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The scaffolding protein encoded by CAV1 is the main component of the caveolae plasma membranes found in most cell types. Additionally we are shipping Caveolin-1 Antibodies (307) and Caveolin-1 Kits (73) and many more products for this protein.
Showing 10 out of 33 products:
Human Caveolin-1 Protein expressed in Wheat germ - ABIN1348146
Kastelijn, van Moorsel, Kazemier, Roothaan, Ruven, Kwakkel-van Erp, van de Graaf, Zanen, van Kessel, Grutters: A genetic polymorphism in the CAV1 gene associates with the development of bronchiolitis obliterans syndrome after lung transplantation. in Fibrogenesis & tissue repair 2011
Show all 4 references for ABIN1348146
Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration.
The development of transgenic zebrafish lines expressing CLTA (show CLTA Proteins) fused to dsRed and CAV1 fused to GFP is reported.
maternally expressed zebrafish Cav-1 regulates dorsoventral patterning by limiting nuclear translocation of active beta-catenin (show CTNNB1 Proteins)
These results support important and previously unanticipated roles for the Caveolin-1 isoforms in vertebrate organogenesis.
interactions of cav1 at lipid-exposed domains regulate the partition of the receptor into membrane raft microdomains
In vitro caveolin-1 silencing decreased the chondrocyte-like cell microaggregate glycosaminoglycan (GAG) content
The results suggest that caveolin-1/TLR5 (show TLR5 Proteins) signaling plays a key role in age-associated innate immune responses and that FlaB (show FliC Proteins)-PspA (show SFTPA1 Proteins) stimulation of TLR5 (show TLR5 Proteins) may be a new strategy for a mucosal vaccine adjuvant against pneumococcal infection in the elderly.
Cav-1 has a novel role in TCR/Lck spatial distribution upon TCR triggering, which controls T-cell fate toward a regulatory phenotype
Data show that caveolin 1 (CAV1) is required for transforming growth factor-beta (TGF-beta)-induced reactive oxygen species production, mediated by NADPH oxidase (show NOX1 Proteins) NOX1 (show NOX1 Proteins), that is necessary for a disintegrin and metalloproteinase 17 (ADAM17 (show ADAM17 Proteins)) activation.
physiologic adiponectin (show ADIPOQ Proteins) levels enhance the vasorelaxative response to acetylcholine by inducing nitric oxide production through AdipoR1 (show ADIPOR1 Proteins)/Cav-1 mediated signaling.
results demonstrate that alterations in lipid rafts by the loss of parkin (show PARK2 Proteins) via cav-1 may be a causal factor of parties of disease
Cav-1-dependent c-Fms (show CSF1R Proteins) stabilization contributes to efficient osteoclastogenesis.
A novel role for intracellular caveolin-1 in modulating phagolysosomal function.
These data indicate that oxygen-glucose deprivation-triggered Cav-1 S-nitrosylation interacts with tPA (show PLAT Proteins)-induced ERK (show EPHB2 Proteins) activation to augment MMP2 (show MMP2 Proteins) and 9 secretion and subsequent extracellular matrix degradation.
Cav-1-induced MMP9 (show MMP9 Proteins) is exclusively involved in inward remodeling, not hypertrophy.
Data show that the CAV1 K176R mutant blocks the interaction with P-glycoprotein and abolishes the inhibition of P-glycoprotein by CAV1. These effects contribute to the understanding of the regulation of P-glycoprotein and drug resistance in cancer cells.
Decreased expression of Cav-1 and E-cadherin (show CDH1 Proteins) plays a role in the progression of gastric cancer.
lower serum Cav-1 levels may be associated with cerebral microbleeds, especially those that are multiple and located in deep brain or infratentorial structures, in patients with acute ischemic stroke.
We identified potential nuclear and membrane biomarkers (increased expression of ZO-1 (show TJP1 Proteins), caveolin-1 and P2X7 receptor (show P2RX7 Proteins)) of risks for placenta and pregnancy
rs3807989 at the CAV1/CAV2 (show CAV2 Proteins) locus was associated with significant risk of coronary artery disease and myocardial infarction by increasing expression of CAV1 (but not CAV2 (show CAV2 Proteins)).
