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Chemokine (C-C Motif) Ligand 4 Proteins (CCL4)

CCL4 is one of several cytokine genes clustered on the q-arm of chromosome 17. Additionally we are shipping CCL4 Antibodies (225) and CCL4 Kits (88) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCL4 116637 P50230
CCL4 6351 P13236
CCL4 20303 P14097
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Top CCL4 Proteins at antibodies-online.com

Showing 10 out of 72 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 4 to 6 Days
$412.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 100 μg Log in to see 4 to 6 Days
$412.50
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$201.11
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$201.11
Details
HOST_Escherichia coli (E. coli) Mouse His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   20 μg Log in to see 2 to 3 Days
$245.70
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$809.60
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details

CCL4 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus) ,

Human , , ,
, ,
Mouse (Murine)

Top referenced CCL4 Proteins

  1. Mouse (Murine) CCL4 Protein expressed in Escherichia coli (E. coli) - ABIN2666733 : Chandrasekar, Deobagkar-Lele, Victor, Nandi: Regulation of chemokines, CCL3 and CCL4, by interferon γ and nitric oxide synthase 2 in mouse macrophages and during Salmonella enterica serovar typhimurium infection. in The Journal of infectious diseases 2013 (PubMed)
    Show all 9 references for ABIN2666733

  2. Human CCL4 Protein expressed in Escherichia coli (E. coli) - ABIN2666731 : Raport, Gosling, Schweickart, Gray, Charo: Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha. in The Journal of biological chemistry 1996 (PubMed)
    Show all 9 references for ABIN2666731

More Proteins for Chemokine (C-C Motif) Ligand 4 (CCL4) Interaction Partners

Human Chemokine (C-C Motif) Ligand 4 (CCL4) interaction partners

  1. clinical samples, confirmed TB and non-TB (i.e. other respiratory diseases (ORD)) cases, were collected and analyzed simultaneously with quality control (QC) human IP-10 (show CXCL10 Proteins) or CCL4 standards

  2. Report use of up-converting phosphor reporter technology in a lateral flow based test to determine CCL4 levels in pleural effusions and whole blood for tuberculosis diagnosis.

  3. YY1 (show YY1 Proteins) regulates lung CCL4 transcription in pulmonary tuberculosis.

  4. High serum IL-12 (show IL12A Proteins) levels associated with increased densities of peritumoral CD8 (show CD8A Proteins)(+) T cells, intraepithelial CD3 (show CD3 Proteins)(+) T cells and intratumoral neutrophils, while high serum CCL4 levels associated with increased densities of peritumoral CD68 (show CD68 Proteins)(+) cells

  5. Tregs from subjects with established type 1 diabetes were impaired in their ability to produce CCL3 (show CCL3 Proteins) and CCL4.

  6. MIP-1beta, TNF-alpha (show TNF Proteins) and fractalkine (show CX3CL1 Proteins) are expressed in plasma, which reflects the levels of several pro-atherogenic cytokines in plaque tissue

  7. CXCL13 (show CXCL13 Proteins) and CCL4 could act as circulating biomarkers in autoimmune hemolytic anemia (AIHA), and higher plasma soluble TNFRII (show TNFRSF1B Proteins) might favor the diagnosis of SLE-related instead of primary AIHA.

  8. Findings demonstrated that miR (show MLXIP Proteins)-125b is a negative regulator of CCL4 and its reduction is partially responsible for the age-related increase of CCL4.

  9. we found that Brachyury (show TBX1 Proteins) expression was inversely correlated with CCL2 (show CCL2 Proteins) and CCL4 expression in human lung tumors

  10. IL8 (show IL8 Proteins), IL-1Ra (show IL1RN Proteins), MCP-1 (show CCL2 Proteins), and MIP-1beta are significantly lower in patients with type 1 diabetes than controls.

Mouse (Murine) Chemokine (C-C Motif) Ligand 4 (CCL4) interaction partners

  1. YY1 (show YY1 Proteins) regulates lung CCL4 transcription in pulmonary tuberculosis.

  2. Ccl4 mRNAs increased within 5 h after injury in mouse cortical slices.

  3. The chemokines monocyte chemotactic protein 1 (MCP1 (show CCL2 Proteins)), MIP1alpha, MIP1beta, interferon gamma (show IFNG Proteins)-induced protein 10 (IP-10 (show CXCL10 Proteins)), and eotaxin were induced in Saa1 (show SAA1 Proteins) TG mice.

  4. Aged mice had similar levels of IL-1beta (show IL1B Proteins), TNF (show TNF Proteins), IFN-gamma (show IFNG Proteins), IL-17 (show IL17A Proteins), and granulocyte colony-stimulating factor (show CSF3 Proteins) following S. pneumoniae infection, compared with young mice, but increased levels of the chemokines CXCL9 (show CXCL9 Proteins), CXCL12 (show CXCL12 Proteins), CCL3 (show CCL3 Proteins), CCL4, CCL5 (show CCL5 Proteins), CCL11, and CCL17 (show CCL17 Proteins).

