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anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) Antibodies

The protein encoded by CXCR1 is a member of the G-protein-coupled receptor family. Additionally we are shipping CXCR1 Kits (43) and CXCR1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXCR1 3577 P25024
CXCR1 227288 Q810W6
CXCR1 54258 P70612
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Top anti-CXCR1 Antibodies at antibodies-online.com

Showing 10 out of 97 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat colitis tissue labeled with Anti-CXCR1/IL-8RA Polyclonal Antibody, Unconjugated (ABIN730873) at 1:200, followed by conjugation to the secondary antibody and DAB staining Lane 1: rat kidney lysates Lane 2: rat brain lysates probed with Anti CXCR1/IL-8RA Polyclonal Antibody, Unconjugated (ABIN730873) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 40kD. Observed band size: 40kD. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IP, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IP, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Mouse Goat Un-conjugated EIA, IHC (fro), IP, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC (p) Staining of eccrine sweat glands in human skin using ABIN121970 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CXCR1 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-CXCR1 antibody IHC staining of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048471 dilution 16 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IHC (p) Anti-CXCR1 antibody  ABIN1048469 IHC staining of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of CXCR1 in Jurkat cell lysate: 1. Anti-CXCR1 (extracellular) antibody, (1:200). 2. Anti- CXCR1 (extracellular) antibody, preincubated with the control peptide antigen. Indirect Flow cytometry analysis of Jurkat living cells: Black: Unstained cells. Green: Cells + Anti-CXCR1 (extracellular) antibody, (10 µg/5x105 cells). 50 μL Log in to see 10 to 11 Days
$678.57
Details
Human Mouse FITC FACS 100 Tests Log in to see 10 to 12 Days
$211.97
Details

CXCR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CXCR1 Antibodies

  1. Human Monoclonal CXCR1 Primary Antibody for FACS - ABIN2661541 : Emadi, Clay, Desterke, Guerton, Maquarre, Charpentier, Jasmin, Le Bousse-Kerdilès: IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis. in Blood 2005 (PubMed)
    Show all 5 references for ABIN2661541

  2. Human Polyclonal CXCR1 Primary Antibody for EIA, IHC (fro) - ABIN492884 : Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003 (PubMed)
    Show all 3 references for ABIN492884

  3. Mouse (Murine) Polyclonal CXCR1 Primary Antibody for EIA, IHC (fro) - ABIN492886 : Caulfield, Fernandez, Snetkov, Lee, Hawrylowicz: CXCR4 expression on monocytes is up-regulated by dexamethasone and is modulated by autologous CD3+ T cells. in Immunology 2002 (PubMed)
    Show all 3 references for ABIN492886

  4. Human Polyclonal CXCR1 Primary Antibody for EIA, IHC (fro) - ABIN492882 : Segerer: The role of chemokines and chemokine receptors in progressive renal diseases. in American journal of kidney diseases : the official journal of the National Kidney Foundation 2003 (PubMed)
    Show all 3 references for ABIN492882

  5. Human Polyclonal CXCR1 Primary Antibody for IF (p), IHC (p) - ABIN730873 : Tian, Lv, Yang, Zhang, Yu, Zhu, Xiao, Zhu: Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats. in International journal of clinical and experimental pathology 2014 (PubMed)
    Show all 2 references for ABIN730873

More Antibodies against CXCR1 Interaction Partners

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 1 (CXCR1) interaction partners

  1. (PCR) was used to detect the methylation status of CXCR1 CpG island, and quantitative fluorescence PCR was used to detect CXCR1 expression in bovine mammary tissue

  2. Polymorphisms in CXCR1 are significantly associated with bovine mastitis

  3. In the present study no association could be detected between superoxide production by isolated bovine neutrophils during early lactation and CXCR1 gene polymorphism. IL-8 (show IL8 Antibodies) showed to possess inhibitory effects on ROS (show ROS1 Antibodies) generation in bovine neutrophils.

  4. CXCR1 polymorphisms influence viability and concentration of milk polymorphonuclear neutrophilic leukocytes.

  5. The results suggests the possible role of CXCR1 gene SNPs in the host response against mastitis.

  6. The situation of CXCR1 polymorphisms in Chinese Holstein cattle and determine the relationship between the CXCR1 SNPs and mastitis resistance.

  7. Association between interleukin-8 receptor-alpha (CXCR1) polymorphism and disease incidence, production, reproduction, and survival in Holstein cows.

  8. The aim of this study was to demonstrate the presence of the two SNPs in the CXCR1 gene of Japanese Black cattle and examine the association between the SNPs and clinical diseases including intestinal and respiratory diseases in calves.

  9. Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.

  10. no statistically significant association of the SNP CXCR1+777 or CXCR1-1768 with SCS (show TWIST1 Antibodies) was found

Human Chemokine (C-X-C Motif) Receptor 1 (CXCR1) interaction partners

  1. The results of this study show that the CXCR2 (show CXCR2 Antibodies) rs1126579 polymorphism is significantly associated with ischemic stroke, both individually and in combination with the genotype and/or alleles of other chemokine (show CCL1 Antibodies) genes.

  2. These data demonstrate a biological function for mouse Cxcr1 in vivo and indicate that CXCR1-dependent neutrophil effector function is a critical innate protective mechanism of fungal clearance and host survival in systemic candidiasis.

  3. Report increased expression of CXCR1 in active pulmonary tuberculosis patients and decreased leukocyte oxidative capacity.

  4. Evaluation of GPER1, EGFR (show EGFR Antibodies) and CXCR1 mRNA/protein expression may be helpful in differential diagnosis of malignant follicular thyroid carcinoma and benign follicular thyroid adenoma.

