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Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) ELISA Kits

The protein encoded by CDC27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. Additionally we are shipping Cell Division Cycle 27 Homolog (S. Cerevisiae) Antibodies (108) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CDC27 996 P30260
CDC27 217232 A2A6Q5
CDC27 360643 Q4V8A2
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More ELISA Kits for Cell Division Cycle 27 Homolog (S. Cerevisiae) Interaction Partners

Human Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) interaction partners

  1. miR (show MLXIP ELISA Kits)-27a could modulate proliferation and radiosensitivity of TNBC cells. CDC-27 is a direct target of miR (show MLXIP ELISA Kits)-27a and its downregulation conferred increased radioresistance of the cells.

  2. These findings suggested that polymorphisms in cdc27 may contribute to the susceptibility of BC though functional studies are needed to further elucidate the underling mechanisms of the associations

  3. The structures show how one APC16 (show ANAPC16 ELISA Kits) binds asymmetrically to the symmetric APC3 dimer and, together with biochemistry and prior data, explain how APC16 (show ANAPC16 ELISA Kits) recruits APC7 (show ANAPC7 ELISA Kits) to APC3.

  4. Low cdc27 and high securin (show PTTG1 ELISA Kits) expression predict short survival for breast cancer patients.

  5. Down-regulation of CDC27 protein is associated with radiation resistance.

  6. Data indicate that additional density present in the anaphase-promoting complex (APC (show APC ELISA Kits)/C) structure, proximal to Apc3/Cdc27 of the (tetratricopeptide repeat) lobe, is assigned to the TPR subunit Apc7 (show ANAPC7 ELISA Kits), a subunit specific to vertebrate APC (show APC ELISA Kits)/C.

  7. the biochemical, structural, and cellular determinants of the novel interaction between MCPH1 (show MCPH1 ELISA Kits) and Cdc27 and suggest that this interaction may occur within the larger context of MCPH1 (show MCPH1 ELISA Kits)-APC (show APC ELISA Kits)/C.

  8. phosphorylation of Cdc27 by CKII (show CSNK2A1 ELISA Kits) is involved in TGF-beta (show TGFB1 ELISA Kits)-induced activation of APC (show APC ELISA Kits).

  9. Cdc20 (show CDC20 ELISA Kits) requires APC3 and APC8 (show CDC23 ELISA Kits) to bind and activate the APC (show APC ELISA Kits)/C when the spindle assembly checkpoint is satisfied, but only APC8 (show CDC23 ELISA Kits) when active, and APC10 (show ANAPC10 ELISA Kits) is crucial for the destruction of cyclin B1 (show CCNB1 ELISA Kits) and securin (show PTTG1 ELISA Kits), but not cyclin A (show CCNA2 ELISA Kits)

  10. the spindle checkpoint may regulate CDC27/APC (show APC ELISA Kits) activity at mitosis

Mouse (Murine) Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) interaction partners

  1. Cdc27 directs cyclin D1 (show CCND1 ELISA Kits) to alternative degradation by anaphase promoting complex/cyclosome.

Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) Antigen Profile

Antigen Summary

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CDC27

  • cell division cycle 27 homolog (S. cerevisiae) (CDC27) antibody
  • cell division cycle 27 (cdc27) antibody
  • cell division cycle 27 (CDC27) antibody
  • cell division cycle 27 (Cdc27) antibody
  • AI452358 antibody
  • ANAPC3 antibody
  • APC3 antibody
  • BC023187 antibody
  • CDC27 antibody
  • CDC27Hs antibody
  • D0S1430E antibody
  • D17S978E antibody
  • HNUC antibody
  • NUC2 antibody
  • NV10210 antibody

Protein level used designations for CDC27

cell division cycle 27 homolog (S. cerevisiae) , cell division cycle 27 homolog , cell division cycle protein 27 homolog , CDC27 homolog , H-NUC , anaphase promoting complex subunit 3 , anaphase-promoting complex subunit 3 , anaphase-promoting complex, protein 3 , nuc2 homolog

GENE ID SPECIES
717321 Macaca mulatta
779925 Xenopus (Silurana) tropicalis
100025278 Monodelphis domestica
100054552 Equus caballus
100123129 Nasonia vitripennis
100444022 Pongo abelii
100594961 Nomascus leucogenys
996 Homo sapiens
443994 Xenopus laevis
217232 Mus musculus
360643 Rattus norvegicus
419960 Gallus gallus
490924 Canis lupus familiaris
540660 Bos taurus
454815 Pan troglodytes
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