  5. CCL4 and CCL5 expression was higher in livers of infected WSX-1(-/-) mice than infected WT mice, and hepatic CD4 T cells from WSX-1(-/-) mice expressed higher levels of CCR5 than cells from WT mice

  6. CCL4 upregulation was associated with increased Snail (show SNAI1 Proteins) expression and downregulation of p53 (show TP53 Proteins)/PTEN in high-grade PIN (show DYNLL1 Proteins) and prostate cancer

  7. Data indicate that Bifidobacterium infantis feeding to Salmonella-infected mice significantly reduced Peyer's patch MIP-1alpha (show CCL3 Proteins) and MIP-1beta secretion.

  8. IFN-gamma (show IFNG Proteins) and NOS2 (show NOS2 Proteins) repress CCL3 (show CCL3 Proteins) and CCL4 in vivo upon S. typhimurium infection of mice also repress CCL3 (show CCL3 Proteins) and CCL4 during S. typhimurium infection in bone marrow-derived macrophages.

  9. These results suggest that MIP-1beta is a novel key mediator, and the peripheral MIP-1beta-CCR5 axis contributes to neuropathic pain.

  10. results indicate that MIP-1beta is involved in the recruitment of bone marrow-derived monocyte lineage cells

Pig (Porcine) Chemokine (C-C Motif) Ligand 4 (CCL4) interaction partners

  1. In swine, IL-8 (show IL8 Proteins), TNF-ALPHA (show TNF Proteins), INOS (show NOS2 Proteins) AND MIP-1BETA were increased during mechanical ventilation in a time-related fashion.

Rhesus Monkey Chemokine (C-C Motif) Ligand 4 (CCL4) interaction partners

  1. CCL3 (show CCL3 Proteins), CCL4 and CCL5 (show CCL5 Proteins) gene expression was evaluated in response to simian-human immunodeficiency virus (SHIV) infection in a rhesus macaque model.

CCL4 Protein Profile

Protein Summary

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is similar to CCL4 which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals\; most individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The human genome reference assembly contains two copies of this gene. This record represents the more centromeric gene.

Gene names and symbols associated with CCL4

  • chemokine (C-C motif) ligand 4 (CCL4)
  • chemokine (C-C motif) ligand 4 (Ccl4)
  • chemokine (C-C motif) ligand 4-like 1 (CCL4L1)
  • Act-2 protein
  • ACT2 protein
  • AT744.1 protein
  • AT744.2 protein
  • CCL4 protein
  • CCL4L protein
  • CCL4L2 protein
  • G-26 protein
  • HC21 protein
  • K203 protein
  • LAG-1 protein
  • LAG1 protein
  • MIP-1-beta protein
  • MIP-1B protein
  • MIP-1BETA protein
  • Mip1-b protein
  • MIP1b protein
  • MIP1B1 protein
  • SCY4A protein
  • SCYA2 protein
  • SCYA4 protein
  • SCYA4L protein

Protein level used designations for CCL4

chemokine C-C motif ligand 4 , chemokine K203 , chemokine (C-C motif) ligand 4 , chemokine (C-C motif) ligand 4-like 2 , C-C motif chemokine 4 , MIP-1-beta , macrophage inflammatory protein 1-beta , macrophage inflammatory protein-1 beta , small inducible cytokine A4 , small-inducible cytokine A4 , G-26 T-lymphocyte-secreted protein , MIP-1-beta(1-69) , PAT 744 , SIS-gamma , T-cell activation protein 2 , lymphocyte activation gene 1 protein , secreted protein G-26 , small inducible cytokine A4 (homologous to mouse Mip-1b) , ACT2 , MIP-1 beta , immune activation protein 2 , C-C motif chemokine 4 homolog , chemokine-like ligand 1 , macrophage inflammatory protein 1-beta homolog , small-inducible cytokine A4 homolog , ACT-2 , immune activation gene 2 , putative MIP1-beta protein , CC chemokine ligand 4 , C-C motif chemokine 4-like , macrophage inflammatory protein-1b2 , monocyte adherence-induced protein 5-alpha , chemokine CCL4/MIP-1BETA , macrophage inflammatory protein 1 beta

GENE ID SPECIES
395468 Gallus gallus
454593 Pan troglodytes
455004 Pan troglodytes
116637 Rattus norvegicus
6351 Homo sapiens
20303 Mus musculus
395551 Gallus gallus
396668 Sus scrofa
100008984 Oryctolagus cuniculus
414347 Bos taurus
448786 Canis lupus familiaris
9560 Homo sapiens
574217 Macaca mulatta
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