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CCL21 is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Additionally we are shipping CCL21 Proteins (52) and CCL21 Kits (42) and many more products for this protein.
Showing 10 out of 159 products:
Human Polyclonal CCL21 Primary Antibody for EIA, IHC (p) - ABIN950189
Rey-Gallardo, Escribano, Delgado-Martín, Rodriguez-Fernández, Gerardy-Schahn, Rutishauser, Corbi, Vega: Polysialylated neuropilin-2 enhances human dendritic cell migration through the basic C-terminal region of CCL21. in Glycobiology 2010
Show all 4 references for ABIN950189
Human Polyclonal CCL21 Primary Antibody for EIA, Func - ABIN116001
Steiniger, Rüttinger, Barth: The three-dimensional structure of human splenic white pulp compartments. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003
Show all 2 references for ABIN116001
Human Polyclonal CCL21 Primary Antibody for IF (p), IHC (p) - ABIN732698
Borrelli, Abrão, Taube, Darb-Esfahani, Köhler, Kaufmann, Chiantera, Mechsner: Immunohistochemical Investigation of Metastasis-Related Chemokines in Deep-Infiltrating Endometriosis and Compromised Pelvic Sentinel Lymph Nodes. in Reproductive sciences (Thousand Oaks, Calif.) 2015
CCL21 can facilitate chemoresistance and stem cell property of colorectal cancer cells via the upregulation of P-gp (show ABCB4 Antibodies), Bmi-1 (show BMI1 Antibodies), Nanog (show NANOG Antibodies), and OCT-4 (show POU5F1 Antibodies) through AKT (show AKT1 Antibodies)/GSK-3beta (show GSK3b Antibodies)/Snail (show SNAI1 Antibodies) signals.
CCL21/CCR7 (show CCR7 Antibodies) induce VEGF-D (show Figf Antibodies) up-regulation and promote lymphangiogenesis via ERK (show EPHB2 Antibodies)/Akt (show AKT1 Antibodies) pathway in lung cancer.
Our findings suggested that MUC1 (show MUC1 Antibodies) plays an important role in CCL21-CCR7 (show CCR7 Antibodies)-induced lymphatic metastasis and may serve as a therapeutic target in esophageal squamous cell carcinoma .
TGF-beta1 (show TGFB1 Antibodies) promoted CCL21 expression in lymphatic endothelial cells. CCL21 acted in a paracrine fashion to mediate chemotactic migration of EMT (show ITK Antibodies) cells toward lymphatic endothelial cells.
The chemotactic interaction between CCR7 (show CCR7 Antibodies) and its ligand, CCL21, may be a critical event during progression in pancreatic cancer
CCL21 gene SNP (rs951005) might confer genetic predisposition to polymyositis patients or such patients with interstitial lung disease in a Chinese Han population.
over-expression of CCL21 could increased the expressions of antigen presentation-related genes in CK8 (show KRT8 Antibodies)/18 TECs in MG patients
Priming by CCL21 restricts lateral mobility of the adhesion receptor LFA-1 (show ITGAL Antibodies) and restores adhesion to ICAM-1 (show ICAM1 Antibodies) nanoaggregates on human mature dendritic cells.
CCL21/CCR7 (show CCR7 Antibodies) pathway activates signallings to up-regulate Slug (show SNAI2 Antibodies) pathway, leading to the occurrence of epithelial-mesenchymal transition process in human chondrosarcoma
These results reveal that CCR7 (show CCR7 Antibodies) and VEGF-C (show VEGFC Antibodies) display a significant crosstalk and suggest a novel role of the CCL21/CCR7 (show CCR7 Antibodies) chemokine (show CCL1 Antibodies) axis in the promotion of breast cancer-induced lymphangiogenesis.
the CCR7 (show CCR7 Antibodies)/CCL21 signaling pathway leading to T lymphocyte migration on fibronectin (show FN1 Antibodies) is a beta1 integrin-dependent pathway involving transient ERK1/2 (show MAPK1/3 Antibodies) phosphorylation, which is modulated by PLCgamma1 (show PLCG1 Antibodies)
Data suggest that lymphotoxin (show LTB Antibodies)-dependent and -independent regulation of CC chemokine ligand 21-b and -c plays a role in balancing the central and peripheral immune responses between lymphoid and nonlymphoid tissues.
CCL21 and, to a lesser extent, CCL19 (show CCL19 Antibodies) play significant roles in the distinctive localization of marginal zone macrophages within the splenic marginal zone.
CCL21 and 5'-Nase may be involved in the interaction between infiltrating cells and lymphatic vessels to induce the functional changes of lymphatic endothelial cells during insulitic and diabetic development
CXCL9 (show CXCL9 Antibodies) has a role in graft rejection in the absence of CCL19 (show CCL19 Antibodies) and CCL21
T-cell defects in the nasal-associated lymphoid tissue of lymphotoxin (show LTB Antibodies)(-/-) mice can be attributed to the impaired expression of CCL21.
alpha-GalCer-loaded dendritic cells expressing tumor-associated antigen along with SLC (show CCL21A Antibodies) can stimulate multiple subsets of effector cells to induce a potent therapeutic effect against peritoneally disseminated tumor cells.
following Leishmania donovani infection of mice, the migration of splenic DC is regulated by the CCR7 (show CCR7 Antibodies) ligands CCL19 (show CCL19 Antibodies)/CCL21
Results suggest that CCR7 (show CCR7 Antibodies)-positive fibrocytes infiltrate the kidney via CCL21-positive vessels, thereby contributing to the pathogenesis of renal fibrosis.
The presence of CCL21 during the in vitro stimulation of CD4 (show CD4 Antibodies)+ T cells with anti-CD3 (show CD3E Antibodies) plus anti-CD28 (show CD28 Antibodies) significantly enhanced in vitro AICD induction of the restimulated T cells, partially through enhancing expression of Fas ligand (show FASL Antibodies).
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
C-C motif chemokine 21
, CC chemokine ligand 21
, putative CCL21 chemokine
, small inducible cytokine A21
, small inducible cytokine A24
, Efficient Chemoattractant for Lymphocytes
, beta chemokine exodus-2
, secondary lymphoid tissue chemokine
, small inducible cytokine subfamily A (Cys-Cys), member 21
, chemokine CCL21/6CKINE
, small-inducible cytokine A21
, C-C motif chemokine 21b
, C-C motif chemokine 21c
, Small-inducible cytokine A21b
, beta-chemokine exodus-2
, small inducible cytokine A21c
, small-inducible cytokine A21c
, thymus-derived chemotactic agent 4