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Charged Multivesicular Body Protein 4B Proteins (CHMP4B)

CHMP4B encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. Additionally we are shipping CHMP4B Antibodies (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHMP4B 128866 Q9H444
CHMP4B 75608 Q9D8B3
CHMP4B    
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Top CHMP4B Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,548.33
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,570.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

CHMP4B Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Chicken

More Proteins for Charged Multivesicular Body Protein 4B (CHMP4B) Interaction Partners

Human Charged Multivesicular Body Protein 4B (CHMP4B) interaction partners

  1. homologous domain of human Bro1 (show HMGCR Proteins) domain-containing proteins, Alix (show PDCD6IP Proteins) and Brox, binds CHMP4B (show CHMP4A Proteins) but not STAM2 (show STAM2 Proteins), despite their high structural similarity

  2. The ESCRT-III subunit CHMP4B (show CHMP4A Proteins) is a key effector in abscission, whereas its paralogue, CHMP4C (show CHMP4C Proteins), is a component in the abscission checkpoint that delays abscission until chromatin is cleared from the intercellular bridge.

  3. our results implied that CHMP4B (show CHMP4A Proteins) could be a promising prognostic biomarker as well as a potential therapeutic target of HCC (show FAM126A Proteins).

  4. CHMP4B (show CHMP4A Proteins), through its association with chromatin, may participate in the autophagolysosomal degradation of micronuclei and other extranuclear chromatin.

  5. CHMP4B (show CHMP4A Proteins) interacts directly with CC2D1A (show CC2D1A Proteins) and CC2D1B (show CC2D1B Proteins) with nanomolar affinity by forming a 1:1 complex.

  6. CC2D1A (show CC2D1A Proteins) interaction with CHMP4B (show CHMP4A Proteins)/4A blocks HIV-1 budding.

  7. hSnf7-1 and hSnf7-2 are preferentially associated with CHMP2A (show CHMP2A Proteins) and CHMP2B (show CHMP2B Proteins), respectively, and regulate the turnover of distinct transmembrane cargos such as neurotransmitter receptors in human neurons.

  8. CHMP4b (show CHMP4A Proteins) and Alix (show PDCD6IP Proteins) participate in formation of multivesicular bodies by cooperating with SKD1 (show vps4b Proteins)

  9. ALIX (show PDCD6IP Proteins) can have a dramatic effect on HIV-1 release by binding at the CHMP4B (show CHMP4A Proteins) site; the ability to use ALIX (show PDCD6IP Proteins) may allow HIV-1 to replicate in cells that express only low levels of Tsg101 (show TSG101 Proteins)

  10. These data provide the first evidence that CHMP4B (show CHMP4A Proteins) plays a vital role the maintenance of lens transparency.

Mouse (Murine) Charged Multivesicular Body Protein 4B (CHMP4B) interaction partners

  1. CHMP4B, through its association with chromatin, may participate in the autophagolysosomal degradation of micronuclei and other extranuclear chromatin.

CHMP4B Protein Profile

Protein Summary

This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.

Gene names and symbols associated with CHMP4B

  • charged multivesicular body protein 4B (CHMP4B)
  • charged multivesicular body protein 4B (Chmp4b)
  • chromatin modifying protein 4B (CHMP4B)
  • zgc:56112 (zgc:56112)
  • 2010012F05Rik protein
  • C20orf178 protein
  • C76846 protein
  • CHMP4A protein
  • CTPP3 protein
  • CTRCT31 protein
  • dJ553F4.4 protein
  • Shax1 protein
  • SNF7 protein
  • Snf7-2 protein
  • Vps32-2 protein
  • VPS32B protein

Protein level used designations for CHMP4B

SNF7 homolog associated with Alix 1 , Snf7 homologue associated with Alix 1 , charged multivesicular body protein 4b , chromatin modifying protein 4B , chromatin-modifying protein 4b , hSnf7-2 , hVps32-2 , vacuolar protein sorting-associated protein 32-2 , vacuolar protein-sorting-associated protein 32-2 , CHMP4b

GENE ID SPECIES
128866 Homo sapiens
75608 Mus musculus
419150 Gallus gallus
393164 Danio rerio
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