anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) Antibodies

The protein encoded by CDC37 is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. Additionally we are shipping CDC37 Proteins (19) and CDC37 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDC37 11140 Q16543
CDC37 12539 Q61081
CDC37 114562 Q63692
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Top anti-CDC37 Antibodies at antibodies-online.com

Showing 10 out of 150 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3/HT-29/RAW264.7 cells, using p50 CDC37 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Observed bind size: 44KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Dog Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of CDC37 on human endothelial lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of CDC37. WI38 50 μg Log in to see 6 to 8 Days
$154.07
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from MCF-7/COS7 cells, using CDC37 (Ab-13) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using CDC37 (Ab-13) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using CDC37 (Phospho-Ser13) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human placenta, using CDC37 (Phospho-Ser13) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Anti- Cdc37 antibody, Western blotting All lanes: Anti Cdc37 at 0.5ug/ml Lane 1: JURKAT Whole Cell Lysate at 40ug Lane 2: 293T Whole Cell Lysate at 40ug Predicted bind size: 44KD Observed bind size: 44KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: CDC37 Antibody [NBP1-80960] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: CDC37 Antibody [NBP1-80960] - Staining of human cell line A-431 shows positivity in cytoplasm. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti CDC37 Polyclonal Antibody, Unconjugated (ABIN706481) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti CDC37 Polyclonal Antibody, Unconjugated (ABIN706481) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Western Blot: CDC37 Antibody [ABIN4082870] - Western blot (WB) analyzes of CDC37 (F259) antibody in extracts from NIH-3T3 cells.. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 16 Days
$175.80
Details

CDC37 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CDC37 Antibodies

  1. Dog (Canine) Monoclonal CDC37 Primary Antibody for IF, IP - ABIN968047 : Grammatikakis, Lin, Grammatikakis, Tsichlis, Cochran: p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function. in Molecular and cellular biology 1999 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CDC37 Primary Antibody for ICC, IF - ABIN4296941 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

  3. Yeast (Saccharomyces cerevisiae) Polyclonal CDC37 Primary Antibody for IF, IP - ABIN2451938 : Reed: The selection of S. cerevisiae mutants defective in the start event of cell division. in Genetics 1981 (PubMed)
    Show all 3 Pubmed References

More Antibodies against CDC37 Interaction Partners

Fruit Fly (Drosophila melanogaster) Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

Human Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

  1. The results suggest a re-evaluation of the role of Cdc37 in the kinase lifecycle, and suggest that such interactions potentially allow kinases to more rapidly respond to key signals while simultaneously protecting unstable kinases from degradation and suppressing unwanted basal activity.

  2. Niclosamide ethanolamine disrupted the interaction between cell division cycle 37 and heat shock protein 90 (show HSP90 Antibodies) in hepatocellular carcinoma, reducing tumor growth.

  3. Cdc37 performs a quality control of protein kinases, including b-raf (show SNRPE Antibodies), where induced conformational instability acts as a "flag" for Hsp90 (show HSP90 Antibodies) dependence and stable cochaperone association.

  4. Ulk1 (show ULK1 Antibodies) promoted the degradation of Hsp90 (show HSP90 Antibodies)-Cdc37 client kinases, resulting in increased cellular sensitivity to Hsp90 (show HSP90 Antibodies) inhibitors. Thus, our study provides evidence for an anti-proliferative role of Ulk1 (show ULK1 Antibodies) in response to Hsp90 (show HSP90 Antibodies) inhibition in cancer cells

  5. The authors find that the interaction between sB-Raf (show RAF1 Antibodies) and the Hsp90 chaperone (show HSP90 Antibodies) system is based on contacts with the M domain of Hsp90 (show HSP90 Antibodies), which contributes in forming the ternary complex with Cdc37 as long as the kinase is not stabilized by nucleotide.

  6. Apart from these distinct Cdc37/Hsp90 interfaces, binding of the B-Raf protein kinase to the cochaperone is conserved between mammals and nematodes.

  7. Suppressing expression of the cochaperone CDC37 in hepatocellular carcinoma cells inhibits cell cycle progression and cell growth.

  8. RIP3 (show RIPK3 Antibodies) activation following the induction of necroptosis requires the activity of an HSP90 (show HSP90 Antibodies) and CDC37 cochaperone complex.

