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anti-Cathepsin B (CTSB) Antibodies

The protein encoded by CTSB is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally we are shipping Cathepsin B Kits (66) and Cathepsin B Proteins (47) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CTSB 1508 P07858
CTSB 13030 P10605
CTSB 64529  
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Top anti-Cathepsin B Antibodies at

Showing 10 out of 150 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC, WB Western blot analysis of Cathepsin B with Jurkat cell (Lane 1) and mou... 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Ant... Formalin-fixed and paraffin embedded human esophageal carcinoma tissue... 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IP, ELISA, WB 100 μg Log in to see 16 Days
Human Rabbit Un-conjugated WB Anti-Cathepsin B Picoband antibody,  All lanes: Anti-Cathepsin B at 0.... 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated WB Western blot analysis of Cathepsin B expression in SW480 (A) whole cel... 200 μL Log in to see 9 Days
Human Rabbit Un-conjugated IHC (p), WB Human Thyroid (formalin-fixed, paraffin-embedded) stained with CTSB an... Human Liver (formalin-fixed, paraffin-embedded) stained with CTSB anti... 50 μg Log in to see 8 to 10 Days
Human Mouse Un-conjugated IHC (p)   1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days

CTSB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Cathepsin B Antibodies

  1. Human Polyclonal Cathepsin B Primary Antibody for FACS, IHC - ABIN222979 : Rybicka, Balce, Chaudhuri, Allan, Yates: Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner. in The EMBO journal 2012 (PubMed)
    Show all 3 references for ABIN222979

  2. Human Polyclonal Cathepsin B Primary Antibody for IP, ELISA - ABIN1996943 : Gogiel, Wola?ska, Galewska, Kinalski, Sobolewski, Romanowicz: Cathepsin B in human myometrium and in uterine leiomyomas at various stages of tumour growth. in European journal of obstetrics, gynecology, and reproductive biology 2015 (PubMed)

  3. Human Polyclonal Cathepsin B Primary Antibody for IF (p), IHC (p) - ABIN687412 : Liu, Tang, Zhang, Li, Yuan, Wang: Autophagy activation aggravates neuronal injury in the hippocampus of vascular dementia rats. in Neural regeneration research 2014 (PubMed)

More Antibodies against Cathepsin B Interaction Partners

Silk Worm Cathepsin B (CTSB) interaction partners

  1. Cathepsin B is involved in the programmed cell death of the fat body during B. mori metamorphosis, and that cathepsin B and cathepsin B contribute to B (show TDO2 Antibodies). mori metamorphosis.

Human Cathepsin B (CTSB) interaction partners

  1. Cathepsin B knockdown in oral cancer cells reduces cell migration.

  2. the authors applied the technique of nanoelectrode arrays to try to detect and compare cathepsin B activities in normal and breast cancer cells. It was found that protease activity correlated positively with the degree of malignancy cancer cells.

  3. shedding of surface proteins by extracellular cathepsins impacts intracellular signaling as demonstrated for regulation of Ras GTPase (show RACGAP1 Antibodies) activity.

  4. High cathepsin is associated with drug resistance in neuroblastoma (show ARHGEF16 Antibodies).

  5. The expressions of cathepsin B strongly correlated with the Mini-Mental State Examination scores of the Alzheimer disease. patients

  6. Integrin alphavbeta3 (show ITGAV Antibodies) is required for cathepsin B-induced hepatocellular carcinoma progression

  7. The serum level of cathepsin L (show CTSL1 Antibodies) decreased with age, while cathepsin B remained no significant difference between young and aged individuals

  8. enhanced activity and expression of cathepsin B contributes to an increased remodelling of extracellular matrix that favours leiomyoma growth

  9. SCD5 (show SCD5 Antibodies) impairs SPARC (show SPARC Antibodies) and cathepsin B secretion in human melanoma cells and intracellular pH acidification.

  10. data suggest that CTSB is a pathophysiologically relevant protease that activates ENaC (show SCNN1A Antibodies) in cystic fibrosis (show S100A8 Antibodies) airways

Mouse (Murine) Cathepsin B (CTSB) interaction partners

  1. Aggregatibacter actinomycetemcomitans invasion of macrophages induces interleukin-1beta production through reactive oxygen species and cathepsin B.

  2. Findings indicate that Ctsb-/- BMDC display more pro-Th1 (show HAND1 Antibodies) properties than their WT and Ctsl (show CTSL1 Antibodies)-/- counterparts, and therefore suggest that Ctsb down-regulates the Th1 (show HAND1 Antibodies) response to L. major.

  3. Cathepsin B showed the highest protein levels in the anterior segments of the gastrointestinal tract, whereas the highest activity was observed in the jejunum

  4. CtsB and CtsL (show CTSL1 Antibodies) are essential in alpha-syn lysosomal degradation

  5. Reactive oxygen species and cathepsin B activities are necessary for maximal iNOS (show NOS2 Antibodies) induction in C. muridarum-infected macrophages.

