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CDC7 encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. Additionally we are shipping CDC7 Proteins (4) and many more products for this protein.
Showing 10 out of 66 products:
Human Polyclonal CDC7 Primary Antibody for WB - ABIN1882165
Sato, Arai, Masai: Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7. in The EMBO journal 1997
Show all 4 references for ABIN1882165
Human Polyclonal CDC7 Primary Antibody for ELISA, WB - ABIN1533477
Hess, Drong, Weiland, Slightom, Sclafani, Hollingsworth: A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines. in Gene 1998
Human Monoclonal CDC7 Primary Antibody for IHC (p), IP - ABIN180694
Sclafani: Cdc7p-Dbf4p becomes famous in the cell cycle. in Journal of cell science 2000
Human Monoclonal CDC7 Primary Antibody for ICC, IF - ABIN265783
Hubbi, Kshitiz, Gilkes, Rey, Wong, Luo, Kim, Dang, Levchenko, Semenza: A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication. in Science signaling 2013
Human Polyclonal CDC7 Primary Antibody for IHC (p) - ABIN4296982
Kitamura, Fukatsu, Kakusho, Cho, Taniyama, Yamazaki, Toh, Yanagi, Arai, Chang, Masai: Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognition. in The Journal of biological chemistry 2011
Our data show that Cdc7 is highly expressed in colorectal cancer
The presence of the index SNP rs1192415 (TGFBR3 (show TGFBR3 Antibodies)-CDC7) was associated with visual field progression in POAG (primary open-angle glaucoma) patients.
MiR (show MLXIP Antibodies)-630 promoted apoptosis by downregulation of CDC7.
The state of DUE-B phosphorylation is maintained by the equilibrium between Cdc7-dependent phosphorylation and PP2A (show PPP2R4 Antibodies)-dependent dephosphorylation.
The interaction between Claspin (show CLSPN Antibodies) and Cdc7 is not dependent on Cdc7 kinase activity, but Claspin (show CLSPN Antibodies) interaction with the DNA helicase subunit Mcm2 (show MCM2 Antibodies) is lost upon Cdc7 inhibition.
huCdc7 may play an important role in the development and progression of colorectal cancer.
The results suggest that CDC7 expression level can be specific prognostic factors for Diffuse large B-cell lymphoma patients
Cdc7 phosphorylates and interacts with Tob (show TDO2 Antibodies) to inhibit the Cul4-DDB1 (show DDB1 Antibodies)(Cdt2 (show DTL Antibodies))-dependent Tob (show TDO2 Antibodies) degradation.
cell death process induced by Cdc7 depletion
bipartite interaction between Cdc7 and Dbf4 (show DBF4 Antibodies)/ASK subunits facilitates ATP binding and substrate recognition by the Cdc7 kinase.
Cdc7 physically and functionally interacts with Nkx2.5 (show NKX2-5 Antibodies) to regulate Myocd (show MYOCD Antibodies) promoter activity
Cdc7 mediates SMC (show DYM Antibodies) differentiation through a mechanism distinct from cell proliferation.
MCM4 (show MCM4 Antibodies) phosphorylation by Cdc7 kinase facilitates its interaction with Cdc45 (show CDC45 Antibodies) on chromatin
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
cell division cycle 7-related protein kinase
, CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1
, CDC7-related kinase
, cell division cycle 7 homolog
, cell division cycle 7-like protein 1
, cell division cycle 7-like 1