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Cereblon (CRBN) ELISA Kits

CRBN encodes a protein related to the Lon protease protein family. Additionally we are shipping Cereblon Antibodies (32) and Cereblon Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CRBN 297498 Q56AP7
CRBN 51185 Q96SW2
CRBN 58799 Q8C7D2
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Top Cereblon ELISA Kits at

Showing 5 out of 17 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 9.38 pg/mL 37.5-2400 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
Mouse 0.057 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days

More ELISA Kits for Cereblon Interaction Partners

Human Cereblon (CRBN) interaction partners

  1. 45.2 of multiple myeloma patients were CRBN(+). Among patients treated with thalidomide-based regimens, CRBN(+) patients showed a better treatment response than did CRBN-negative patients. There was no significant difference in survival outcomes between thalidomide- and bortezomib-based regimens in CRBN(+) patients.

  2. These results support the notion that the cereblon binding partner AGO2 (show EIF2C2 ELISA Kits) plays an important role in regulating MM cell growth and survival and AGO2 (show EIF2C2 ELISA Kits) could be considered as a novel drug target for overcoming IMiD resistance in MM cells.

  3. The anti-PEL effects of IMiDs involved cereblon-dependent suppression of IRF4 (show IRF4 ELISA Kits) and rapid degradation of IKZF1 (show IKZF1 ELISA Kits), but not IKZF3 (show IKZF3 ELISA Kits). Small hairpin RNA-mediated knockdown of MYC (show MYC ELISA Kits) enhanced the cytotoxicity of IMiDs

  4. GS is acetylated at lysines 11 and 14, yielding a degron that is necessary and sufficient for binding and ubiquitylation by CRL4(CRBN) and degradation by the proteasome.

  5. Structural dynamics of the cereblon ligand binding domain.

  6. Our data are consistent with the idea that the CUL4A (show CUL4A ELISA Kits)/B-DDB1 (show DDB1 ELISA Kits)-CRBN complex catalyses the polyubiquitination and thus controls the degradation of CLC-1 (show CLCN1 ELISA Kits) channels.

  7. Data suggest that cereblon (CRBN) expression in peripheral blood chronic lymphocytic leukemia (CLL) cells is independent of prognostic factors and may be considered a potential biomarker.

  8. High levels of full-length CRBN mRNA in lower risk 5q deletion patients are necessary for the efficacy of lenalidomide.

  9. A copy number gain of CRBN gene might be responsible for developmental delay/intellectual disability.

  10. Although abnormal CRBN function may be associated with intellectual disability disease onset, its cellular mechanism is still unclear. Here, we examine the role of CRBN in aggresome formation and cytoprotection.

Mouse (Murine) Cereblon (CRBN) interaction partners

  1. CRBN is involved in the activation of PERK (show EIF2AK3 ELISA Kits) and the Ire1 (show ERN1 ELISA Kits) pathway of the unfolded protein response.CRBN plays a role in cellular stress signaling, including the unfolded protein response, by controlling the activity of AMPK (show PRKAA1 ELISA Kits).

  2. results of this study suggest a plausible mechanism for CRBN involvement in higher brain function in humans, and they may help explain how a specific mutation in CRBN can affect the cognitive ability of patients

  3. Found significantly smaller infarct sizes and less fibrosis in the hearts of CRBN KO mice than in those of WT mice. Apoptosis was also significantly reduced in the KO mice compared with that in WT mice.

  4. findings suggest that crbn-/- mice exhibit selective HPC-dependent deficits in associative learning.

  5. CRBN directly interacts with the alpha1 subunit of AMP-activated protein kinase (AMPK (show PRKAA2 ELISA Kits) alpha1) and inhibits the activation of AMPK (show PRKAA1 ELISA Kits) activation.

  6. These results imply that Nrf2 (show NFE2L2 ELISA Kits) stimulates CRBN gene transcription under hypoxia-reoxygenation conditions in neuronal cells.

Cereblon (CRBN) Antigen Profile

Antigen Summary

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Cereblon (CRBN) ELISA Kits

  • cereblon (crbn) antibody
  • cereblon (CRBN) antibody
  • ATP-dependent protease La (LON) domain protein (AT2G25740) antibody
  • cereblon (Crbn) antibody
  • 2610203G15Rik antibody
  • 2900045O07Rik antibody
  • AF229032 antibody
  • AW108261 antibody
  • F3N11.21 antibody
  • MRT2 antibody
  • MRT2A antibody
  • piL antibody
  • zgc:92404 antibody

Protein level used designations for Cereblon (CRBN) ELISA Kits

protein cereblon , zcrbn , cereblon , protein cereblon-like , protein x 0001 , novel lethal , protein PiL , Protein cereblon

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493554 Xenopus (Silurana) tropicalis
100022278 Monodelphis domestica
100479474 Ailuropoda melanoleuca
817117 Arabidopsis thaliana
100584605 Nomascus leucogenys
297498 Rattus norvegicus
51185 Homo sapiens
58799 Mus musculus
511585 Bos taurus
416104 Gallus gallus
476551 Canis lupus familiaris
100174633 Pongo abelii
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