants for adenomatous polyposis coli (show APC Antibodies), beta-catenin (show CTNNB1 Antibodies), or Axin (show AXIN1 Antibodies).
ICAT plays an important role in the anteriorization of neural cells by inhibiting the posteriorizing activity of Wnt (show WNT2 Antibodies) signaling
These results suggest that the loss of ICAT gene function causes the arrest of UB branching and the apoptotic death of MM cells, resulting in renal agenesis.
Inhibition of beta-catenin (show CTNNB1 Antibodies) signaling in articular chondrocytes causes increased cell apoptosis and articular cartilage destruction in Col2a1 (show COL2A1 Antibodies)-ICAT- transgenic mice.
Data show that microRNA miR (show MLXIP Antibodies)-215 activates beta-catenin (show CTNNB1 Antibodies) pathways by decreasing catenin beta interacting protein 1 (CTNNBIP1)expression in gliomas.
Simultaneous silencing of beta-catenin (show CTNNB1 Antibodies) and STAT3 (show STAT3 Antibodies) synergistically induces apoptosis and inhibits cell proliferation in HepG2 liver cancer cells.
Finally, pro-incubation with idebenone inhibited mitochondrial dysfunction induced by oxLDL through the mitochondrial-dependent apoptotic pathway and GSK3beta (show GSK3b Antibodies)/beta-catenin (show CTNNB1 Antibodies) signalling pathways.
A potent beta-catenin (show CTNNB1 Antibodies) inhibitor, ICAT/CTNNBIP1 was a direct target of miR (show MLXIP Antibodies)-424-5p.
Particulate matter (PM10) downregulates E-Cadherin (show CDH1 Antibodies)/beta-Catenin (show CTNNB1 Antibodies) expression.
A statistically significant lapatinib- and gefitinib-induced repression of cyclin D1 (show CCND1 Antibodies), MMP9 (show MMP9 Antibodies) and beta-catenin (show CTNNB1 Antibodies) in CERV196 cells.
Nuclear YAP (show YAP1 Antibodies) and cytoplasmic beta-catenin (show CTNNB1 Antibodies) play important roles in carcinogenesis.
miR (show MLXIP Antibodies)-603 regulates glioma development via Wnt (show WNT2 Antibodies)-beta-cateninn signaling pathway and its WIF1 (show WIF1 Antibodies) and CTNNBIP1 targets.
These results indicate that beta-catenin translation is initiated via the IRES and this is regulated by PTX, suggesting that regulation of the IRES-dependent translation of beta-catenin may be involved in the cancer cell response to PTX treatment.
ICAT may serve as a tumor-suppressor in human glioma.
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
, beta-catenin-interacting protein 1
, catenin, beta interacting protein 1 a
, catenin beta interacting protein 1 b
, catenin, beta interacting protein 1
, inhibitor of beta-catenin and Tcf-4
, beta-catenin-interacting protein ICAT