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Cathepsin L2 Proteins (CTSL2)

The protein encoded by CTSL2, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. Additionally we are shipping Cathepsin L2 Antibodies (64) and Cathepsin L2 Kits (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CTSL2 1515 O60911
CTSL2 281108 P25975
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Top Cathepsin L2 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$750.20
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,552.00
Details
HOST_HEK-293 Cells Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details
HOST_Human Human Un-conjugated   10 μg Log in to see 11 to 14 Days
$345.35
Details

CTSL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Cow (Bovine)

Top referenced Cathepsin L2 Proteins

  1. Human Cathepsin L2 Protein expressed in Human Cells - ABIN2002043 : Puzer, Barros, Paschoalin, Hirata, Tanaka, Oliveira, Brömme, Carmona: Cathepsin V, but not cathepsins L, B and K, may release angiostatin-like fragments from plasminogen. in Biological chemistry 2008 (PubMed)

More Proteins for Cathepsin L2 (CTSL2) Interaction Partners

Cow (Bovine) Cathepsin L2 (CTSL2) interaction partners

  1. The cathepsin L (show CTSL Proteins) deserves further evaluation as therapeutic targets to develop disease modifying drugs to treat Alzheimer's disease.

  2. Cathepsin L (show CTSL Proteins) has an previously uncharacterized biological role in the production of [Met]enkephalin, an endogenous peptide neurotransmitter

  3. Secretory vesicle function of cathepsin L (show CTSL Proteins) for biosynthesis of active enkephalin opioid peptide contrasts with its function in lysosomes for protein degradation.

Human Cathepsin L2 (CTSL2) interaction partners

  1. E2F1 (show E2F1 Proteins) directly binds to CTSL2 promoter and regulates CTSL2 gene expression.

  2. using cathepsin V and cathepsin L (show CTSL1 Proteins) as model enzymes, a series of chimeras were generated to identify noncatalytic regions that are responsible for the potent elastolytic activity of cathepsin V

  3. inflammatory cues and monocyte-endothelial cell interactions upregulate cathepsin K (show CTSK Proteins) and V activity via a JNK (show MAPK8 Proteins) signaling axis

  4. Findings indicate the unique function of cathepsin V for producing enkephalin and neuropeptide Y (NPY (show NPY Proteins)) neuropeptides required for neurotransmission in health and neurological diseases.

  5. CTSL2 might be involved in progression of endometrial cancer.

  6. functions of CTSL (show CTSL1 Proteins) and CTSV in the positive selection of CD4 (show CD4 Proteins)+ T cells

  7. A proteolytically active variant of cathepsin V is localized to cell nucleus (in peri (show PLIN1 Proteins)-nucleolar pattern) in thyroid carcinoma cells.

  8. stratum corneum thiol protease is identical with the recently described cathepsin L2 protease.

  9. Human cathepsin V compensates for murine cathepsin L (show CTSL1 Proteins) in mouse epidermis and hair follicles.

  10. Identification of CTSV & CTSL (show CTSL1 Proteins) as targets for cystatin M/E (show CST6 Proteins), their (co)-expression in the stratum granulosum of skin, and activity of CTSL (show CTSL1 Proteins) toward transglutaminase 3 (show TGM3 Proteins) strongly imply an important role for them in the differentiation process of human epidermis.

Cathepsin L2 (CTSL2) Protein Profile

Protein Summary

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with Cathepsin L2 Proteins (CTSL2)

  • cathepsin L2 (CTSL2)
  • cathepsin V (ctsv)
  • cathepsin L2 (LOC100232421)
  • cathepsin V (CTSV)
  • CATL2 protein
  • CCL protein
  • CTSL protein
  • CTSL1 protein
  • ctsl2 protein
  • CTSU protein
  • LOC100232421 protein

Protein level used designations for Cathepsin L2 Proteins (CTSL2)

cathepsin L2 , cathepsin L , cathepsin L1 , cathepsin L2 preproprotein , cathepsin L2, preproprotein , cathepsin U

GENE ID SPECIES
403708 Canis lupus familiaris
447313 Xenopus laevis
448179 Xenopus (Silurana) tropicalis
464593 Pan troglodytes
710850 Macaca mulatta
780510 Ovis aries
100232421 Taeniopygia guttata
100439744 Pongo abelii
281108 Bos taurus
1515 Homo sapiens
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