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CITED1 encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. Additionally we are shipping CITED1 Kits (12) and CITED1 Proteins (8) and many more products for this protein.
Showing 10 out of 55 products:
Cow (Bovine) Polyclonal CITED1 Primary Antibody for IHC, WB - ABIN2777537
Fenner, Parrish, Boyd, Reed, MacDonald, Nelson, Isselbacher, Shioda: MSG1 (melanocyte-specific gene 1): mapping to chromosome Xq13.1, genomic organization, and promoter analysis. in Genomics 1998
Dicer (show DICER1 Antibodies) ablation in the early metanephric mesenchyme results in severe renal dysgenesis despite normal initial specification of nephron progenitors and ureteric bud outgrowth.
The data indicated that serine phosphorylation at position 79 in the 63-84 domain is associated with PKC (show PKC Antibodies) activation, and is required for both CITED1 nuclear translocation induced by PTH (show PTH Antibodies)
Loss of placental Cited1 leads to intrauterine organ growth restriction with decreased IGF-I (show IGF1 Antibodies) and IGF-II expression and in IR and Igf1r (show IGF1R Antibodies) signaling.
CBP (show CREBBP Antibodies) inactivation in mouse thymocytes leads to lymphoma
role for CITED1 in the modulation of transcriptional events mediated by steroid hormone and cytokine signaling pathways
The expression pattern of Cited2 (show CITED2 Antibodies) overlaps that of Cited1, but its deletion, either alone or in combination with Cited1, does not disrupt epithelial differentiation of the metanephric mesenchyme.
These observations suggest that, in addition to an increased gene copy number and upregulation of EGR2 (show EGR2 Antibodies) and CITED1, an elevated erbB2 (show ERBB2 Antibodies) transcript level involves the loss of 14-3-3sigma, which sequesters a key transcriptional regulator of the erbB2 (show ERBB2 Antibodies) promoter.
CITED1 negatively regulates osteoblastic differentiation in vitro and inhibits the cAMP-dependent stimulation of differentiation by intermittent PTH (show PTH Antibodies).
Renal medullary dysplasia in Cited1 mutant mice is a direct consequence of decreased tissue oxygenation resulting from placental insufficiency.
Forced nuclear enrichment of CITED1 in a human WT cell line appears to enhance tumorigenicity, whereas ectopic cytosolic expression confers stem-like properties and an embryonic phenotype.
Thus deficiency of Cited1 leads to hyper-activation of Wnt (show WNT2 Antibodies) signaling and an exaggerated Wnt (show WNT2 Antibodies) phenotype including elevated cell death
The CITED1 expression is correlated with lymph node metastasis in patients with colorectal cancer.
CITED1 expression remains active across all disease characteristics of Wilms tumor. It is found in the nucleus & cytosol. It is not found in normal kidney.
epigenetic regulation is involved in the overexpression of CITED1 in papillary thyroid cancer
TOX3 (show TOX3 Antibodies) induces transcription in neuron depending on the presence of CITED1 or phosphorylated CREB (show CREB1 Antibodies) in the transcriptionally active complex.
CITED1 functions as a cell cycle-dependent transcriptional cofactor whose activity is regulated by phosphorylation
CITED1 could play a role in Wilms' tumor initiation and pathogenesis.
This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described.
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
, similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1)
, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
, cbp/p300-interacting transactivator 1
, melanocyte-specific protein 1
, melanocyte-specific gene 1 protein
, melanocyte-specific gene 1
, transactivator, with Glu/Asp-rich carboxy-terminal domain, 1