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Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) ELISA Kits

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. Additionally we are shipping Cell Division Cycle 20 Homolog (S. Cerevisiae) Antibodies (82) and Cell Division Cycle 20 Homolog (S. Cerevisiae) Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CDC20 991 Q12834
CDC20 107995 Q9JJ66
CDC20 64515 Q62623
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More ELISA Kits for Cell Division Cycle 20 Homolog (S. Cerevisiae) Interaction Partners

Human Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Study describes a positive feedback loop centred on cyclin A2 (show CCNA2 ELISA Kits)-Cdk2 (show CDK2 ELISA Kits) inhibition of interphase APC (show APC ELISA Kits)/C-Cdc20 to allow further cyclin A2 (show CCNA2 ELISA Kits) accumulation and mitotic entry.

  2. Bub1 (show BUB1 ELISA Kits)-Plk1 (show PLK1 ELISA Kits)-mediated phosphorylation of Cdc20 constitutes an anaphase-promoting complex or cyclosome-inhibitory mechanism that is parallel, but not redundant, to mitotic checkpoint (show BUB3 ELISA Kits) complex formation.

  3. The presence of this segment correlates with SAC (show ADCY10 ELISA Kits) activity and efficient binding of CDC20 but not of MAD1 (show MXD1 ELISA Kits) to kinetochores.

  4. These results suggest CDC20 is a critical regulator of TIC (show ARNTL ELISA Kits) proliferation and survival, linking two key TIC (show ARNTL ELISA Kits) nodes-FOXM1 (show FOXM1 ELISA Kits) and p21CIP1/WAF1 (show CDKN1A ELISA Kits)-elucidating a potential point for therapeutic intervention.

  5. CDC20 is essential for the in vivo tumorigenicity of glioblastoma stem-like cells. CDC20 is prognostic of overall survival in Proneural subtype glioblastoma patients.

  6. BUB1B (show BUB1B ELISA Kits) expression was highly correlated to CDC20 and CCNB1 (show CCNB1 ELISA Kits) expression in multiple myeloma cells, leading to increased cell proliferation.

  7. spindle checkpoint release further increases APC (show APC ELISA Kits)/C(Cdc20) catalytic activity

  8. a Cdc20 binding site in BubR1 (show BUB1B ELISA Kits) facilitates both spindle assembly checkpoint signalling and silencing

  9. CDC20, MAD2 (show MAD2L1 ELISA Kits) and Aurora-B (show AURKB ELISA Kits) protein (show LEPREL2 ELISA Kits) expression are associated with chromosomal abnormalities and poor prognosis in patients with myelodysplastic syndromes.

  10. Results show that increased expression of CDC20 was demonstrated to be associated with the development and progression of hepatocellular carcinoma.

Xenopus laevis Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Cdc20 auto-ubiquitylation does not play a major role in terminating Cdc20 activation.

  2. Dephosphorylation of Cdc20 is required for its loading and activation of the APC/C ubiquitin ligase.

  3. A role for the fizzy/cdc20 family of proteins in activation of the APC (show APC ELISA Kits)/C distinct from substrate recruitment is reported.

Mouse (Murine) Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Cdc20 hypomorphism causes chromatin bridging and chromosome misalignment, revealing a requirement for Cdc20 in efficient sister chromosome separation and chromosome-microtubule attachment.

  2. The physiologically effective threshold level of Cdc20 is high for female meiosis I.

  3. Results indicate that Cdc20 also contributes to post-anaphase activation of the APC (show APC ELISA Kits)/C.

  4. The seven tandem WD motifs of Cdc20 they are required for speriolin binding and for localization of Cdc20 to the centrosomes and nucleus, suggesting that speriolin might regulate or stabilize the folding of Cdc20 during meiosis in spermatogenic cells

  5. Data suggest that Mad2 (show MXI1 ELISA Kits) and BubR1 (show BUB1B ELISA Kits) must cooperate to inhibit Cdc20 activity.

  6. Cdc20 is degraded through two independent degradation signals (degrons), the KEN (show PCNT ELISA Kits) box and a newly described CRY (show CRY2 ELISA Kits) box.

  7. Cdc20 and securin (show PTTG1 ELISA Kits) double mutant embryos could not maintain the metaphase arrest, suggesting a role of securin (show PTTG1 ELISA Kits) in preventing mitotic exit

  8. Expression of the cdc20 gene is down-regulated by zif268 (show EGR1 ELISA Kits) in neuronal cells; altered expression of proteasome-regulatory genes following zif268 (show EGR1 ELISA Kits) induction may be a key component of long-lasting CNS plasticity.

  9. Cdc20 is required for the anaphase onset of the first meiosis but not the second meiosis in mouse oocytes

  10. findings suggest a novel function of HSF1 (show HSF1 ELISA Kits) frequently overexpressed in cancer cells, to inhibit APC (show APC ELISA Kits)/C activity by interacting with Cdc20, and to result in aneuploidy development and genomic instability

Pig (Porcine) Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. porcine FZR1 and CDC20 work on the maintenance of meiotic arrest at the first meiotic prophase and on the exit from M1

Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) Antigen Profile

Antigen Summary

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.

Gene names and symbols associated with CDC20

  • cell division cycle 20 (cdc20) antibody
  • cell division cycle 20 (CDC20) antibody
  • cell division cycle 20 (Cdc20) antibody
  • cell division cycle 20 homolog (S. cerevisiae) (CDC20) antibody
  • 2310042N09Rik antibody
  • bA276H19.3 antibody
  • C87100 antibody
  • CDC20A antibody
  • fizzy1 antibody
  • p55CDC antibody
  • X-FZY antibody

Protein level used designations for CDC20

cell division cycle 20 homolog , CDC20 cell division cycle 20 homolog , cell division cycle protein 20 homolog , fizzy1 , mmCdc20 , cell cycle protein p55CDC , p55CDC

GENE ID SPECIES
394542 Xenopus (Silurana) tropicalis
991 Homo sapiens
398044 Xenopus laevis
107995 Mus musculus
64515 Rattus norvegicus
424563 Gallus gallus
482534 Canis lupus familiaris
397379 Sus scrofa
515376 Bos taurus
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