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Chaperonin Containing TCP1, Subunit 5 (Epsilon) Proteins (CCT5)

The protein encoded by CCT5 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). Additionally we are shipping CCT5 Antibodies (61) and CCT5 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCT5 22948 P48643
CCT5 12465 P80316
Rat CCT5 CCT5 294864 Q68FQ0
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Top CCT5 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CCT5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced CCT5 Proteins

  1. Human CCT5 Protein expressed in Wheat germ - ABIN1348519 : Hirai, Maeda, Omori, Yamamoto, Kokeguchi, Takashiba: Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT. in Pathogens and disease 2013 (PubMed)

More Proteins for Chaperonin Containing TCP1, Subunit 5 (Epsilon) (CCT5) Interaction Partners

Human Chaperonin Containing TCP1, Subunit 5 (Epsilon) (CCT5) interaction partners

  1. CCT5 complex caps (show CAPS Proteins) mutant mHTT fibrils at their tips and encapsulates mHTT oligomers, providing a structural description of the inhibition of mHTTQ46-Ex1 (show FRMD6 Proteins) by CCT5 complex and a shared mechanism of mHTT inhibition between TRiC (show MARVELD2 Proteins) chaperonin (show HSPD1 Proteins) and the CCT5 complex

  2. H147R CCT5 was not as efficient in chaperoning these substrates as wild type CCT5.

  3. Both CCT4 (show CCT4 Proteins) and CCT5 homo-oligomers have the property of forming 8-fold double rings absent the other subunits, and these complexes carry out chaperonin (show HSPD1 Proteins) reactions without other partner subunits.

  4. introduction of the truncated human CCT epsilon subunit (show CHRNE Proteins) into yeast cells

  5. A missense mutation within the CCT5 gene is associated with autosomal recessive mutilating sensory neuropathy with spastic paraplegia.

  6. mRNA expression of CCT5, RGS3 (show RGS3 Proteins), and YKT6 (show YKT6 Proteins) was significantly up-regulated in p53 (show TP53 Proteins)-mutated tumors and associated with a low response rate to docetaxel.

CCT5 Protein Profile

Protein Summary

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. In addition, three pseudogenes of this gene have been identified.

Gene names and symbols associated with CCT5

  • chaperonin containing TCP1, subunit 5 (epsilon) (CCT5)
  • chaperonin containing TCP1, subunit 5 (epsilon) (Cct5)
  • chaperonin containing Tcp1, subunit 5 (epsilon) (Cct5)
  • chaperonin containing TCP1, subunit 5 (epsilon) (cct5)
  • Protein CCT-5 (cct-5)
  • CCT-epsilon protein
  • Cct5 protein
  • cct5a protein
  • Ccte protein
  • DKFZp469K0732 protein
  • mKIAA0098 protein
  • TCP-1-epsilon protein
  • TCPE protein
  • wu:fb54h08 protein

Protein level used designations for CCT5

chaperonin containing TCP1, subunit 5 (epsilon) , TCP-1-epsilon , T-complex protein 1 subunit epsilon , T-complex protein 1 subunit epsilon-like , t-complex protein 1 subunit epsilon-like , T-complex protein 1, epsilon subunit , CCT-epsilon , chaperonin subunit 5 (epsilon) , TCP-1 epsilon , chaperonin containing TCP1, subunit 5 (epsilon) a

GENE ID SPECIES
461721 Pan troglodytes
696640 Macaca mulatta
720427 Macaca mulatta
100101123 Felis catus
100169634 Acyrthosiphon pisum
100171594 Pongo abelii
100013512 Monodelphis domestica
100409570 Callithrix jacchus
100483094 Ailuropoda melanoleuca
100070912 Equus caballus
100539807 Meleagris gallopavo
100627652 Sus scrofa
100632800 Amphimedon queenslandica
22948 Homo sapiens
12465 Mus musculus
294864 Rattus norvegicus
322258 Danio rerio
533784 Bos taurus
380145 Xenopus laevis
420930 Gallus gallus
606873 Canis lupus familiaris
175588 Caenorhabditis elegans
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