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Ceramide Kinase (CERK) ELISA Kits

CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Additionally we are shipping CERK Antibodies (64) and CERK Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CERK 64781 Q8TCT0
CERK 223753 Q8K4Q7
Anti-Rat CERK CERK 300129  
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Showing 2 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 1.44 ng/mL 3.13-200 ng/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 11 to 13 Days

More ELISA Kits for CERK Interaction Partners

Human Ceramide Kinase (CERK) interaction partners

  1. our findings identify a functional role for Cerk in breast cancer recurrence and suggest the clinical utility of agents targeted against this prosurvival pathway.

  2. Data suggest that inhibition of ceramide kinase (CerK) [by specific gene silencing or pharmacological inhibition] drastically reduced cell proliferation in a neuroblastoma (show ARHGEF16 ELISA Kits) cell line.

  3. TNF-alpha (show TNF ELISA Kits) exposure of human SH-SY5Y neuroblastoma (show ARHGEF16 ELISA Kits) caused a profound increase in CERK activity.

  4. Expression of hCERK enhanced ceramide-1-phosphate formation and release of arachidonic acid in Ca(2 (show CA2 ELISA Kits)+) ionophore-stimulated cells.

  5. We have identified a differential role for ceramide kinase in mast-cell activation

  6. ceramide kinase and its product, C-1-P, have roles in arachidonic acid release and production of eicosanoids

  7. CERK translocates during activation from the cytosol to a lipid raft fraction

  8. Pleckstrin (show PLEK ELISA Kits) homology domain of CERK is not only indispensable for its activity but also act as a regulator of CERK activity.

  9. sphingoid chain was also required for substrate recognition by CERK

  10. Recombinant CERK was analyzed with regard to dependence on divalent cations, to substrate delivery, specificity, and stereoselectivity. CERK associated with the plasma membrane in CHO (show COL11A1 ELISA Kits) cells, which is mediated by the N-terminal putative pleckstrin (show PLEK ELISA Kits) domain.

Mouse (Murine) Ceramide Kinase (CERK) interaction partners

  1. there are significant differences in eicosanoid levels in ex vivo CERK(-/-) cells compared with wild-type counterparts, but the effect of the genetic ablation of CERK on eicosanoid synthesis and the serum levels of C1P was not apparent in vivo

  2. role of ceramide kinase in obesity and insulin (show INS ELISA Kits) resistance

  3. Results indicate that C1P produced by CERK has a negative effect on the processing/secretion of TNFalpha (show TNF ELISA Kits) via modulation of TACE (show ADAM17 ELISA Kits) activity.

  4. role of CerK on the activation of mast cells

  5. The mechanism of ceramide-mediated inhibition is likely to involve conversion of ceramide to ceramide 1-phosphate by CERK.

  6. LPS (show TLR4 ELISA Kits) inhibits the transcriptional activity of the Cerk proximal promoter;transcriptional repression of Cerk by LPS (show TLR4 ELISA Kits) is not a primary consequence of LPS (show TLR4 ELISA Kits)-induced cell cycle blockade.

  7. Findings suggest that CerK is not necessary for survival at an individual level, but might be involved in higher brain function related to emotion.

  8. CerK is essential to ceramide 1-phosphate formation via phosphorylation of Cer (show CBLN1 ELISA Kits)

  9. Ceramide kinase is a key regulator of ceramide 1-phosphate, dihydroceramide and ceramide levels, with important implications for neutrophil homeostasis and innate immunity regulation.

CERK Antigen Profile

Antigen Summary

CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006

Gene names and symbols associated with Ceramide Kinase (CERK) ELISA Kits

  • ceramide kinase (CERK) antibody
  • ceramide kinase (cerk) antibody
  • zgc:158263 (zgc:158263) antibody
  • ceramide kinase (CpipJ_CPIJ003342) antibody
  • ceramide kinase (LOAG_11245) antibody
  • Ceramide kinase (Cerk) antibody
  • ceramide kinase (AaeL_AAEL015603) antibody
  • Ceramide kinase (Bm1_50005) antibody
  • ceramide kinase (Cerk) antibody
  • AI848610 antibody
  • CERK antibody
  • CG16708 antibody
  • D330016D08Rik antibody
  • dA59H18.2 antibody
  • dA59H18.3 antibody
  • dcerk antibody
  • Dmel\\CG16708 antibody
  • hCERK antibody
  • LK4 antibody
  • MGC81777 antibody
  • mKIAA1646 antibody
  • si:ch211-162i19.1 antibody

Protein level used designations for Ceramide Kinase (CERK) ELISA Kits

ceramide kinase , CG16708-PA , CG16708-PB , Cerk-PA , Cerk-PB , Ceramide kinase , acylsphingosine kinase , lipid kinase 4 , lipid kinase LK4 , mCERK

100053604 Equus caballus
474464 Canis lupus familiaris
458921 Pan troglodytes
425523 Gallus gallus
558496 Danio rerio
444466 Xenopus laevis
791197 Danio rerio
6034795 Culex quinquefasciatus
9948698 Loa loa
40640 Drosophila melanogaster
5579301 Aedes aegypti
6104885 Brugia malayi
64781 Homo sapiens
223753 Mus musculus
100336737 Bos taurus
300129 Rattus norvegicus
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