anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) Antibodies

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Additionally we are shipping CCAR2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCAR2 57805 Q8N163
CCAR2    
CCAR2    
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Top anti-CCAR2 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using KIAA1967 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated WB Western blot analysis of KIAA1967 expression in A549 (A), HeLa (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB <b>Western blot</b> analysis of KIAA1967 / DBC-1 in A549 whole cell lysate using KIAA1967 antibody . 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using CCAR2 antibody. Immunohistochemistry of paraffin-embedded human kidney using CCAR2 antibody at dilution of 1:100 (x400 lens). 100 μL Log in to see 16 Days
$334.02
Details
Human Mouse Un-conjugated ICC, IP, WB   100 μL Log in to see 12 to 14 Days
$200.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to KIAA1967 on HeLa cell (antibody concentration 10 µg/mL). KIAA1967 monoclonal antibody (M04), clone 4E6 Western Blot analysis of KIAA1967 expression in A-549. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Cow Mouse Un-conjugated ICC, IF, WB   100 μL Log in to see 7 to 9 Days
$581.17
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 16 Days
$181.73
Details
Cow Goat Un-conjugated ELISA, WB ABIN2561628 (0.5µg/ml) staining of HEK293 (A) and MCF7 (B) nuclear lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN2561628 (2µg/ml) staining of NIH3T3 nuclear lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μL Log in to see 16 Days
$444.57
Details

CCAR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human
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Mouse (Murine)
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Rat (Rattus)
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More Antibodies against CCAR2 Interaction Partners

Human Cell Cycle and Apoptosis Regulator 2 (CCAR2) interaction partners

  1. conclude, these findings demonstrated that DBC1 was essential in tumorigenesis and proliferation. Moreover, it was identified as a potential therapeutic target for HCC (show FAM126A Antibodies).

  2. Long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 (show TP53 Antibodies) acetylation.

  3. Data suggest that DBC1 has a dual function in regulating beta-catenin (show CTNNB1 Antibodies)-PROX1 (show PROX1 Antibodies) signaling axis: as a coactivator for both beta-catenin (show CTNNB1 Antibodies) and PROX1 (show PROX1 Antibodies).

  4. important role for CCAR2 in maintaining cell cycle progression and promoting squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) tumorigenesis.

  5. Data show that the interaction between cell cycle and apoptosis regulator 2 (CCAR2) and heat shock protein 60 (Hsp60 (show HSPD1 Antibodies)) increases in the presence of rotenone.

  6. Results found transcriptional levels of DBC1,a negative regulator of HDAC3 (show HDAC3 Antibodies) significantly reduced in type 2 diabetes mellitus patients.

  7. DBC1 protein could be a prognostic marker of shorter recurrence-free survival in hepatocellular carcinoma patients after hepatectomy and human hepatocarcinogenesis was a multistep process accompanied by a stepwise increase in high DBC1 expression from low-grade dysplastic nodules, through high-grade dysplastic nodules, to hepatocellular carcinoma.

  8. Results suggest that DBC1 is integral to the maintenance of the circadian molecular clock.

  9. loss of DBC1 expression plays a role in tumorigenesis and tumor progression in gallbladder carcinoma.

  10. Proteosome-mediated degradation and poly-ubiquitination of AR were increased with the knock-down of DBC1.

CCAR2 Antigen Profile

Protein Summary

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.

Gene names and symbols associated with CCAR2

  • cell cycle and apoptosis regulator 2 (CCAR2) antibody
  • DBC-1 antibody
  • DBC1 antibody
  • KIAA1967 antibody
  • NET35 antibody
  • p30 DBC antibody
  • p30DBC antibody

Protein level used designations for CCAR2

DBIRD complex subunit KIAA1967 , deleted in breast cancer 1 , p30 DBC protein

GENE ID SPECIES
57805 Homo sapiens
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