  5. These studies provide direct evidence linking the activation of IL8 (show IL8 Antibodies), DNA demethylation and the induction of the OA process with important therapeutic implications therein for patients with this debilitating disease.

  6. Studied the expression of CXCL8 (show IL8 Antibodies)-CXCR1/2 pathway, its impact on cell proliferation and cytokine expression in human colorectal carcinoma HCT116 cells.

  7. Inhibition of IL-8 (show IL8 Antibodies) signalling can enhance response in platinum sensitive and resistant high grade serous ovarian carcinoma.

  8. CXCR2 (show CXCR2 Antibodies) expression is enriched in human atherosclerotic coronary artery.

  9. CXCR2 (show CXCR2 Antibodies)-CXCL1 (show CXCL1 Antibodies) axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma

  10. we found the mRNA level of NF-kappaB (show NFKB1 Antibodies) and IL-8 (show IL8 Antibodies) was higher in gastric ulcer patients, especially in patients with H.pylori-positive gastric ulcer.

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 1 (CXCR1) interaction partners

  1. These data demonstrate a biological function for mouse Cxcr1 in vivo and indicate that CXCR1-dependent neutrophil effector function is a critical innate protective mechanism of fungal clearance and host survival in systemic candidiasis.

  2. in view of recently-published experimental data obtained in NOD mice, we argue for possible Cxcr1 involvement in type 1 diabetes pathogenesi

  3. CXCR1 expression is induced in staphylococcus aureus-infected macrophages but not in control macrophages.

  4. Pharmacologic blockade of CXCR1/2 as well as genetic deletion of NAP-2 (show PPBP Antibodies) markedly reduced leukocyte shape change and intrathrombus migration.

  5. Blockade of the CXCL1 (show CXCL1 Antibodies)-CXCR1/2 axis in mice improved intrahepatic islet engraftment. The CXCR1/2-mediated pathway is a regulator of islet damage.

  6. Upon activation by CXCL8 (show IL8 Antibodies), CXCR1 predominantly couples to G protein-coupled receptor (show GPR34 Antibodies) kinase (GRK)2 (show ADRBK1 Antibodies) to modulate leukocyte functions.

  7. Xiaotan Sanjie Decoction XTSJD can decrease the protein expressions of IL-8 (show IL8 Antibodies) and its receptors CXCR1/CXCR2 (show CXCR2 Antibodies) in tumor xenografts and gastric tissue adjacent to the tumor.

  8. data suggest that CXCR1 does not mediate the proliferative effects of ELR+ CXC chemokines during liver regeneration after partial hepatectomy

  9. CXCR1 expression is induced in hepatocytes after injury. Furthermore, the data suggest that CXCR1 has divergent effects from CXCR2 (show CXCR2 Antibodies) and appears to facilitate repair and regenerative responses after I/R injury.

  10. CX3CL1 (show CX3CL1 Antibodies)-CX3CR1 (show CX3CR1 Antibodies) axis can regulate the expression of iNOS (show NOS2 Antibodies), a crucial mediator of DSS (show PMP22 Antibodies)-induced colitis.

CXCR1 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with CXCR1

  • interleukin 8 receptor, beta (CXCR2) antibody
  • interleukin 8 receptor, alpha (IL8RA) antibody
  • chemokine (C-X-C motif) receptor 1 (CXCR1) antibody
  • chemokine (C-X-C motif) receptor 1 (Cxcr1) antibody
  • chemokine (C-X-C motif) receptor 2 (CXCR2) antibody
  • C-C antibody
  • C-C-CKR-1 antibody
  • CD128 antibody
  • CD181 antibody
  • CD182 antibody
  • CDw128a antibody
  • CDw128b antibody
  • CKR-1 antibody
  • CMKAR1 antibody
  • CMKAR2 antibody
  • CXCR-1 antibody
  • CXCR1 antibody
  • CXCR2 antibody
  • IL-8RA antibody
  • IL8R1 antibody
  • IL8R2 antibody
  • Il8ra antibody
  • IL8RB antibody
  • IL8RBA antibody

Protein level used designations for CXCR1

C-X-C chemokine receptor type 2 , CXC-R2 , CXCR-2 , IL-8R B , high affinity interleukin-8 receptor B , interleukin 8 receptor, alpha , chemokine (C-X-C motif) receptor 1 , C-X-C chemokine receptor type 1 , CXC-R1 , CXCR-1 , IL-8 receptor type 1 , IL-8R A , high affinity interleukin-8 receptor A , interleukin-8 receptor type 1 , interleukin-8 receptor type A , CXC chemokine receptor 1 , chemokine (C-X-C motif) receptor 2 , interleukin 8 receptor, beta , chemokine (C-X-C) motif receptor 1 , chemokine (C-X-C) receptor 1 , interleukin 8 receptor alpha , IL-8 receptor , CXCR2 gene for IL8 receptor type B , GRO/MGSA receptor , IL-8 receptor type 2 , chemokine (CXC) receptor 2 , interleukin 8 receptor B , interleukin 8 receptor type 2 , interleukin-8 receptor type B

GENE ID SPECIES
281863 Bos taurus
100127487 Sus scrofa
3577 Homo sapiens
227288 Mus musculus
478906 Canis lupus familiaris
100125580 Bos taurus
54258 Rattus norvegicus
100328622 Oryctolagus cuniculus
100461947 Pongo abelii
692074 Macaca mulatta
470645 Pan troglodytes
3579 Homo sapiens
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