Cerebral Dopamine Neurotrophic Factor Proteins (CDNF)

Trophic factor for dopamine neurons. Additionally we are shipping CDNF Antibodies (83) and CDNF Kits (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CDNF 441549 Q49AH0
CDNF 227526 Q8CC36
CDNF 361276 P0C5I0
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Top CDNF Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days
$528.00
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HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 15 to 18 Days
$560.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$575.00
Details
HOST_Human Human His tag   10 μg Log in to see 15 to 16 Days
$212.50
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$704.00
Details

CDNF Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,
Mouse (Murine) , ,
,
Rat (Rattus) ,

More Proteins for Cerebral Dopamine Neurotrophic Factor (CDNF) Interaction Partners

Human Cerebral Dopamine Neurotrophic Factor (CDNF) interaction partners

  1. The results showed that AAV8-CDNF administration significantly improved the motor function and increased the tyrosine hydroxylase (TH (show TH Proteins)) levels in Parkinson's disease rats with mild lesions (2 weeks post lesion), but it had limited therapeutic effects in rats with severe lesions (5 weeks post lesion).

  2. Results suggest that CDNF treatment selectively enhances long-term memory consolidation

  3. showed that CDNF was able to protect dopaminergic neurons against injury caused by alpha-synuclein oligomers. This advises its use against physiological damages caused by alpha-synuclein oligomers

  4. Expression of CDNF in the substantia nigra has an anti-inflammatory effect on experimental Parkinson's disease.

  5. Although no CDNF mutations are found in early-onset Parkinson's disease patient samples, a trend towards increased risk for Parkinson's in carriers of the C allele of rs7094179 single nucleotide polymorphism (SNP) is found.

  6. expressed in several tissues; might be beneficial for the treatment of Parkinson's disease

  7. structures of MANF (show MANF Proteins) and CDNF were solved; structure explains why MANF (show MANF Proteins) and CDNF are bifunctional; neurotrophic activity may reside in the N-terminal domain and ER stress response in the C-terminal domain

  8. Study suggests that there is no association between variants in the CDNF gene and cocaine dependence.

Mouse (Murine) Cerebral Dopamine Neurotrophic Factor (CDNF) interaction partners

  1. secretion of mouse MANF (show MANF Proteins) and mouse CDNF is fundamentally regulated in the same manner, the variation of four C-terminal amino acids in the MANF (show MANF Proteins) and CDNF among species might influence their intracellular functions.

  2. This study demonstrated that decrease in mRNA level of CDNF in brain in microgravity.

  3. CDNF (Armetl1) is expressed in several tissues, including the mouse embryonic and postnatal brain

CDNF Protein Profile

Protein Summary

Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.

Gene names and symbols associated with CDNF

  • cerebral dopamine neurotrophic factor (CDNF)
  • cerebral dopamine neurotrophic factor (Cdnf)
  • cerebral dopamine neurotrophic factor-like (LOC100511096)
  • 9330140G23 protein
  • Armetl1 protein

Protein level used designations for CDNF

ARMET-like protein 1 , arginine-rich, mutated in early stage tumors-like 1 , conserved dopamine neurotrophic factor , arginine-rich protein mutated in early stage tumors-like 1

GENE ID SPECIES
441549 Homo sapiens
227526 Mus musculus
361276 Rattus norvegicus
607252 Canis lupus familiaris
513798 Bos taurus
100728228 Cavia porcellus
100511096 Sus scrofa
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