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anti-Chemokine (C-C Motif) Ligand 21 (CCL21) Antibodies

CCL21 is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Additionally we are shipping CCL21 Proteins (55) and CCL21 Kits (44) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCL21 6366 O00585
CCL21 65956 P86792 , P86793
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Top anti-CCL21 Antibodies at

Showing 10 out of 160 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB CCL21 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CCL21 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. CCL21 Antibody (Center) western blot analysis in 293 cell line lysates (35µg/lane).This demonstrates the CCL21 antibody detected the CCL21 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Mouse Rat Un-conjugated ELISA (Capture), FACS, IHC, WB Detection of CCL21/6Ckine in D3 Mouse Cell Line by Flow Cytometry. D3 mouse embryonic stem cell line was stained with Rat Anti-Mouse CCL21/6Ckine Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. CCL21/6Ckine in Mouse Thymus. CCL21/6Ckine was detected in perfusion fixed frozen sections of mouse thymus using Mouse CCL21/6Ckine Monoclonal Antibody. Specific staining was localized to endothelial cells. 100 μg Log in to see 6 to 7 Days
Mouse Goat Un-conjugated FACS, IHC, Neut, WB 100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse foot tumor labeled with Anti-CCL21/6CKINE Polyclonal Antibody, Unconjugated (ABIN732698) followed by conjugation to the secondary antibody and DAB staining Raji lysates probed with Rabbit Anti-CCL21/6Ckine Polyclonal Antibody  at 1:5000 90min in 37˚C 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated IHC (p), WB CCL21 Antibody (Center) (ABIN654093) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated EIA, Func, WB   50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: CCL21/6Ckine Antibody [NBP2-37928] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: RT-4.Lane 3: U-251 MG.Lane 4: Human Plasma.Lane 5: Liver.Lane 6: Tonsil Immunohistochemistry: CCL21/6Ckine Antibody [NBP2-37928] - Staining of human lymph node shows distinct positivity in a subset of vessels. 0.1 mL Log in to see 8 to 11 Days
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded human stomach using CCL21 antibody at dilution of 1:100 (40x lens). 100 μL Log in to see 14 Days
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Biotin EIA, WB   25 μg Log in to see 6 to 8 Days

CCL21 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) , , ,
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Top referenced anti-CCL21 Antibodies

  1. Mouse (Murine) Polyclonal CCL21 Primary Antibody for FACS, IHC - ABIN4899786 : Eberlein, Nguyen, Victorino, Golden-Mason, Rosen, Homann: Comprehensive assessment of chemokine expression profiles by flow cytometry. in The Journal of clinical investigation 2010 (PubMed)
    Show all 25 references for ABIN4899786

  2. Mouse (Murine) Monoclonal CCL21 Primary Antibody for ELISA (Capture), FACS - ABIN4899784 : Tolba, Bowers, Muller, Housekneckt, Giuliano, Federoff, Rosenblatt: Herpes simplex virus (HSV) amplicon-mediated codelivery of secondary lymphoid tissue chemokine and CD40L results in augmented antitumor activity. in Cancer research 2002 (PubMed)
    Show all 4 references for ABIN4899784

  3. Human Polyclonal CCL21 Primary Antibody for EIA, IHC (p) - ABIN950189 : Rey-Gallardo, Escribano, Delgado-Martín, Rodriguez-Fernández, Gerardy-Schahn, Rutishauser, Corbi, Vega: Polysialylated neuropilin-2 enhances human dendritic cell migration through the basic C-terminal region of CCL21. in Glycobiology 2010 (PubMed)
    Show all 4 references for ABIN950189

  4. Human Polyclonal CCL21 Primary Antibody for EIA, Func - ABIN116001 : Steiniger, Rüttinger, Barth: The three-dimensional structure of human splenic white pulp compartments. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003 (PubMed)
    Show all 2 references for ABIN116001

  5. Human Polyclonal CCL21 Primary Antibody for IHC, IHC (p) - ABIN4288804 : Andersson, Nilsson, Fagerberg, Hallström, Sundström, Danielsson, Edlund, Uhlen, Asplund: The transcriptomic and proteomic landscapes of bone marrow and secondary lymphoid tissues. in PLoS ONE 2014 (PubMed)

  6. Human Polyclonal CCL21 Primary Antibody for IF (p), IHC (p) - ABIN732698 : Borrelli, Abrão, Taube, Darb-Esfahani, Köhler, Kaufmann, Chiantera, Mechsner: Immunohistochemical Investigation of Metastasis-Related Chemokines in Deep-Infiltrating Endometriosis and Compromised Pelvic Sentinel Lymph Nodes. in Reproductive sciences (Thousand Oaks, Calif.) 2015 (PubMed)

More Antibodies against CCL21 Interaction Partners

Human Chemokine (C-C Motif) Ligand 21 (CCL21) interaction partners

  1. CCL21 can facilitate chemoresistance and stem cell property of colorectal cancer cells via the upregulation of P-gp (show ABCB4 Antibodies), Bmi-1 (show BMI1 Antibodies), Nanog (show NANOG Antibodies), and OCT-4 (show POU5F1 Antibodies) through AKT (show AKT1 Antibodies)/GSK-3beta (show GSK3b Antibodies)/Snail (show SNAI1 Antibodies) signals.

  2. CCL21/CCR7 (show CCR7 Antibodies) induce VEGF-D (show Figf Antibodies) up-regulation and promote lymphangiogenesis via ERK (show EPHB2 Antibodies)/Akt (show AKT1 Antibodies) pathway in lung cancer.

  3. Our findings suggested that MUC1 (show MUC1 Antibodies) plays an important role in CCL21-CCR7 (show CCR7 Antibodies)-induced lymphatic metastasis and may serve as a therapeutic target in esophageal squamous cell carcinoma .

