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anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) Antibodies

CXCL1 encodes a member of the CXC subfamily of chemokines.

list all antibodies Gene Name GeneID UniProt
Anti-Rat CXCL1 CXCL1 81503 P14095
Anti-Mouse CXCL1 CXCL1 14825 P12850
Anti-Human CXCL1 CXCL1 2919 P09341
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More Antibodies against Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) Interaction Partners

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) interaction partners

  1. Nlrp12 (show NLRP12 Antibodies) deficiency caused increased neutrophil migration towards the chemokine (show CCL1 Antibodies) CXCL1 and the neutrophil parasite Leishmania major, revealing NLRP12 (show NLRP12 Antibodies) as a negative regulator of directed neutrophil migration under these conditions.

  2. CXCL1 monomer-dimer distribution and receptor interactions are highly coupled and regulate neutrophil trafficking and that injury in the context of disease is a consequence of inappropriate CXCR2 (show CXCR2 Antibodies) activation

  3. Chemotactic activity of stellate cell-derived CXCL1 was assayed in vitro on neutrophils upon TLR4 (show TLR4 Antibodies) activation.

  4. IL-17RA (show IL17RA Antibodies) regulates CXL-1 and 5 production in the lungs during the adaptive response.

  5. Data suggest that CXCL1/IL-8 (show IL8 Antibodies), released from osteoclasts in an autoantibody-dependent manner, produces pain by activating sensory neurons.

  6. p53 (show TP53 Antibodies)-mediated induction of PAI-1 (show SERPINE1 Antibodies) expression due to chronic CS exposure exacerbates lung inflammation through elaboration of CXCL1, CXCL2 (show CXCL2 Antibodies), and CXCR2 (show CXCR2 Antibodies).

  7. TGF-beta (show TGFB1 Antibodies) negatively regulates CXCL1 expression in CAFs (show TBX1 Antibodies) through Smad2 (show SMAD2 Antibodies)/3 binding to the promoter, and through suppression of HGF/c-Met autocrine signaling

  8. work shows parallel networks of necroptosis-induced CXCL1 and Mincle (show CLEC4E Antibodies) signalling that promote macrophage-induced adaptive immune suppression and thereby enable pancreatic ductal adenocarcinoma progression

  9. Repeated social defeat-induced VCAM-1 (show VCAM1 Antibodies) protein expression were localized to the vasculature of brain regions implicated in fear and anxiety responses.

  10. In a chronic-binge ethanol-feeding model, the hepatic TLR2 and TLR9-dependent MyD88-dependent pathway mediates CXCL1 production, resulting in the development of alcohol-mediated liver injury.

Human Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) interaction partners

  1. these findings suggest that CXCL1 plays critical roles in the growth and apoptosis of hepatocellular carcinoma

  2. BBP (show TP53BP2 Antibodies) also stimulated the production of CXCL1/GROalpha by TADCs, which increased the angiogenesis of breast cancer in a mouse model

  3. Intense glomerular CXCL1 expression was observed in biopsy specimens from patients with lupus nephritis

  4. hCXCL1-GAG interactions provide stringent control over regulating chemokine (show CCL1 Antibodies) levels and receptor accessibility and activation, and that chemotactic gradients mediate cellular trafficking to the target site.

  5. Urine CXCL1 is a promising, non-invasive molecular marker for tumor detection and outcome prediction in patients with bladder cancer .

  6. CXCR2 (show CXCR2 Antibodies)-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma

  7. Polymorphisms in the promoter regions of the CXCL1 and CXCL2 (show CXCL2 Antibodies) genes contribute to increased risk of alopecia areata in the Korean population

  8. VEGF (show VEGFA Antibodies) markedly induces CXCL1 release in A549 lung epithelial cells.

  9. TGF-beta (show TGFB1 Antibodies) negatively regulates CXCL1 expression in CAFs (show TBX1 Antibodies) through Smad2 (show SMAD2 Antibodies)/3 binding to the promoter, and through suppression of HGF/c-Met autocrine signaling

  10. work shows parallel networks of necroptosis-induced CXCL1 and Mincle (show CLEC4E Antibodies) signalling that promote macrophage-induced adaptive immune suppression and thereby enable pancreatic ductal adenocarcinoma progression

Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) Antigen Profile

Protein Summary

This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Gene names and symbols associated with CXCL1

  • chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1) antibody
  • chemokine (C-X-C motif) ligand 2 (CXCL2) antibody
  • chemokine (C-X-C motif) ligand 1 (Cxcl1) antibody
  • chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (GRO1) antibody
  • CINC-1 antibody
  • CXCL1 antibody
  • FSP antibody
  • Gro antibody
  • GRO1 antibody
  • GROa antibody
  • KC antibody
  • Mgsa antibody
  • MGSA-a antibody
  • N51 antibody
  • NAP-3 antibody
  • SCYB1 antibody

Protein level used designations for CXCL1

chemokine CXCL1/GRO-ALPHA , growth-regulated alpha protein , chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) , melanoma growth stimulatory activity homolog , C-X-C motif chemokine 1 , cytokine-induced neutrophil chemoattractant 1 , gro , platelet-derived growth factor-inducible protein KC , GRO1 oncogene , KC/GR)-alpha , KC/GRO-alpha , alpha-chemokine , secretory protein N51 , growth regulated protein GRO , growth regulated , GRO-alpha(1-73) , GRO1 oncogene (melanoma growth stimulating activity, alpha) , GRO1 oncogene (melanoma growth-stimulating activity) , MGSA alpha , fibroblast secretory protein , melanoma growth stimulatory activity alpha , neutrophil-activating protein 3 , GRO-alpha , growth related gene 1 , growth-regulated protein homolog alpha

GENE ID SPECIES
574222 Macaca mulatta
702067 Macaca mulatta
740567 Pan troglodytes
100034121 Equus caballus
81503 Rattus norvegicus
14825 Mus musculus
100135510 Cavia porcellus
100689059 Cricetulus griseus
2919 Homo sapiens
281212 Bos taurus
443380 Ovis aries
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