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Chemokine (C-C Motif) Ligand 17 Proteins (CCL17)

CCL17 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Additionally we are shipping CCL17 Antibodies (145) and CCL17 Kits (71) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCL17 6361 Q92583
CCL17 20295  
CCL17 117518  
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Top CCL17 Proteins at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 4 pack Log in to see 10 to 12 Days
$86.96
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$103.27
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$114.15
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$795.30
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$827.20
Details

CCL17 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) , ,
,
Rat (Rattus)

Top referenced CCL17 Proteins

  1. Mouse (Murine) CCL17 Protein expressed in Escherichia coli (E. coli) - ABIN2666602 : Stutte, Quast, Gerbitzki, Savinko, Novak, Reifenberger, Homey, Kolanus, Alenius, Förster: Requirement of CCL17 for CCR7- and CXCR4-dependent migration of cutaneous dendritic cells. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 6 references for ABIN2666602

  2. Human CCL17 Protein expressed in Escherichia coli (E. coli) - ABIN2667385 : Oo, Weston, Lalor, Curbishley, Withers, Reynolds, Shetty, Harki, Shaw, Eksteen, Hubscher, Walker, Adams: Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 5 references for ABIN2667385

  3. Human CCL17 Protein expressed in Escherichia coli (E. coli) - ABIN2666600 : Yogo, Fujishima, Inoue, Saito, Shiomi, Yamaguchi, Ishizaka: Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis. in Respiratory research 2009 (PubMed)
    Show all 5 references for ABIN2666600

  4. Human CCL17 Protein expressed in Escherichia coli (E. coli) - ABIN666786 : Imai, Yoshida, Baba, Nishimura, Kakizaki, Yoshie: Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector. in The Journal of biological chemistry 1996 (PubMed)
    Show all 2 references for ABIN666786

More Proteins for Chemokine (C-C Motif) Ligand 17 (CCL17) Interaction Partners

Human Chemokine (C-C Motif) Ligand 17 (CCL17) interaction partners

  1. CCL17 positively regulates the tumorigenesis of hepatocellular carcinoma.Higher levels of intratumoral CCL17 expression are associated with poorer survival of hepatocellular carcinoma patients.

  2. CCL17 and CCL18 (show CCL18 Proteins) dermal expression is associated with leprosy polarity.

  3. The SNP rs223895 in TARC/CCL17 gene is associated with the susceptibility to Kawasaki disease.

  4. Serum CCL17 levels are associated with coronary artery disease and atherosclerosis severity independently of traditional cardiovascular risk factors.

  5. TARC was correlated with disease status and its monitoring may be able to predict PET positivity after alloSCT, thus potentially allowing an early immune manipulation.

  6. Serum levels of CCL17 were positively correlated with coronary artery disease.

  7. TARC and interleukin-31 (show IL31 Proteins) may be biomarkers for adult atopic dermatitis

  8. Serum TARC is a promising biomarker for remission and can be used for accurately monitoring proactive treatment for long-term control. [revew]

  9. High CXCL10 (show CXCL10 Proteins) levels were detected in acutely infected children regardless of virus pathogen, whereas increased CCL17 production was RSV-specific

  10. Higher serum concentrations of CCL17 at baseline may be predictive of acute exacerbations in patients with chronic hypersensitivity pneumonitis

Mouse (Murine) Chemokine (C-C Motif) Ligand 17 (CCL17) interaction partners

  1. Aged mice had similar levels of IL-1beta (show IL1B Proteins), TNF (show TNF Proteins), IFN-gamma (show IFNG Proteins), IL-17 (show IL17A Proteins), and granulocyte colony-stimulating factor (show CSF3 Proteins) following S. pneumoniae infection, compared with young mice, but increased levels of the chemokines CXCL9 (show CXCL9 Proteins), CXCL12 (show CXCL12 Proteins), CCL3 (show CCL3 Proteins), CCL4 (show CCL4 Proteins), CCL5 (show CCL5 Proteins), CCL11, and CCL17.

  2. that effective engagement of CCR4 (show CCR4 Proteins) by CCL17 involves two distinct binding domains and interaction with both is required for signaling

  3. murine tumor-associated neutrophils secrete significant amounts of CCL17. Migration assays showed recruitment of T-regs by tumor-associated neutrophils, which was inhibited with anti-CCL17 monoclonal antibodies.

  4. TSLP (show TSLP Proteins) activated a subset of CD11b (show ITGAM Proteins)(+) DCs in the skin to produce CCL17, upregulate CCR7 (show CCR7 Proteins), and migrate to the draining lymph node to initiate Th2 differentiation.

  5. CCL17 is required for induction of intestinal inflammation in mice and has an autocrine effect on dendritic cells that promotes production of inflammatory cytokines and activation of Th1 (show HAND1 Proteins) and Th17 cells and reduces expansion of Treg cells.

  6. Kinetics of CCL17 mRNA expression in an allergic contact dermatitis model.

  7. Thymus and activation-regulated chemokine (TARC)/CC chemokine (show CCL1 Proteins) ligand (CCL) 17 accelerates wound healing by enhancing fibroblast migration.

  8. Data identify DC-derived CCL17 as a central regulator of Treg homeostasis, implicate DCs and their effector functions in atherogenesis, and suggest that CCL17 might be a target for vascular therapy.

  9. Data show that mice deficient for CCL17 had an up to 4-fold higher worm burden compared with controls by day 10 of infection with the murine filaria Litomosoides sigmodontis.

  10. The inducible chemokine (show CCL1 Proteins) CCL17 sensitizes dendritic cells (DCs) for CCR7 (show CCR7 Proteins)- and CXCR4 (show CXCR4 Proteins)-dependent migration to lymph node-associated homeostatic chemokines under inflammatory conditions and thus plays an important role in cutaneous DC migration.

CCL17 Protein Profile

Protein Summary

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Gene names and symbols associated with CCL17

  • chemokine (C-C motif) ligand 17 (CCL17)
  • chemokine (C-C motif) ligand 17 (Ccl17)
  • A-152E5.3 protein
  • Abcd-2 protein
  • CCL17 protein
  • Scya17 protein
  • Scya17l protein
  • Tarc protein

Protein level used designations for CCL17

chemokine (C-C motif) ligand 17 , C-C motif chemokine 17 , CC chemokine TARC , T cell-directed CC chemokine , small inducible cytokine subfamily A (Cys-Cys), member 17 , small-inducible cytokine A17 , thymus and activation-regulated chemokine , small inducible cytokine subfamily A17 , chemokine ligand 17-like protein , chemokine CCL17/TARC , small inducible cytokine A17

GENE ID SPECIES
467985 Pan troglodytes
6361 Homo sapiens
20295 Mus musculus
493832 Felis catus
100140488 Bos taurus
403586 Canis lupus familiaris
415652 Gallus gallus
100715805 Cavia porcellus
780408 Sus scrofa
117518 Rattus norvegicus
101120186 Ovis aries
574180 Macaca mulatta
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