  6. CTSB protein functions as a necessary modulator of hypertrophic response by regulating TNF-alpha (show TNF Antibodies)/ASK1 (show MAP3K5 Antibodies)/JNK (show MAPK8 Antibodies) signaling pathway involved in cardiac remodeling.

  7. Abeta (show APP Antibodies) oligomers, but not fibrils, induce IL-1beta (show IL1B Antibodies) production in primary microglia in a cathepsin B- and reactive oxygen species -dependent manner.

  8. Cathepsin B produces full-length amyloid-beta (Ab(1-40/42)) and pyroglutamate amyloid-beta (pyroGluAb(3-40/42) and is a key drug target for treating Alzheimer's disease by reducing these amyloid-beta species

  9. cysteine cathepsins B and S can directly cleave Rip1 (show RALBP1 Antibodies)

  10. these results support a causative role of VEGF in perinatal cerebral hemorrhage and implicate its downstream proteases as potential therapeutic targets.

Cow (Bovine) Cathepsin B (CTSB) interaction partners

  1. The cathepsin B deserves further evaluation as therapeutic targets to develop disease modifying drugs to treat Alzheimer's disease.

  2. evidence shows cathepsin B activity may not be redox regulated; however, the stability of the enzyme at neutral pH is dependent on redox potential, and on the presence of oxidising agents.

  3. Overexpressing cathepsin B reduced the Vascular Endothelial Growth Factor-dependent tube response

  4. The peptides, all of which contain a C-terminal free acid, were tested as inactivators of bovine cathepsin B, in an attempt at exploiting the known and, amongst the cysteine proteinases, unique carboxy dipeptidyl peptidase (show ACE Antibodies) activity of the protease.

Pig (Porcine) Cathepsin B (CTSB) interaction partners

  1. Findings showed that CTSB facilitates adipogenesis, and its effect is associated with fibronectin degradation and Wnt/b-catenin signaling pathway.

  2. CTSB may be required to remodel endometrial and placental tissues for close apposition between maternal and fetal vasculatures and to facilitate transplacental transport of gases, micronutrients (amino acids, glucose), and macromolecules (proteins).

Cathepsin B (CTSB) Antigen Profile

Protein Summary

The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with anti-Cathepsin B (CTSB) Antibodies

  • cathepsin B (ctsb) antibody
  • cathepsin B (LOC692390) antibody
  • cathepsin B (Catb-2744) antibody
  • cathepsin B-1674 (Catb-1674) antibody
  • cathepsin B-84 (Catb-84) antibody
  • cathepsin B-3098 (Catb-3098) antibody
  • cathepsin B-16D2 (Catb-16d2) antibody
  • cathepsin B-1874 (Catb-1874) antibody
  • cathepsin B-3483 (Catb-3483) antibody
  • cathepsin B-10270 (Catb-10270) antibody
  • cathepsin B (CTSB) antibody
  • cathepsin B (Ctsb) antibody
  • cathepsin B (LOC100101593) antibody
  • ACYPI000009 antibody
  • ACYPI000014 antibody
  • ACYPI000017 antibody
  • ACYPI000018 antibody
  • ACYPI000019 antibody
  • ACYPI000020 antibody
  • ACYPI000021 antibody
  • APPS antibody
  • catb-16D antibody
  • Catb-16d2 antibody
  • Catb-84 antibody
  • catb-1674a antibody
  • Catb-1874 antibody
  • Catb-2744 antibody
  • Catb-3098 antibody
  • Catb-3483 antibody
  • Catb-10270 antibody
  • CB antibody
  • CPSB antibody
  • CTSB antibody
  • LOC692390 antibody

Protein level used designations for anti-Cathepsin B (CTSB) Antibodies

cathepsin B , cathepsin B-2744 , cathepsin B-1674 , cathepsin B-84 , cathepsin B-3098 , cathepsin B-16D2 , cathepsin B-1874 , cathepsin B-3483 , cathepsin B-10270 , APP secretase , amyloid precursor protein secretase , cathepsin B1 , cysteine protease , RSG-2 , BCSB

379257 Xenopus laevis
692390 Bombyx mori
100144781 Acyrthosiphon pisum
100144784 Acyrthosiphon pisum
100144787 Acyrthosiphon pisum
100144790 Acyrthosiphon pisum
100144791 Acyrthosiphon pisum
100144794 Acyrthosiphon pisum
100144795 Acyrthosiphon pisum
100144796 Acyrthosiphon pisum
100424758 Macaca mulatta
463993 Pan troglodytes
1508 Homo sapiens
13030 Mus musculus
64529 Rattus norvegicus
281105 Bos taurus
396329 Gallus gallus
100037961 Sus scrofa
780470 Ovis aries
100101593 Oryctolagus cuniculus
100173564 Pongo abelii
Selected quality suppliers for anti-Cathepsin B (CTSB) Antibodies
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