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anti-Cell Division Cycle 42 (CDC42) Antibodies

The protein encoded by CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDC42 12540 P60766
CDC42 100359703  
CDC42 998 P60953
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Top anti-CDC42 Antibodies at

Showing 3 out of 3 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 9 to 11 Days
Human Rabbit Un-conjugated 50 μL Log in to see 9 to 14 Days
Human Rabbit Un-conjugated 100 μg Log in to see 29 to 34 Days

CDC42 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)

Rat (Rattus)


More Antibodies against CDC42 Interaction Partners

Mouse (Murine) Cell Division Cycle 42 (CDC42) interaction partners

  1. presentation of a form of biochemical computation in dendrites involving the controlled complementation of three molecules--Rac1, RhoA (show RHOA Antibodies) and Cdc42--that simultaneously ensures signal specificity and primes the system for BDNF (show BDNF Antibodies)-dependent homo- and heterosynaptic plasticity

  2. Cdc42 is involved not in osteogenesis but in chondrogenesis in which the BMP2 (show BMP2 Antibodies)/Cdc42/Pak/p38 (show CRK Antibodies)/Smad (show SMAD1 Antibodies) signaling module promotes mesenchymal condensation and the TGF-beta (show TGFB1 Antibodies)/Cdc42/Pak/Akt (show AKT1 Antibodies)/Sox9 (show SOX9 Antibodies) signaling module facilitates chondrogenic differentiation.

  3. These data show that membrane protrusions originate from surface ectodermal cells and that Rac1 is necessary for the formation of membrane ruffles which typify late neural fold closure stages, whereas Cdc42 is required for the predominance of filopodia in early neurulation.

  4. findings demonstrate that Cdc42 plays essential roles in mammary gland function post pregnancy, where it helps to establish proper epithelial cell polarity and tissue homeostasis during lactation.

  5. This work demonstrated miR (show MLXIP Antibodies)-137 and CDC42 are critical regulators in cardiomyocyte apoptosis.

  6. the principal role of Cdc42 in ureteric bud and metanephric mesenchyme development is to regulate epithelial cell polarity and the actin cytoskeleton.

  7. indicate that restricted expression of Wnt5a (show WNT5A Antibodies) in the caudal (show CAD Antibodies) SpM (show NPC1 Antibodies) is essential for normal OFT morphogenesis, and uncover a novel function of spatially regulated cell cohesion by Wnt5a (show WNT5A Antibodies) in driving the deployment of SHF (show SHF Antibodies) cells from the SpM (show NPC1 Antibodies) into the OFT

  8. role of P-cadherin through beta-PIX (show ARHGEF7 Antibodies)-mediated Cdc42 activation in the regulation of cell polarity

  9. Thus, Cdc42 and Rac1 have nonredundant roles in controlling ALK (show ALK Antibodies)-rearranged lymphoma survival and morphology but are redundant for lymphoma dissemination

  10. Knockdown of Fat1 (show FAT1 Antibodies) in renal tubular cells decreases active RAC1 and CDC42.

Human Cell Division Cycle 42 (CDC42) interaction partners

  1. Our results demonstrate a novel role of Bif-1 (show ZBTB24 Antibodies) in hepatocellular carcinoma (HCC (show FAM126A Antibodies)), in which Bif-1 (show ZBTB24 Antibodies) promotes cell metastasis by regulating Cdc42 expression and activity.

  2. A polysaccharide from Pinellia ternata inhibits cell proliferation and metastasis in human cholangiocarcinoma cells by targeting of Cdc42 and 67kDa (show RPSA Antibodies) Laminin Receptor

  3. we found that CXCR4 (show CXCR4 Antibodies)-CXCL12 (show CXCL12 Antibodies)/AKT (show AKT1 Antibodies) axis regulates RhoA (show RHOA Antibodies), Rac-1, and Cdc42 to modulate cell invasion and tumor metastasis. Together, these results demonstrate a role for CXCR4 (show CXCR4 Antibodies) in ESCC metastasis and progression and suggest potential targets for therapeutic intervention.

  4. Low gene dosage of cdc42 is not associated with protein dysfunction in patients with colorectal cancer.

  5. We have reported here for the first time a reduced activity of both Rac1 and Cdc42 in human pheochromocytoma resection as well as tumor-associated expression changes of FARP1 (show FARP1 Antibodies), ARHGEF1 (show ARHGEF1 Antibodies), and ARHGAP36 (show ARHGAP36 Antibodies)

  6. PAK6 (show PAK6 Antibodies) localization to cell-cell adhesions is Cdc42-dependent

  7. Golgi-localized Cdc42 enables the cell to diversify the function of Cdc42, which in some cases represents new roles and in other cases acts to complement the established roles of Cdc42 at the plasma membrane.

  8. The present observation provides further evidence supporting the notion that a mutation in CDC42 causes a recognizable syndromic form of thrombocytopenia.

  9. the Cdc42/Nwasp (show WASL Antibodies)/stress fibers/YAP (show YAP1 Antibodies) signal pathway may potentially play an important role in regulating podocyte apoptosis. Maintaining necessary Cdc42 would be one potent way to prevent proteinuria kidney diseases.

  10. we identified Cdc42 as a potentially essential biomarker for trichohepatoenteric syndrome

CDC42 Antigen Profile

Protein Summary

The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.

Gene names and symbols associated with CDC42

  • cell division cycle 42 (cdc42) antibody
  • cell division cycle 42 (Cdc42) antibody
  • cell division cycle 42 (LOC100359703) antibody
  • cell division cycle 42 (CDC42) antibody
  • AI747189 antibody
  • AU018915 antibody
  • cdc42 antibody
  • CDC42Hs antibody
  • G25K antibody

Protein level used designations for CDC42

cell division cycle 42 , Rho family small GTP binding protein cdc42 , G25K GTP-binding protein , cell division control protein 42 homolog , cell division cycle 42 homolog , GTP binding protein, 25kDa , GTP-binding protein, 25kD , dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)) , dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)) , growth-regulating protein , small GTP binding protein CDC42

445701 Ciona intestinalis
100145828 Acyrthosiphon pisum
12540 Mus musculus
100359703 Rattus norvegicus
998 Homo sapiens
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