  4. TGF-beta1 (show TGFB1 Antibodies) promoted CCL21 expression in lymphatic endothelial cells. CCL21 acted in a paracrine fashion to mediate chemotactic migration of EMT (show ITK Antibodies) cells toward lymphatic endothelial cells.

  5. The chemotactic interaction between CCR7 (show CCR7 Antibodies) and its ligand, CCL21, may be a critical event during progression in pancreatic cancer

  6. CCL21 gene SNP (rs951005) might confer genetic predisposition to polymyositis patients or such patients with interstitial lung disease in a Chinese Han population.

  7. over-expression of CCL21 could increased the expressions of antigen presentation-related genes in CK8 (show KRT8 Antibodies)/18 TECs in MG patients

  8. Priming by CCL21 restricts lateral mobility of the adhesion receptor LFA-1 (show ITGAL Antibodies) and restores adhesion to ICAM-1 (show ICAM1 Antibodies) nanoaggregates on human mature dendritic cells.

  9. CCL21/CCR7 (show CCR7 Antibodies) pathway activates signallings to up-regulate Slug (show SNAI2 Antibodies) pathway, leading to the occurrence of epithelial-mesenchymal transition process in human chondrosarcoma

  10. These results reveal that CCR7 (show CCR7 Antibodies) and VEGF-C (show VEGFC Antibodies) display a significant crosstalk and suggest a novel role of the CCL21/CCR7 (show CCR7 Antibodies) chemokine (show CCL1 Antibodies) axis in the promotion of breast cancer-induced lymphangiogenesis.

Mouse (Murine) Chemokine (C-C Motif) Ligand 21 (CCL21) interaction partners

  1. the CCR7 (show CCR7 Antibodies)/CCL21 signaling pathway leading to T lymphocyte migration on fibronectin (show FN1 Antibodies) is a beta1 integrin-dependent pathway involving transient ERK1/2 (show MAPK1/3 Antibodies) phosphorylation, which is modulated by PLCgamma1 (show PLCG1 Antibodies)

  2. Data suggest that lymphotoxin (show LTB Antibodies)-dependent and -independent regulation of CC chemokine ligand 21-b and -c plays a role in balancing the central and peripheral immune responses between lymphoid and nonlymphoid tissues.

  3. CCL21 and, to a lesser extent, CCL19 (show CCL19 Antibodies) play significant roles in the distinctive localization of marginal zone macrophages within the splenic marginal zone.

  4. CCL21 and 5'-Nase may be involved in the interaction between infiltrating cells and lymphatic vessels to induce the functional changes of lymphatic endothelial cells during insulitic and diabetic development

  5. CXCL9 (show CXCL9 Antibodies) has a role in graft rejection in the absence of CCL19 (show CCL19 Antibodies) and CCL21

  6. T-cell defects in the nasal-associated lymphoid tissue of lymphotoxin (show LTB Antibodies)(-/-) mice can be attributed to the impaired expression of CCL21.

  7. alpha-GalCer-loaded dendritic cells expressing tumor-associated antigen along with SLC (show CCL21A Antibodies) can stimulate multiple subsets of effector cells to induce a potent therapeutic effect against peritoneally disseminated tumor cells.

  8. following Leishmania donovani infection of mice, the migration of splenic DC is regulated by the CCR7 (show CCR7 Antibodies) ligands CCL19 (show CCL19 Antibodies)/CCL21

  9. Results suggest that CCR7 (show CCR7 Antibodies)-positive fibrocytes infiltrate the kidney via CCL21-positive vessels, thereby contributing to the pathogenesis of renal fibrosis.

  10. The presence of CCL21 during the in vitro stimulation of CD4 (show CD4 Antibodies)+ T cells with anti-CD3 (show CD3E Antibodies) plus anti-CD28 (show CD28 Antibodies) significantly enhanced in vitro AICD induction of the restimulated T cells, partially through enhancing expression of Fas ligand (show FASL Antibodies).

CCL21 Antigen Profile

Protein Summary

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Gene names and symbols associated with CCL21

  • chemokine (C-C motif) ligand 21 (CCL21) antibody
  • CCL21 (SLC) antibody
  • C-C motif chemokine 21 (ccl21) antibody
  • small inducible cytokine A24 (LOC100354652) antibody
  • chemokine (C-C motif) ligand 21C (leucine) (Ccl21c) antibody
  • 6Ckine antibody
  • ccl21 antibody
  • Ccl21b antibody
  • CKb9 antibody
  • ECL antibody
  • exodus-2 antibody
  • Scya21 antibody
  • Scya21b antibody
  • Scya21c antibody
  • SLC antibody
  • TCA4 antibody

Protein level used designations for CCL21

C-C motif chemokine 21 , CC chemokine ligand 21 , putative CCL21 chemokine , small inducible cytokine A21 , CCL21 , small inducible cytokine A24 , Efficient Chemoattractant for Lymphocytes , beta chemokine exodus-2 , secondary lymphoid tissue chemokine , small inducible cytokine subfamily A (Cys-Cys), member 21 , chemokine CCL21/6CKINE , small-inducible cytokine A21 , C-C motif chemokine 21b , C-C motif chemokine 21c , Ccl21-leu , Small-inducible cytokine A21b , beta-chemokine exodus-2 , small inducible cytokine A21c , small-inducible cytokine A21c , thymus-derived chemotactic agent 4

448796 Canis lupus familiaris
448797 Sus scrofa
511112 Bos taurus
746205 Pan troglodytes
100144337 Oryctolagus cuniculus
100196238 Salmo salar
100354652 Oryctolagus cuniculus
6366 Homo sapiens
574183 Macaca mulatta
65956 Mus musculus
Selected quality suppliers for anti-CCL21 (CCL21) Antibodies
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