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The protein encoded by CXCR1 is a member of the G-protein-coupled receptor family. Additionally we are shipping CXCR1 Kits (39) and CXCR1 Proteins (5) and many more products for this protein.
Showing 10 out of 161 products:
Human Monoclonal CXCR1 Primary Antibody for FACS, IHC - ABIN4899069
Kline, Donovan, Wellik, Lust, Jin, Moon-Tasson, Xiong, Witzig, Kumar, Rajkumar, Lust: Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression. in Leukemia research 2007
Show all 23 references for ABIN4899069
Human Monoclonal CXCR1 Primary Antibody for FACS - ABIN4895413
Maru, Holloway, Flynn, Lancashire, Loughlin, Male, Romero: Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation. in Journal of neuroimmunology 2008
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Human Polyclonal CXCR1 Primary Antibody for EIA, IHC (fro) - ABIN492882
Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003
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Human Polyclonal CXCR1 Primary Antibody for EIA, IHC (fro) - ABIN492884
Caulfield, Fernandez, Snetkov, Lee, Hawrylowicz: CXCR4 expression on monocytes is up-regulated by dexamethasone and is modulated by autologous CD3+ T cells. in Immunology 2002
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Mouse (Murine) Polyclonal CXCR1 Primary Antibody for EIA, IHC (fro) - ABIN492886
Segerer: The role of chemokines and chemokine receptors in progressive renal diseases. in American journal of kidney diseases : the official journal of the National Kidney Foundation 2003
Show all 3 references for ABIN492886
Human Polyclonal CXCR1 Primary Antibody for IF (p), IHC (p) - ABIN730873
Tian, Lv, Yang, Zhang, Yu, Zhu, Xiao, Zhu: Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats. in International journal of clinical and experimental pathology 2014
Show all 3 references for ABIN730873
Human Monoclonal CXCR1 Primary Antibody for FACS - ABIN4895409
Maxwell, Gallagher, Seaton, Wilson, Scullin, Pettigrew, Stratford, Williams, Johnston, Waugh: HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. in Oncogene 2007
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Human Monoclonal CXCR1 Primary Antibody for FACS - ABIN4895405
Ghirelli, Zollinger, Soumelis: Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells. in Blood 2010
Human Polyclonal CXCR1 Primary Antibody for IHC (fro), IHC (p) - ABIN152848
Krohn, Kapoor, Enami, Follenzi, Bandi, Joseph, Gupta: Hepatocyte transplantation-induced liver inflammation is driven by cytokines-chemokines associated with neutrophils and Kupffer cells. in Gastroenterology 2009
The results demonstrate that CXCR1 polymorphism can influence somatic cell count and milk neutrophil viability following experimental mastitis.
(PCR) was used to detect the methylation status of CXCR1 CpG island, and quantitative fluorescence PCR was used to detect CXCR1 expression in bovine mammary tissue
Polymorphisms in CXCR1 are significantly associated with bovine mastitis
In the present study no association could be detected between superoxide production by isolated bovine neutrophils during early lactation and CXCR1 gene polymorphism. IL-8 (show IL8 Antibodies) showed to possess inhibitory effects on ROS (show ROS1 Antibodies) generation in bovine neutrophils.
CXCR1 polymorphisms influence viability and concentration of milk polymorphonuclear neutrophilic leukocytes.
The results suggests the possible role of CXCR1 gene SNPs in the host response against mastitis.
The situation of CXCR1 polymorphisms in Chinese Holstein cattle and determine the relationship between the CXCR1 SNPs and mastitis resistance.
Association between interleukin-8 receptor-alpha (CXCR1) polymorphism and disease incidence, production, reproduction, and survival in Holstein cows.
The aim of this study was to demonstrate the presence of the two SNPs in the CXCR1 gene of Japanese Black cattle and examine the association between the SNPs and clinical diseases including intestinal and respiratory diseases in calves.
Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.
this study shows that downregulation of CD182 (show CXCR3 Antibodies) after stimulation with IL-8 (show IL8 Antibodies) is more pronounced in adults than in neonates, whereas fMLP (show FPR1 Antibodies) induces changes in receptor expression that are of the same magnitude in neutrophils from neonates as from adults
findings present that miR (show MLXIP Antibodies)-940 acts as a pivotal adaptor of CXCR2 (show CXCR2 Antibodies) and its transcription downregulated CXCR2 (show CXCR2 Antibodies) expression to decrease HCC (show FAM126A Antibodies) invasion and migration in vitro.
