Centromere Protein B Proteins (CENPB)

CENPB product is a highly conserved protein that facilitates centromere formation. Additionally we are shipping Centromere Protein B Antibodies (41) and Centromere Protein B Kits (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CENPB 12616 P27790
Rat CENPB CENPB 362217  
CENPB 1059 P07199
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Top Centromere Protein B Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Sheep His tag   1 mg Log in to see 60 to 71 Days
$2,607.00
Details
HOST_Insect cells (Sf9) Human His tag   1 mg Log in to see 2 to 3 Days
$4,339.50
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

CENPB Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Centromere Protein B (CENPB) Interaction Partners

Mouse (Murine) Centromere Protein B (CENPB) interaction partners

  1. demonstrate a novel ADA3 (show TADA3 Proteins) interaction with CENP-B-centromere that may account for its previously known function in mitosis

  2. Cenpa (show CENPA Proteins), Cenpb, and Bub3 (show BUB3 Proteins), but not Cenpc, interacted with PARP-1 (show PARP1 Proteins)

  3. This study shows that ICP0 induces the proteasomal-dependent degradation of the centromeric protein CENP-B in infected as well as ICP0-expressing cells.

  4. Propose that CENP-B plays a dual role in centromere formation, ensuring de novo formation on DNA lacking a functional centromere but preventing the formation of excess centromeres on chromosomes.

Human Centromere Protein B (CENPB) interaction partners

  1. Findings indicate that expression of the scleroderma autoantigens IFI-16 (show IFI16 Proteins) and CENPs (show APITD1 Proteins), which are associated with severe vascular disease, is increased in vascular progenitors and mature endothelial cells. High level, lineage-enriched expression of autoantigens may explain the striking association between clinical phenotypes and the immune targeting of specific autoantigens.

  2. The results indicated that CENPB boxes are highly conserved in Down syndrome (DS) patients and may not be responsible for Chr21 nondisjunction events. However, alphasatDNA in Chr21 is variable and deoxynucleotide deletions, mutations and polymorphisms may act as potential molecular diagnostic markers of DS.

  3. CENP-B directly binds both CENP-A's amino-terminal tail and CENP-C, a key nucleator of kinetochore assembly

  4. The results revealed that CENP-B binding in the vicinity of the CENP-A (show CENPA Proteins) nucleosome substantially stabilizes the CENP-A (show CENPA Proteins) nucleosome on alphoid DNA in human cells.

  5. Centromere protein B (CENP-B) as a novel interacting partner of HBZ (show HBZ Proteins).

  6. INMAP as a model regulator of CENP-B

  7. N-terminal methylation is required for CENP-B's binding to the CENP-B box.

  8. Human Nap1 (show IL8 Proteins), an acidic histone chaperone, inhibited the non-specific binding of CENP-B to nucleosomes and apparently stimulated CENP-B binding to its cognate CENP-B box DNA.

  9. CENP-A (show CENPA Proteins) and/or B status is predictive of the extent of skin involvement over time in systemic sclerosis.

  10. Anti-CENP-B autoantibodies in breast cancer patients prolong disease-free and overall survival.

Centromere Protein B (CENPB) Protein Profile

Protein Summary

This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.

Gene names and symbols associated with Centromere Protein B Proteins (CENPB)

  • CENP-B protein (CENP-B)
  • centromere protein B (Cenpb)
  • centromere protein B-like (LOC100356278)
  • centromere protein B, 80kDa (CENPB)
  • CENP-B protein
  • CENPB protein

Protein level used designations for Centromere Protein B Proteins (CENPB)

CENP-B protein , centromere protein B , Major centromere autoantigen B , CENP-B , centromere autoantigen B , major centromere autoantigen B , centromere autoantigen protein B

GENE ID SPECIES
443351 Ovis aries
12616 Mus musculus
362217 Rattus norvegicus
100689274 Cricetulus griseus
100356278 Oryctolagus cuniculus
1059 Homo sapiens
485791 Canis lupus familiaris
788381 Bos taurus
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