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anti-Ceroid-Lipofuscinosis, Neuronal 3 (CLN3) Antibodies

CLN3 encodes a protein that is involved in lysosomal function. Additionally we are shipping CLN3 Proteins (4) and CLN3 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLN3 12752 Q61124
CLN3 1201 Q13286
CLN3 293485  
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Top anti-CLN3 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB Western Blot analysis of CLN3 expression in transfected 293T cell line by CLN3 monoclonal antibody (M03), clone 1G10. Lane 1: CLN3 transfected lysate(47.623 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Cy7 IF (p)   100 μL Log in to see 14 to 21 Days
$379.50
Details

CLN3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Top referenced anti-CLN3 Antibodies

  1. Human Monoclonal CLN3 Primary Antibody for WB - ABIN393265 : Adams, Beck, Levy, Jordan, Kwon, Marshall, Vierhile, Augustine, de Blieck, Pearce, Mink: Genotype does not predict severity of behavioural phenotype in juvenile neuronal ceroid lipofuscinosis (Batten disease). in Developmental medicine and child neurology 2010 (PubMed)
    Show all 5 references for ABIN393265

More Antibodies against CLN3 Interaction Partners

Mouse (Murine) Ceroid-Lipofuscinosis, Neuronal 3 (CLN3) interaction partners

  1. findings in two distinct lysosome-related degradative pathways constitute the first description of a deficit in the retinal pigment epithelium caused by loss of CLN3

  2. The small GTPase (show RACGAP1 Antibodies) Cdc42 (show CDC42 Antibodies) is misregulated in the absence of CLN3, and thus may be a common link to multiple cellular defects.

  3. Rssults suggested that CLN2 (show TPP1 Antibodies), CLN3 and CLN5 (show CLN5 Antibodies) genes may play an important role in early embryonal neurogenesis.

  4. The aim of our study was to investigate the visual disease progression in the Cln3 (Deltaex7/8) mice.

  5. CLN3 facilitates transport of microdomain-associated proteins.

  6. results demonstrate altered glutamate (show GRIN1 Antibodies) receptor function in Cln3(Deltaex7/8) neurons and suggest that both AMPA (show GRIA3 Antibodies) and NMDA receptors are potential therapeutic targets in juvenile neuronal ceroid lipofuscinosis (show CLN6 Antibodies)

  7. The migration defect in Cln3(-/-) results, in part, from the loss of the CLN3-myosin-IIB (show MYH10 Antibodies) interaction.

  8. Findings suggest an osmoregulated role for CLN3p in renal medullary control of water and K(+) balance.

  9. Cln3(Deltaex7/8) knock-in mice with the common juvenile-onset neuronal ceroid lipofuscinosis (show CLN6 Antibodies) (JNCL; Batten disease) mutation exhibit progressive neurologic disease that begins before birth.

  10. we investigated endogenous Cln3p expression using two peptide antibodies raised against two distinct epitopes of murine Cln3p.

Human Ceroid-Lipofuscinosis, Neuronal 3 (CLN3) interaction partners

  1. CLN3 knockdown inhibits cell proliferation and induces G0/G1 cell cycle arrest in the A2780 cell line and its drug-resistant sub-lines.

  2. The membrane topology of human CLN3 protein.

  3. The eyes and vision of heterozygous carriers of CLN3 disease showed normal features when compared to a control group, which controverts a previously suggested retinal dysfunction in these subjects.

  4. This new model system, which allows for the study of Cln3 function in both single cells and a multicellular organism, together with the observation that expression of human CLN3 restores abnormalities in Dictyostelium cln3- cells

  5. These results further support an important role for the CLN3 protein in intracellular Ca(2 (show CA2 Antibodies)+) handling and in autophagic pathway flux and establish a powerful new platform for therapeutic screening.

  6. CLN3 mutation is associated with neuronal ceroid lipofuscinosis (show CLN6 Antibodies).

  7. Genetic testing for CLN3 should be considered in autophagic vacuolar myopathy (AVM), with autophagic vacuoles and sarcolemmal features.

  8. CLN3 was identified as a novel disease gene for non-syndromic retinal diseases as supported by five unrelated patient families in this study.

  9. CLN3 is involved in the response and adaptation to cellular stress.

  10. Protein interaction mapping analysis suggests CLN3 is involved in transmembrane transport, lipid homeostasis, neuronal excitability and link it to G-protein signaling and protein folding/sorting in the endoplasmic reticulum.

Cow (Bovine) Ceroid-Lipofuscinosis, Neuronal 3 (CLN3) interaction partners

  1. The candidate genes for bovine Neuronal Ceroid Lipofuscinosis (show CLN6 Antibodies), CLN3, CLN5 (show CLN5 Antibodies) and CLN6 (show CLN6 Antibodies), have been mapped to facilitate linkage analysis in cattle and sheep.

CLN3 Antigen Profile

Protein Summary

This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with CLN3

  • ceroid-lipofuscinosis, neuronal 3 (cln3) antibody
  • battenin (PTRG_05620) antibody
  • ceroid-lipofuscinosis, neuronal 3 (CLN3) antibody
  • ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) (Cln3) antibody
  • ceroid-lipofuscinosis, neuronal 3 (Cln3) antibody
  • AI323623 antibody
  • BTS antibody
  • GB12798 antibody
  • JNCL antibody
  • MGC80041 antibody
  • zgc:92244 antibody

Protein level used designations for CLN3

battenin , ceroid-lipofuscinosis, neuronal 3 , ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) , ceroid-lipofuscinosis, neuronal 3, juvenile , battenin-like , batten disease protein , Cln3p , ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)

GENE ID SPECIES
492340 Danio rerio
6343873 Pyrenophora tritici-repentis Pt-1C-BFP
410860 Apis mellifera
446498 Xenopus laevis
467935 Pan troglodytes
739020 Pan troglodytes
100009244 Oryctolagus cuniculus
100124328 Xenopus (Silurana) tropicalis
100127354 Sus scrofa
100388249 Callithrix jacchus
100457403 Pongo abelii
100583151 Nomascus leucogenys
12752 Mus musculus
1201 Homo sapiens
479794 Canis lupus familiaris
504799 Bos taurus
293485 Rattus norvegicus
Selected quality suppliers for anti-CLN3 (CLN3) Antibodies
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