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Charged Multivesicular Body Protein 5 Proteins (CHMP5)

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. Additionally we are shipping CHMP5 Antibodies (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHMP5 51510 Q9NZZ3
CHMP5 76959 Q9D7S9
CHMP5 297995 Q4QQV8
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Top CHMP5 Proteins at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,544.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,544.67
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$2,575.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CHMP5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced CHMP5 Proteins

  1. Human CHMP5 Protein expressed in Escherichia coli (E. coli) - ABIN1098404 : Ward, Vaughn, Shiflett, White, Pollock, Hill, Schnegelberger, Sundquist, Kaplan: The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN1098404

More Proteins for Charged Multivesicular Body Protein 5 (CHMP5) Interaction Partners

Human Charged Multivesicular Body Protein 5 (CHMP5) interaction partners

  1. CHMP5 might be involved in the homeostatic regulation of TCR on the cell surface, presumably through TCR recycling or degradation. Thus CHMP5 is implicated in TCR-mediated signaling.

  2. ESCRT-III protein CHMP5 inhibits LIP5-mediated VPS4 activation by inducing a moderate conformational change within LIP5.

  3. after CHMP5 inhibition, both Granzyme B/Perforin (show PRF1 Proteins) apoptotic pathway and apoptosis-inducing factor (show AIFM1 Proteins)-mediated necrotic pathway were activated, while autophagic pathway was not activated

  4. PNAS-2 was shown to be anti-apoptotic and may participate in leukemogenesis

  5. pnas-2 is specifically up-regulated in acute leukemia patients.

  6. The pnas-2 gene may be closely related with apotosis of arsenic sulfide (show SQRDL Proteins) treated APL (show FASL Proteins) cells.

Mouse (Murine) Charged Multivesicular Body Protein 5 (CHMP5) interaction partners

  1. CHMP5 tunes NF-kappaB (show NFKB1 Proteins) signaling downstream of RANK in osteoclasts to dampen osteoclast differentiation, osteoblast coupling and bone turnover rates.

  2. CHMP5 regulates late endosome function downstream of MVB formation, and the loss of CHMP5 enhances signal transduction by inhibiting lysosomal degradation of activated receptors.

CHMP5 Protein Profile

Protein Summary

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006

Gene names and symbols associated with CHMP5

  • charged multivesicular body protein 5 (chmp5-b)
  • charged multivesicular body protein 5b (chmp5b)
  • charged multivesicular body protein 5 (CHMP5)
  • charged multivesicular body protein 5 (chmp5-a)
  • charged multivesicular body protein 5 (chmp5)
  • chromatin modifying protein 5 (chmp5)
  • chromatin modifying protein 5 (LOC100345211)
  • charged multivesicular body protein 5 (Chmp5)
  • 2210412K09Rik protein
  • AW545668 protein
  • C9orf83 protein
  • cgi-34 protein
  • chmp5 protein
  • HSPC177 protein
  • PNAS-2 protein
  • RGD1305968 protein
  • SNF7DC2 protein
  • Vps60 protein
  • zgc:64125 protein

Protein level used designations for CHMP5

chromatin modifying protein 5 , charged multivesicular body protein 5 , chromatin-modifying protein 5 , Chromatin-modifying protein 5 , Charged multivesicular body protein 5 , SNF7 domain containing 2 , SNF7 domain-containing protein 2 , apoptosis-related protein PNAS-2 , hVps60 , vacuolar protein sorting-associated protein 60 , likely ortholog of H. sapiens SNF7 domain containing 2

GENE ID SPECIES
380303 Xenopus laevis
393351 Danio rerio
420968 Gallus gallus
446761 Xenopus laevis
549502 Xenopus (Silurana) tropicalis
703191 Macaca mulatta
746713 Pan troglodytes
100172361 Pongo abelii
100305259 Oncorhynchus mykiss
100345211 Oryctolagus cuniculus
100528648 Ictalurus punctatus
51510 Homo sapiens
539781 Bos taurus
76959 Mus musculus
297995 Rattus norvegicus
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