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Activates apoptosis.. Additionally we are shipping CIDEB Antibodies (105) and CIDEB Proteins (6) and many more products for this protein.
ICAD (show DFFA ELISA Kits) cDNA was 844-bp in length, containing a 522-bp open reading frame which encoded a protein of 174 amino acids.
this study shows that C5a signaling induces apoptosis in brain vascular endothelial cells in experimental lupus through activation of CIDEB
CIDEB downregulation may contribute to HCV-induced hepatic steatosis
CIDEB can act as an anti-HCV host factor and contribute to altered triglyceride homeostasis.
Authors found CIDEB to be an essential cofactor for hepatitis C virus entry into hepatocytes.
this work highlights CIDEB's role in lipid droplet (LD) fusion, and presents a new model system to study the PGC-1alpha (show PPARGC1A ELISA Kits)/CIDEB pathway's role in LD dynamics and the VLDL pathway.
CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma.
PGC-1alpha (show PPARGC1A ELISA Kits) plays an important role in partitioning cytoplasmic TG toward the VLDL secretory compartments and promoting VLDL secretion via transcriptional induction of CideB.
A novel mechanism for the cell-specific transcription of the human CIDE-B gene, which involves epigenetic and genetic control at separate respective promoters is reported.
Data (including data from studies in knockout mice) suggest Cideb promotes lipid storage as droplets in hepatocytes under normal diet conditions; Cidea (show CIDEA ELISA Kits)/Cidec (show CIDEC ELISA Kits) promote fusion of lipid droplets leading to liver steatosis in fasting (16h) and obese mice.
Cideb and perilipin 2 (show PLIN2 ELISA Kits) play opposing roles in controlling VLDL lipidation and hepatic lipid homeostasis
SREBP-1c (show SREBF1 ELISA Kits) mediates the effect of insulin (show INS ELISA Kits) on the expression of Cidea (show CIDEA ELISA Kits) in mouse hepatocytes.
Data suggest that Cideb is a novel regulator in controlling cholesterol homeostasis in the liver.
Cideb is a novel important regulator in lipid metabolism in the liver and may thus represent a new therapeutic target for the treatment of obesity, diabetes, and liver steatosis
Cideb protein promotes the formation of triacylglycerol-enriched VLDL particles and provides a molecular insight into VLDL lipidation and maturation in hepatocytes.
We therefore speculate that CIDEb may play a contrary role to the other CIDEs. The basic molecular information we provide here will be useful for further investigations of the physiological function of the gene, which will be helpful in better understanding the role of the CIDE family in lipid metabolism in pig models.
cell death-inducing DFFA-like effector b
, cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
, cell death activator CIDE-B
, cell death activator cide-b
, Cell death activator CIDE-B (Cell death-inducing DFFA-like effector B)
, DFFA-like B
, cell death-inducing DFFA-like effector B