  9. Correlation between PDZK1 (show PDZK1 Antibodies), Cdc37, Akt (show AKT1 Antibodies) and breast cancer malignancy: the role of PDZK1 (show PDZK1 Antibodies) in cell growth through Akt (show AKT1 Antibodies) stabilization by increasing and interacting with Cdc37

  10. The N-terminal tail serves as an intramolecular chaperone ensuring that CDC37 assumes one of two interconvertible states in a manner impacting the interaction of the client binding N-domain and the MC-domains, involved in dimerization and HSP90 (show HSP90 Antibodies) binding.

Mouse (Murine) Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

  1. Niclosamide ethanolamine disrupted the interaction between cell division cycle 37 and heat shock protein 90 (show HSP90 Antibodies) in hepatocellular carcinoma, reducing tumor growth.

  2. A series of tyrosine phosphorylation events, involving both p50(Cdc37) and Hsp90 (show HSP90 Antibodies), are minimally sufficient to provide directionality to the chaperone cycle.

  3. Hsp90 (show HSP90 Antibodies)-Cdc37 complex acta (show ACTC1 Antibodies) as an endogenous regulator of noncanonical p38alpha (show MAPK14 Antibodies) activity.

  4. CDC37 binds to Akt (show AKT1 Antibodies) and HSP90 (show HSP90 Antibodies) in the signal transduction pathway in human tumor cells

  5. The interaction between mouse Pem and Cdc37 homolog was then confirmed by glutathione S-transferase (show GSTa2 Antibodies) pull-down assay, and the possible interaction model was suggested.

  6. JAK1 (show JAK1 Antibodies)/2 are client proteins of Hsp90 alpha (show HSP90AA1 Antibodies) and beta; Hsp90 (show HSP90 Antibodies) and CDC37 play a critical role in types I and II interferon (show IFNA Antibodies) pathways

  7. This growth inhibition is partially rescued by expression of ectopic Gli1 (show GLI1 Antibodies), suggesting that Fu may contribute to enhance Hh signaling activity in cancer cells.

Cow (Bovine) Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

  1. Cdc37 has a direct regulatory interaction with endothelial nitric oxide synthase (eNOS (show NOS3 Antibodies)) and may play an important role in mediating the eNOS (show NOS3 Antibodies) protein complex formation.

CDC37 Antigen Profile

Protein Summary

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Gene names and symbols associated with CDC37

  • CG12019 gene product from transcript CG12019-RA (Cdc37) antibody
  • cell division cycle 37 homolog (Cdc37) antibody
  • Hsp90 co-chaperone Cdc37 (cdc37) antibody
  • Hsp90 co-chaperone Cdc37 (AFUA_4G10010) antibody
  • Cdc37p (CDC37) antibody
  • cell division cycle 37 (CDC37) antibody
  • cell division cycle 37 (Cdc37) antibody
  • Afu4g10010 antibody
  • cdc37 antibody
  • CG12019 antibody
  • CPDR-1 antibody
  • CPDR-2 antibody
  • Dmel\\CG12019 antibody
  • DROCPDR antibody
  • E(sev)3B antibody
  • p50 antibody
  • p50Cdc37 antibody

Protein level used designations for CDC37

CG12019-PA , Cdc37-PA , cdc37 protein , hsp90 co-chaperone Cdc37 , Hsp90 co-chaperone Cdc37 , hypothetical protein , CDC37 (cell division cycle 37, S. cerevisiae, homolog) , CDC37 cell division cycle 37 homolog , cell division cycle 37 homolog , hsp90 chaperone protein kinase-targeting subunit , CDC37 (cell division cycle 37 S. cerevisiae homolog) , p50Cdc37 , CDC37 cell division cycle 37 protein , CDC37 homolog , cell division cycle 37 protein , cell division cycle control protein 37

GENE ID SPECIES
38232 Drosophila melanogaster
724675 Apis mellifera
2541293 Schizosaccharomyces pombe 972h-
3509722 Aspergillus fumigatus Af293
3639210 Candida albicans SC5314
11140 Homo sapiens
12539 Mus musculus
114562 Rattus norvegicus
484955 Canis lupus familiaris
100141402 Sus scrofa
520883 Bos taurus
395430 Gallus gallus
Selected quality suppliers for anti-CDC37 (CDC37) Antibodies
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