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May be involved in formation of stretch-resistant cell- cell adhesion complexes (By similarity).. Additionally we are shipping CTNNA3 Antibodies (63) and many more products for this protein.
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AlphaT-catenin may contribute to asthma through a mechanism independent of inflammation and related to heart and pulmonary vein dysfunction.
alphaT-catenin-null mice are viable and fertile; however, the animals exhibit progressive cardiomyopathy
study suggests a pivotal role of alphaT-catenin levels in the control of the proliferative versus invasive state of trophoblasts during placentation
By providing an extra link between the cadherin-catenin complex and intermediate filaments, the binding of alphaT-catenin to plakophilin-2 is proposed to be a means of modulating and strengthening cell-cell adhesion between cardiac muscle cells.
Loss of CTNNA3 expression is associated with hepatocellular carcinoma.
Among the genes replicated across the two samples (permutated p < 0.05 in both of them), CTNNA3 appeared promising. The inorganic cation transmembrane transporter activity pathway (GO:0022890) was associated with antidepressant response in both samples (p = 2.9e-5 and p = 0.001 in the Korean and STAR*D samples, respectively)
Two African-ancestry specific variants were found to be significantly associated with metabolic syndrome S: SNP rs73989312[A] near CA10 (show CA10 Proteins) that conferred increased risk; and SNP rs77244975[C] in CTNNA3 that conferred protection against this disease.
CTNNA3 and SEMA3D (show SEMA3D Proteins): Promising loci for asthma exacerbation identified through multiple genome-wide association studies
This study demonstrated that the copy number variations of CTNNA3 relate to opioid dependence.
Copy Number Variations in CTNNA3 and RBFOX1 (show A2BP1 Proteins) Associate with Pediatric Food Allergy
Significant interaction with maternal CMV infection was found for rs7902091 (PSNP x CMV=7.3 x 10-7) in CTNNA3, a gene not previously implicated in schizophrenia.
These results suggest aberrant Claudin 7 (show CLDN7 Proteins), alpha - and beta-catenin (show CTNNB1 Proteins) expression and/or localisation patterns may be putative markers for distinguishing localised prostate cancer from aggressive metastatic disease when used collectively.
CTNNA2 (show CTNNA2 Proteins) and CTNNA3 are tumor suppressor genes frequently mutated in laryngeal carcinomas.
CTNNA3 is not major contributor or genetic risk factor for childhood asthma but rather influence the disease expression and response to therapy.
May be involved in formation of stretch-resistant cell- cell adhesion complexes (By similarity).
catenin, alpha 3
, catenin alpha-3
, catenin (cadherin-associated protein), alpha 3
, alpha T-catenin
, alpha-catenin-like protein
, cadherin-associated protein
, catenin alpha 3