You are viewing an incomplete version of our website. Please click to reload the website as full version.

Cdk5 and Abl Enzyme Substrate 1 Proteins (CABLES1)

CABLES1 encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. Additionally we are shipping Cdk5 and Abl Enzyme Substrate 1 Antibodies (23) and Cdk5 and Abl Enzyme Substrate 1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CABLES1 91768 Q8TDN4
CABLES1 63955 Q9ESJ1
Rat CABLES1 CABLES1 307585  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Cdk5 and Abl Enzyme Substrate 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

CABLES1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Cdk5 and Abl Enzyme Substrate 1 (CABLES1) Interaction Partners

Zebrafish Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. cables1 is important for neural differentiation during embryogenesis, in a mechanism that likely involves interactions with the Cdk5 (show CDK5 Proteins)/p35 (show CDK5R1 Proteins) kinase pathway.

Human Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. CABLES1 is a critical regulator of corticotrope proliferation that defines a pathway often inactivated in Cushing disease

  2. the results suggest Cables1 as a novel p21 (show CDKN1A Proteins) regulator through maintaining p21 (show CDKN1A Proteins) stability and support the model that the tumor-suppressive function of Cables1 occurs at least in part through enhancing the tumor-suppressive activity of p21 (show CDKN1A Proteins).

  3. Results illuminated a dynamic regulatory system through which activated Akt (show AKT1 Proteins) and 14-3-3 (show YWHAQ Proteins) work directly together to neutralize a potent tumor suppressor function of Cables1.

  4. The results did not detect a significant association. It indicated that common genetic variations in CDK5 (show CDK5 Proteins) genes might not play a role in the genetic predisposition to autism.

  5. Analysis of the RT-PCR prducts of the CABLES1 gene showed eight intragenic deletions in its mRNA transcripts; 5/8 are the result of RNA splicing.

  6. Mechanisms of CABLES1 gene inactivation in ovarian cancer development are reported.

Mouse (Murine) Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. Loss of Cables1 enhances tumor progression in the Apc (show APC Proteins)(Min/+) mouse model and activates the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway. Cables1 is a tumor suppressor gene on chromosome 18q in this in vivo mouse model.

  2. Agenesis of the corpus callosum frequency in Cables1(+/TAS (show MAP3K4 Proteins)) mice was significantly lower than that in Cables1(-/TAS (show MAP3K4 Proteins)) mice, indicating that wild-type Cables1 interfered with the dominant negative effect of Cables1(TAS (show MAP3K4 Proteins)).

  3. Data show that oocytes lacking Cables1 exhibit lower basal levels of TAp63alpha and reduced accumulation of phosphorylated TAp63alpha in response to genotoxic stress.

  4. Cables1 null mice exhibit a significant expansion of oocyte numbers at the expense of oocyte quality throughout adulthood.

Cdk5 and Abl Enzyme Substrate 1 (CABLES1) Protein Profile

Protein Summary

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CABLES1

  • Cdk5 and Abl enzyme substrate 1 (CABLES1)
  • Cdk5 and Abl enzyme substrate 1 (cables1)
  • Cdk5 and Abl enzyme substrate 1 (CpipJ_CPIJ019832)
  • CDK5 and Abl enzyme substrate 1 (Cables1)
  • Cdk5 and Abl enzyme substrate 1 (Cables1)
  • CABL1 protein
  • Cables protein
  • CABLES1 protein
  • HsT2563 protein
  • ik3-1 protein
  • si:dkey-2p18.3 protein

Protein level used designations for CABLES1

Cdk5 and Abl enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1-like , interactor with CDK3 1 , cdk3-binding protein ik3-1 , interactor-1 with cdk3

GENE ID SPECIES
455335 Pan troglodytes
100059359 Equus caballus
100126070 Danio rerio
100345850 Oryctolagus cuniculus
100479459 Ailuropoda melanoleuca
6054063 Culex quinquefasciatus
100562423 Anolis carolinensis
100603520 Nomascus leucogenys
91768 Homo sapiens
63955 Mus musculus
768914 Gallus gallus
100682687 Canis lupus familiaris
100526114 Sus scrofa
100138286 Bos taurus
307585 Rattus norvegicus
Selected quality suppliers for Cdk5 and Abl Enzyme Substrate 1 Proteins (CABLES1)
Did you look for something else?