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anti-Centrobin, Centrosomal BRCA2 Interacting Protein (CNTROB) Antibodies

CNTROB encodes a centrosomal protein that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CNTROB 116840 Q8N137
CNTROB 216846 Q8CB62
CNTROB 303240  
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Top anti-Centrobin, Centrosomal BRCA2 Interacting Protein Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB CNTROB Antibody (Center) western blot analysis in mouse Neuro-2a cell line lysates (35µg/lane).This demonstrates the CNTROB antibody detected the CNTROB protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using CNTROB Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB CNTROB Antibody (Center)  western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CNTROB antibody detected the CNTROB protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Anti-CNTROB antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1100865 dilution 10 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of CNTROB expression in transfected 293T cell line by CNTROB MaxPab polyclonal antibody.Lane 1: CNTROB transfected lysate(99.33 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

CNTROB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Centrobin, Centrosomal BRCA2 Interacting Protein Antibodies

  1. Human Polyclonal CNTROB Primary Antibody for EIA, WB - ABIN951474 : Lee, Jeong, Jeong, Rhee: Centrobin/NIP2 is a microtubule stabilizer whose activity is enhanced by PLK1 phosphorylation during mitosis. in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 references for ABIN951474

  2. Human Polyclonal CNTROB Primary Antibody for WB - ABIN530406 : Hori, Peddie, Collinson, Toda: Centriolar satellite- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly. in Molecular biology of the cell 2015 (PubMed)

More Antibodies against Centrobin, Centrosomal BRCA2 Interacting Protein Interaction Partners

Human Centrobin, Centrosomal BRCA2 Interacting Protein (CNTROB) interaction partners

  1. cytoplasmic centrobin has roles in noncentrosomal microtubule formation in specific cell types and during the cell cycle

  2. Centrobin plays a role in the stability and centriole elongation function of CPAP (show CENPJ Antibodies) and limits the centriole length.

  3. Centrobin-CPAP (show CENPJ Antibodies) interaction is critical for the recruitment of CPAP (show CENPJ Antibodies) to procentrioles to promote the elongation of daughter centrioles and for the persistence of CPAP (show CENPJ Antibodies) on preexisting mother centrioles.

  4. it is proposed that Centrobin might regulate microtubule nucleation and organization by controlling the amount of pericentriolar matrix

  5. NEK2 (show NEK2 Antibodies) phosphorylation antagonizes the microtubule stabilizing activity of centrobin.

  6. Our results indicate that genetic polymorphisms of centrobin and Nek2 are related to breast cancer susceptibility in Chinese Han women.

  7. Centrobin facilitates the elongation and stability of centrioles via its interaction with tubulins.

  8. Data propose that centrobin functions as a microtubule stabilizing factor and PLK1 (show PLK1 Antibodies) enhances centrobin activity for proper spindle formation during mitosis.

  9. a requirement of Centrobin in maintaining centrosome integrity, which in turn promotes anchoring of mitotic spindle to the centrosomes.

  10. Inhibition of p38 (show CRK Antibodies) activity or downregulation of p38 (show CRK Antibodies) expression could overcome the cell-cycle arrest caused by centrobin depletion.

Mouse (Murine) Centrobin, Centrosomal BRCA2 Interacting Protein (CNTROB) interaction partners

  1. cytoplasmic centrobin has roles in noncentrosomal microtubule formation in specific cell types and during the cell cycle

  2. Centrobin may be a possible substrate of Nek2 (show NEK2 Antibodies) responsible for the meiotic spindle assembly in the mouse oocytes.

  3. Data show that a residual amount of centrobin was detected at the centrosomes of the resting cells, suggesting its role for maintaining integrity of the centrosome, especially of the daughter centriole in the cells.

  4. The phenotypic similarities of the Nip2/centrobin- and Nek2 (show NEK2 Antibodies)-suppressed embryos suggest that Nip2/centrobin may be a substrate of Nek2 (show NEK2 Antibodies) that is required for mitotic spindle assembly in early mouse embryos.

Centrobin, Centrosomal BRCA2 Interacting Protein (CNTROB) Antigen Profile

Protein Summary

This gene encodes a centrosomal protein that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with CNTROB

  • centrobin, centrosomal BRCA2 interacting protein (CNTROB) antibody
  • centrobin, centrosomal BRCA2 interacting protein (cntrob) antibody
  • centrobin-like (LOC539106) antibody
  • centrobin, centrosomal BRCA2 interacting protein (Cntrob) antibody
  • 9830165K03Rik antibody
  • CNTROB antibody
  • Lip8 antibody
  • RGD1307488 antibody

Protein level used designations for CNTROB

centrobin, centrosomal BRCA2 interacting protein , LYST-interacting protein LIP8 , centrobin-like , LYST-interacting protein 8 , centrobin , centrosomal BRCA2-interacting protein

GENE ID SPECIES
468436 Pan troglodytes
489484 Canis lupus familiaris
716660 Macaca mulatta
100048929 Xenopus (Silurana) tropicalis
100345619 Oryctolagus cuniculus
100390727 Callithrix jacchus
100442611 Pongo abelii
100582426 Nomascus leucogenys
539106 Bos taurus
116840 Homo sapiens
216846 Mus musculus
303240 Rattus norvegicus
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