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Centrosomal Protein 250kDa (CEP250) ELISA Kits

CEP250 encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. Additionally we are shipping CEP250 Antibodies (8) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat CEP250 CEP250 311573  
Anti-Mouse CEP250 CEP250 16328 Q60952
Anti-Human CEP250 CEP250 11190 Q9BV73
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More ELISA Kits for CEP250 Interaction Partners

Cow (Bovine) Centrosomal Protein 250kDa (CEP250) interaction partners

  1. Caprine-like Generalized Hypoplasia Syndrome is caused by a truncating mutation in the CEP250 gene. Loss of C-Nap1-mediated centriole cohesion leads to an altered cell migration phenotype.

Mouse (Murine) Centrosomal Protein 250kDa (CEP250) interaction partners

  1. CEP2 attenuates myoblast differentiation but does not affect proliferation.

Human Centrosomal Protein 250kDa (CEP250) interaction partners

  1. ASPP1 (show PPP1R13B ELISA Kits)/2 interacted with centrosome linker protein (show LAT ELISA Kits) C (show PROC ELISA Kits)-Nap1. Co-depletion of ASPP1 (show PPP1R13B ELISA Kits) and ASPP2 (show TP53BP2 ELISA Kits) inhibited re-association of C-Nap1 with centrosome at the end of mitosis.

  2. A homozygous nonsense CEP250 mutation, in combination with a heterozygous C2orf71 nonsense mutation, causes an atypical form of Usher syndrome, characterised by early-onset sensorineural hearing loss and a relatively mild retinitis pigmentosa.

  3. Centlein complexes with C-Nap1 and Cep68 at the proximal ends of centrioles during interphase.

  4. C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis.

  5. Data show that the dissociation of C-Nap1 from mitotic centrosomes is regulated by localized phosphorylation rather than generalized proteolysis.

  6. CEP135 (show CEP135 ELISA Kits) acts as a platform protein for C-NAP1 at the centriole.

CEP250 Antigen Profile

Antigen Summary

This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome.

Gene names and symbols associated with CEP250

  • centrosomal protein 250kDa (CEP250) antibody
  • centrosomal protein 250kDa (cep250) antibody
  • centrosomal protein 250 (Cep250) antibody
  • AW490617 antibody
  • B230210E21Rik antibody
  • C-NAP1 antibody
  • CEP2 antibody
  • CEP250 antibody
  • CNAP1 antibody
  • Inmp antibody
  • RGD1562262 antibody

Protein level used designations for CEP250

centrosomal protein 250kDa , centrosome-associated protein CEP250 , centrosomal protein 250kDa, isoform 1 , centrosomal protein 2 , centrosome-associated protein CEP250-like , 250 kDa centrosomal protein , C-Nap1 , centrosomal Nek2-associated protein 1 , intranuclear matrix protein , centrosomal protein, 250-KD , centrosome associated protein

GENE ID SPECIES
419138 Gallus gallus
485851 Canis lupus familiaris
507479 Bos taurus
705173 Macaca mulatta
100032480 Monodelphis domestica
100069526 Equus caballus
100137602 Papio anubis
100151840 Sus scrofa
100355443 Oryctolagus cuniculus
100484176 Ailuropoda melanoleuca
100558279 Anolis carolinensis
100605479 Nomascus leucogenys
311573 Rattus norvegicus
16328 Mus musculus
11190 Homo sapiens
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