You are viewing an incomplete version of our website. Please click to reload the website as full version.

Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 Proteins (CITED2)

The protein encoded by CITED2 inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Additionally we are shipping CITED2 Antibodies (59) and CITED2 Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CITED2 10370 Q99967
CITED2 17684 O35740
Rat CITED2 CITED2 114490  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top CITED2 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,563.00
Details
Yeast Saguinus labiatus His tag   1 mg Log in to see 56 to 66 Days
$2,713.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,713.33
Details
HOST_Escherichia coli (E. coli) Human Biotin   1 mg Log in to see 3 to 4 Days
$3,349.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$534.64
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CITED2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Top referenced CITED2 Proteins

  1. Human CITED2 Protein expressed in Escherichia coli (E. coli) - ABIN666771 : Bijl, Thompson, Ramirez-Solis, Krosl, Grier, Lawrence, Sauvageau: Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells. in Blood 2006 (PubMed)
    Show all 2 references for ABIN666771

More Proteins for Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) Interaction Partners

Human Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) interaction partners

  1. Intrinsic protein disorder plays a prominent role in the function and interactions of the transcriptional co-activators CBP (show CREBBP Proteins) and p300 (show EP300 Proteins). (Review)

  2. FBXL5 (show FBXL5 Proteins)-mediated degradation of CITED2 leads to the activation of HIF-1 alpha (show HIF1A Proteins).

  3. The increased CITED2 expression in acute myeloid leukemia results in better hematopoietic stem cell survival, lower PU.1 levels, and perturbed myeloid differentiation program that contributes to leukemia persistence.

  4. CITED2 has a potential causative impact on congenital heart disease

  5. Our study suggests that CITED2 gene mutations and methylation may play an important role in the development of pediatric congenital heart disease.

  6. data indicate that CITED2 functions as a transcriptional co-activator of ER in breast cancer cells and that its increased expression in tumors may result in estrogen-independent ER activation

  7. CITED2 is a direct effector of PPARgamma (show PPARG Proteins) for tumor suppression.

  8. CITED2 functions as a molecular switch of TGF-alpha (show TGFA Proteins) and TGF-beta (show TGFB1 Proteins)-induced growth control, and MYC (show MYC Proteins)-CITED2 signaling axis provides a new index for predicting clinical outcome.

  9. CITED2 is phosphorylated by MAPK1 (show MAPK3 Proteins) in vitro at T166, and that MAPK1 (show MAPK3 Proteins) activation enhances the coactivation function of CITED2 but not of CITED2-T166N.

  10. We conclude that mutations in CITED2 may be involved in premature ovarian failure pathogenesis.

Mouse (Murine) Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) interaction partners

  1. Study showed a novel function of miR (show MLXIP Proteins)-200b and CITED2 in high glucose-induced unfolded protein response and ER stress, suggesting that miR (show MLXIP Proteins)-200b and CITED2 are critical for ER homeostasis and neural tube defect formation in the developing embryo.

  2. MicroRNAs in the Myocyte Enhancer Factor 2 (MEF2 (show MEF2C Proteins))-regulated Gtl2-Dio3 (show DIO3 Proteins) Noncoding RNA Locus Promote Cardiomyocyte Proliferation by Targeting the Transcriptional Coactivator Cited2.

  3. Cited2 is required for and enhances reprogramming of mouse embryonic fibroblasts to induced pluripotent stem cells.

  4. Cited2 is required for the maintenance of adult hematopoietic stem cell glycolytic metabolism likely through regulating Pdk2 (show PDK2 Proteins), Pdk4 (show PDK4 Proteins), lactate dehydrogenases B and D, and Akt (show AKT1 Proteins) activity.

  5. Cited2 in sinusoidal trophoblast giant cells and syncytiotrophoblasts is likely to have a non-cell autonomous role in patterning of the pericytes associated with the embryonic capillaries.

  6. a deletion of Cited2 in mESCs results in abnormal mitochondrial morphology and impaired glucose metabolism, which correlates with a defective cell fate decision.

  7. CITED2 is phosphorylated by MAPK1 (show MAPK1 Proteins) in vitro at T166, and that MAPK1 (show MAPK1 Proteins) activation enhances the coactivation function of CITED2 but not of CITED2-T166N.

  8. Cited2 controls ESC pluripotency and differentiation via direct regulation of Oct4 (show POU5F1 Proteins) gene expression.

  9. This study demonistrated that loss of hepatic CITED2 function suppresses gluconeogenesis in diabetic mice, suggesting it as a therapeutic target for hyperglycemia

  10. Our results suggest that Cited2 regulates hematopoietic stem cell quiescence through both HIF-1 (show HIF1A Proteins)-dependent and HIF-1 (show HIF1A Proteins)-independent pathways

CITED2 Protein Profile

Protein Summary

The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with CITED2

  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (cited2)
  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (CITED2)
  • similar to Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal (CITED2)
  • Cbp/p300-interacting transactivator 2 (cite2)
  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (LOC100232815)
  • Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (Cited2)
  • AI835299 protein
  • ASD8 protein
  • cite2 protein
  • CITED2 protein
  • ER154-like protein
  • MRG-1 protein
  • Mrg1 protein
  • Msg2 protein
  • P35SRJ protein
  • VSD2 protein
  • zgc:103418 protein

Protein level used designations for CITED2

TNeu124g09.1 , cbp/p300-interacting transactivator 2 , Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 , similar to Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal , Cbp/p300-interacting transactivator 2 , MSG-related protein 1 , MSG1-related gene 1 , melanocyte-specific gene 1-related gene 1 , melanocyte specific gene 2 , cited2/melanocyte specific gene-related gene 1 MRG1

GENE ID SPECIES
407853 Xenopus (Silurana) tropicalis
450024 Danio rerio
463032 Pan troglodytes
707729 Macaca mulatta
100135454 Ovis aries
100196689 Salmo salar
100232815 Taeniopygia guttata
10370 Homo sapiens
484010 Canis lupus familiaris
521378 Bos taurus
17684 Mus musculus
114490 Rattus norvegicus
495124 Xenopus laevis
395399 Gallus gallus
Selected quality suppliers for CITED2 Proteins (CITED2)
Did you look for something else?