Cell Cycle and Apoptosis Regulator 2 Proteins (CCAR2)

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Additionally we are shipping CCAR2 Antibodies (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCAR2 57805 Q8N163
CCAR2    
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Top CCAR2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details

CCAR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Cell Cycle and Apoptosis Regulator 2 (CCAR2) Interaction Partners

Human Cell Cycle and Apoptosis Regulator 2 (CCAR2) interaction partners

  1. important role for CCAR2 in maintaining cell cycle progression and promoting squamous cell carcinoma (SCC (show CYP11A1 Proteins)) tumorigenesis.

  2. Data show that the interaction between cell cycle and apoptosis regulator 2 (CCAR2) and heat shock protein 60 (Hsp60 (show HSPD1 Proteins)) increases in the presence of rotenone.

  3. Results found transcriptional levels of DBC1 (show DBC1 Proteins),a negative regulator of HDAC3 (show HDAC3 Proteins) significantly reduced in type 2 diabetes mellitus patients.

  4. DBC1 (show DBC1 Proteins) protein could be a prognostic marker of shorter recurrence-free survival in hepatocellular carcinoma patients after hepatectomy and human hepatocarcinogenesis was a multistep process accompanied by a stepwise increase in high DBC1 (show DBC1 Proteins) expression from low-grade dysplastic nodules, through high-grade dysplastic nodules, to hepatocellular carcinoma.

  5. Results suggest that DBC1 (show DBC1 Proteins) is integral to the maintenance of the circadian molecular clock.

  6. loss of DBC1 (show DBC1 Proteins) expression plays a role in tumorigenesis and tumor progression in gallbladder carcinoma.

  7. Proteosome-mediated degradation and poly-ubiquitination of AR were increased with the knock-down of DBC1 (show DBC1 Proteins).

  8. The results suggest that the PP4 (show ANXA5 Proteins)-mediated dephosphorylation of DBC1 (show DBC1 Proteins) is necessary for efficient damage responses in cells.

  9. These results indicate that the expression of DBC1 and BRCA1 are closely related with in the progression of ovarian carcinomas

  10. the results indicated that DBC1 (show DBC1 Proteins) promotes anoikis resistance in gastric cancer cells by regulating NF-kappaB (show NFKB1 Proteins) activity and may thus be a new therapeutic target for preventing potential metastasis

CCAR2 Protein Profile

Protein Summary

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.

Gene names and symbols associated with CCAR2

  • cell cycle and apoptosis regulator 2 (CCAR2)
  • DBC-1 protein
  • DBC1 protein
  • KIAA1967 protein
  • NET35 protein
  • p30 DBC protein
  • p30DBC protein

Protein level used designations for CCAR2

DBIRD complex subunit KIAA1967 , deleted in breast cancer 1 , p30 DBC protein

GENE ID SPECIES
57805 Homo sapiens
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