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Chemokine (C-C Motif) Ligand 22 Proteins (CCL22)

CCL22 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Additionally we are shipping CCL22 Antibodies (184) and CCL22 Kits (103) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCL22 6367 O00626
CCL22 117551  
CCL22 20299 O88430
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Top CCL22 Proteins at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse Un-conjugated 25 μg Log in to see 10 to 12 Days
$233.72
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 25 μg Log in to see 10 to 12 Days
$233.72
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 2 to 3 Days
$630.00
Details

CCL22 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Rat (Rattus)

Mouse (Murine) ,
,

Top referenced CCL22 Proteins

  1. Mouse (Murine) CCL22 Protein expressed in Insect Cells - ABIN2666613 : Schaniel, Pardali, Sallusto, Speletas, Ruedl, Shimizu, Seidl, Andersson, Melchers, Rolink, Sideras: Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells. in The Journal of experimental medicine 1998 (PubMed)
    Show all 7 references for ABIN2666613

  2. Human CCL22 Protein expressed in Escherichia coli (E. coli) - ABIN2666894 : Godiska, Chantry, Raport, Sozzani, Allavena, Leviten, Mantovani, Gray: Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. in The Journal of experimental medicine 1997 (PubMed)
    Show all 6 references for ABIN2666894

  3. Human CCL22 Protein expressed in Escherichia coli (E. coli) - ABIN666666 : Mantovani, Gray, Van Damme, Sozzani: Macrophage-derived chemokine (MDC). in Journal of leukocyte biology 2000 (PubMed)
    Show all 2 references for ABIN666666

  4. Human CCL22 Protein expressed in Escherichia coli (E. coli) - ABIN2002214 : Vulcano, Albanesi, Stoppacciaro, Bagnati, DAmico, Struyf, Transidico, Bonecchi, Del Prete, Allavena, Ruco, Chiabrando, Girolomoni, Mantovani, Sozzani: Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo. in European journal of immunology 2001 (PubMed)

More Proteins for Chemokine (C-C Motif) Ligand 22 (CCL22) Interaction Partners

Human Chemokine (C-C Motif) Ligand 22 (CCL22) interaction partners

  1. Our results demonstrate that CCL22 is expressed in human placenta. Decidual expression was only observed in miscarriage conditions and correlates with Treg infiltration.

  2. Distinctive Treg associated CCR4 (show CCR4 Proteins)-CCL22 expression profile with altered frequency of Th17/Treg cell in the immunopathogenesis of Pemphigus Vulgaris (show DSG3 Proteins).

  3. type I IFN blocks the regulatory T cell-attracting chemokine (show CCL1 Proteins) CCL22 and thus helps limit the recruitment of regulatory T cells to tumors

  4. First-episode psychosis patients had higher serum CCL22, which decreased substantially following antipsychotic treatment.

  5. Elevated levels of CCL22 found in the ascites could create a chemokine (show CCL1 Proteins) gradient aiding in Treg cells migration. Increased Tregs percentage in the local microenvironment of ovarian cancer might be an important mechanism of immunosuppression.

  6. Circulating CCL22 levels are related to both glioma risk and survival duration independent of age, histology, grade and IDH (show IDH1 Proteins) mutation status. CCL22 should be considered a marker of immune status with potential prognostic value

  7. CCL22 is a novel mediator of lung inflammation following hemorrhage and resuscitation

  8. CCR4 (show CCR4 Proteins) C1014T and CCL22 C16A genetic variations were neither associated with the risk, nor with the progression of colorectal cancer in Iranian population

  9. The serum CCL22 levels were affected by genetic variations at SNP rs223818. Accordingly, SNP rs223818 may play a role in the susceptibility to breast cancer.

  10. Sesamin suppressed lipopolysaccharide induced CCL22 expression in monocytes through the ER/PPAR (show PPARA Proteins)-a, the MAPK-p38 (show MAPK1 Proteins) pathway, the NFkB-p65 (show GORASP1 Proteins) pathway and the epigenetic regulation by suppressing histone H3 (show HIST3H3 Proteins)/H4 acetylation in the CCL22 promoter region.

Mouse (Murine) Chemokine (C-C Motif) Ligand 22 (CCL22) interaction partners

  1. CCL22-specific antibodies reveal that engagement of two distinct binding domains on CCL22 is required for CCR4 (show CCR4 Proteins)-mediated function.

  2. CCL22 was localised mainly on the cell surface and or in the cytoplasm. Within sections of omental milky spot micrometastases, CCR4 (show CCR4 Proteins) was recognised on or in gastric cancer cells, constituent cells milky spots, blood cells and blood endothelial cells

  3. results show that the IL-4 (show IL4 Proteins)/CCL22/CCR4 (show CCR4 Proteins) axis is involved in the migration of Tregs to osteolytic lesion sites, and attenuates development of lesions by inhibiting inflammatory migration and the production of proinflammatory and osteoclastogenic mediators

  4. CCL22 has a role in Treg skin homing to suppress depigmentation

  5. CCL22 is a novel mediator of lung inflammation following hemorrhage and resuscitation

  6. The immunomodulatory properties of CCL22 could be harnessed for prevention of graft rejection and type 1 diabetes as well as other autoimmune disorders.

  7. Data indicate macrophage-derived chemokine CCL22 as an adjuvant could enhance the immune protective effect of NTHi-P6 protein vaccine to an extent.

  8. islet expression of CCL22 recruits Tregs and attenuates autoimmune destruction of beta cell

  9. Data show that the presence of the Ccr4 (show CCR4 Proteins) and Ccl22 transcripts were detected in brain slices.

  10. These results suggest that CCL22 functions to regulate development of experimental autoimmune encephalomyelitis through macrophage chemoattraction and effector function.

CCL22 Protein Profile

Protein Summary

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.

Gene names and symbols associated with CCL22

  • chemokine (C-C motif) ligand 22 (CCL22)
  • chemokine (C-C motif) ligand 22 (Ccl22)
  • ABCD-1 protein
  • CCL22 protein
  • DC/B-CK protein
  • DCBCK protein
  • Mdc protein
  • Scya22 protein
  • STCP-1 protein

Protein level used designations for CCL22

chemokine (C-C motif) ligand 22 , C-C motif chemokine 22 , CC chemokine STCP-1 , MDC(1-69) , macrophage-derived chemokine , small inducible cytokine A22 , small inducible cytokine subfamily A (Cys-Cys), member 22 , small-inducible cytokine A22 , stimulated T cell chemotactic protein 1 , stimulated T-cell chemotactic protein 1 , small inducible cytokine subfamily A (Cys-Cys) member 22 , CC chemokine ABCD-1 , SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED) , activated B and dendritic cell-derived , dendritic cell and B cell derived chemokine , small inducible cytokine subfamily A, member 22 , small inducible cytokine subfamily A22

GENE ID SPECIES
736543 Pan troglodytes
6367 Homo sapiens
117551 Rattus norvegicus
20299 Mus musculus
616996 Bos taurus
100686212 Canis lupus familiaris
100716085 Cavia porcellus
100516016 Sus scrofa
101123141 Ovis aries
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