Our findings suggest that CXCL3 (show CXCL3 Antibodies) and its receptor CXCR2 (show CXCR2 Antibodies) are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.
Data suggest that neutrophil-activating peptide 2 (NAP-2 (show PPBP Antibodies)) secreted by NK cells can bind to CXC Chemokine Receptor (show CXCR4 Antibodies) 2 (CXCR2 (show CXCR2 Antibodies)) on mesenchymal stem cells (MSCs) leading to stimulation of its recruitment.
Study shows that CXCR1 promoted gastric cancer cell proliferation, migration and invasion.
High CXCR2 (show CXCR2 Antibodies) expression is associated with pancreatic cancer.
These data provide rationale that targeting CXCR1/2 with small molecule inhibitors may enhance chemotherapeutic efficacy for the treatment of gastric cancer.
Letter: cold temperatures up regulate CXCR2 (show CXCR2 Antibodies) ligand Il8 (show IL8 Antibodies) in microvascular endothelial cells which may contribute to neutrophil recruitment and inflammation in skin from patients with livedo vasculopathy with winter ulcerations.
The results showed that the expression of N-Ac-PGP receptors (CXCR1 and CXCR2) in CESCs was upregulated by N-Ac-PGP.
The results of this study show that the CXCR2 (show CXCR2 Antibodies) rs1126579 polymorphism is significantly associated with ischemic stroke, both individually and in combination with the genotype and/or alleles of other chemokine (show CCL1 Antibodies) genes.
These data demonstrate a biological function for mouse Cxcr1 in vivo and indicate that CXCR1-dependent neutrophil effector function is a critical innate protective mechanism of fungal clearance and host survival in systemic candidiasis.
in view of recently-published experimental data obtained in NOD mice, we argue for possible Cxcr1 involvement in type 1 diabetes pathogenesi
CXCR1 expression is induced in staphylococcus aureus-infected macrophages but not in control macrophages.
Pharmacologic blockade of CXCR1/2 as well as genetic deletion of NAP-2 (show PPBP Antibodies) markedly reduced leukocyte shape change and intrathrombus migration.
Blockade of the CXCL1 (show CXCL1 Antibodies)-CXCR1/2 axis in mice improved intrahepatic islet engraftment. The CXCR1/2-mediated pathway is a regulator of islet damage.
Upon activation by CXCL8 (show IL8 Antibodies), CXCR1 predominantly couples to G protein-coupled receptor (show GPR34 Antibodies) kinase (GRK)2 (show ADRBK1 Antibodies) to modulate leukocyte functions.
Xiaotan Sanjie Decoction XTSJD can decrease the protein expressions of IL-8 (show IL8 Antibodies) and its receptors CXCR1/CXCR2 (show CXCR2 Antibodies) in tumor xenografts and gastric tissue adjacent to the tumor.
data suggest that CXCR1 does not mediate the proliferative effects of ELR+ CXC chemokines during liver regeneration after partial hepatectomy
CXCR1 expression is induced in hepatocytes after injury. Furthermore, the data suggest that CXCR1 has divergent effects from CXCR2 (show CXCR2 Antibodies) and appears to facilitate repair and regenerative responses after I/R injury.
CX3CL1 (show CX3CL1 Antibodies)-CX3CR1 (show CX3CR1 Antibodies) axis can regulate the expression of iNOS (show NOS2 Antibodies), a crucial mediator of DSS (show PMP22 Antibodies)-induced colitis.
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.
C-X-C chemokine receptor type 2
, IL-8R B
, high affinity interleukin-8 receptor B
, interleukin 8 receptor, alpha
, chemokine (C-X-C motif) receptor 1
, C-X-C chemokine receptor type 1
, IL-8 receptor type 1
, IL-8R A
, high affinity interleukin-8 receptor A
, interleukin-8 receptor type 1
, interleukin-8 receptor type A
, CXC chemokine receptor 1
, chemokine (C-X-C motif) receptor 2
, interleukin 8 receptor, beta
, chemokine (C-X-C) motif receptor 1
, chemokine (C-X-C) receptor 1
, interleukin 8 receptor alpha
, IL-8 receptor
, CXCR2 gene for IL8 receptor type B
, GRO/MGSA receptor
, IL-8 receptor type 2
, chemokine (CXC) receptor 2
, interleukin 8 receptor B
, interleukin 8 receptor type 2
, interleukin-8 receptor type B