Data indicate that the caveolin-1 (CAV1) control on dopachrome tautomerase (DCT (show DCT Proteins)) gene expression, DCT (show DCT Proteins) post-translational processing, and subcellular distribution is cell phenotype-dependent.
Data indicate that knockdown of caveolin-1 (Cav-1) expression causes redistribution of the P2Y2 nucleotide receptor (P2Y2R (show P2RY2 Proteins)) from membrane rafts.
Decreased caveolin-1 expression is associated with increased expression and phosphorylation levels of eNOS (show NOS3 Proteins) in endothelial cells stimulated by microgravity, which causes a dissociation of eNOS (show NOS3 Proteins) from caveolin-1 complexes.
Data show that caveolin-1 (Cav-1) expression in MCF7 breast cancer epithelial cells represses NF-E2-related factor 2 (Nrf2 (show NFE2L2 Proteins)) and superoxide dismutase (MnSOD (show SOD2 Proteins)).
Cav-1 may regulate the hepatocyte-like differentiation of human adipose-derived stem cellsby modulating mitogen-activated protein kinase kinase (show MAP2K1 Proteins)/MAPK (show MAPK1 Proteins) signaling.
Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer
transcription factor Sp1 (show SP1 Proteins) interacts with nucleotides -123/-114, indicating that Sp1 (show SP1 Proteins) could play a key role in the transcriptional regulation of pig CAV-1
Two alternative transcript variants encode two isoforms, caveolin-1-alpha and -beta; Cav1 may be implicated in pathogenesis of Glasser's disease of swine.
The plasma membrane Na/K-ATPase (show ATP1A1 Proteins)-caveolin-1 interaction may represent an important sensing mechanism by which the cells regulate the sterol regulatory element-binding protein (show CNBP Proteins) pathway.
The present study indicates that caveolin-containing rafts/caveolins such as caveolin-1 could play a modulating role during oligodendroglial differentiation and regeneration via NGF (show NGFB Proteins)/TrkA (show NTRK1 Proteins) signaling.
Cav-1 might be a candidate gene for carcass traits, and might provide valuable information for understanding the mechanism of caveolae signaling in fat deposition by using the animal model of pig
8-Bromo-cAMP stimulated alpha-methyl-D-glucopyranoside uptake via Epac and PKA-dependent SGLTs expression and trafficking through cav-1 and F-actin in proximal tubule cells.
Caveolin-1 scaffolding domain residue phenylalanine 92 modulates Akt (show AKT1 Proteins) signaling
Data show that resveratrol (Res) reversed caveolin-1 (Cav-1)/endothelial nitric oxide synthase (eNOS (show NOS3 Proteins)) expressions in high glucose cultured bovine aortic endothelial cells (BAECs).
these data provide the first detailed analysis of Cav-1 binding to one of its most significant client proteins, eNOS (show NOS3 Proteins).
Study identifies a critical role of caveolin-1 in the regulation of eNOS (show NOS3 Proteins) uncoupling via a biopterin-dependent mechanism.
Data indicate that caveolin-1 expression is required for insulin (show INS Proteins) uptake by aortic endothelial cells.
caveolin-1 is not required for the targeting of signaling molecules to caveolae/lipid rafts
integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk (show CSK Proteins) association at integrin sites, where it plays a role in downstream, shear-stimulated myelin light chain diphosphorylation.
importance of CAV1 amino acids 89-95 and particularly F92 in mediating eNOS (show NOS3 Proteins) inhibition by AP-Cav and Cav-1
When endothelial cells were exposed to shear stress, caveolin-1 was transiently dephosphorylated.
caveolin-1 tyrosine 14 phosphorylation has a role in cell adhesion and migration
results suggest that cell division control protein 42(CDC42 (show CDC42 Proteins)) activation is favored by the disruption of the caveolin-1-CDC42 (show CDC42 Proteins) interaction, allowing for its participation in the regulation of capacitation and the acrosome reaction
The distribution of CAV-1 is highly dynamic during development and provides new insights into the sorting mechanisms that regulate CAV-1 localization.
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
, caveolin 1
, caveolin, caveolae protein 1
, caveolin, caveolae protein, 22 kDa
, caveolin caveolae protein 22 kDa
, vesicular integral-membrane protein VIP21
, cell growth-inhibiting protein 32
, testis derived transcript