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anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) Antibodies

CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Additionally we are shipping CXCR3 Kits (40) and CXCR3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXCR3 2833 P49682
CXCR3 84475 Q9JII9
CXCR3 12766 O88410
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Top anti-CXCR3 Antibodies at antibodies-online.com

Showing 10 out of 249 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB CXCR3 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CXCR3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CXCR3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562 cells, using CXCR3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat exfoliated cells labeled with Anti-CXCR3 Polyclonal Antibody, Unconjugated (ABIN678653) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Mouse Un-conjugated FACS 0.5 mg Log in to see 5 to 6 Days
$405.02
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CXCR3 Picoband antibody,  IHC(P): Human Lung Cancer Tissue Anti-CXCR3 Picoband antibody,  All lanes: Anti-CXCR3 at 0.5ug/ml Lane 1: Colo320 Whole Cell Lysate at 40ug Lane 2: SGC Whole Cell Lysate at 40ug Predicted bind size: 41KD Observed bind size: 41KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB CXCR3 Antibody (Center)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CXCR3 antibody detected the CXCR3 protein (arrow). CXCR3 Antibody (Center)  immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the CXCR3 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Pacific Blue FACS, ICFC 100 μg Log in to see 10 to 12 Days
$364.16
Details
Mouse Hamster Biotin FACS 50 μg Log in to see 10 to 12 Days
$135.88
Details

CXCR3 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CXCR3 Antibodies

  1. Mouse (Murine) Monoclonal CXCR3 Primary Antibody for FACS - ABIN2660967 : Krug, Uppaluri, Facchetti, Dorner, Sheehan, Schreiber, Cella, Colonna: IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 7 references for ABIN2660967

  2. Human Monoclonal CXCR3 Primary Antibody for FACS, ICFC - ABIN2662210 : Aksoy, Yang, Ji, Reddy, Shahabuddin, Litvin, Rogers, Kelsen: CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation. in American journal of physiology. Lung cellular and molecular physiology 2006 (PubMed)
    Show all 6 references for ABIN2662210

  3. Mouse (Murine) Polyclonal CXCR3 Primary Antibody for IF (p), IHC (p) - ABIN678653 : Zhang, Fei, Gao, Liu, Zhang: The role of CXCR3 in the induction of primary biliary cirrhosis. in Clinical & developmental immunology 2011 (PubMed)
    Show all 4 references for ABIN678653

  4. Human Polyclonal CXCR3 Primary Antibody for EIA, FACS - ABIN951214 : Zhou, Tang, Qin, Gayed, Li, Skokos, Kyriakides, Pober, Tellides: CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. in The Journal of experimental medicine 2010 (PubMed)
    Show all 4 references for ABIN951214

  5. Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN1176889 : Loetscher, Gerber, Loetscher, Jones, Piali, Clark-Lewis, Baggiolini, Moser: Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. in The Journal of experimental medicine 1997 (PubMed)
    Show all 3 references for ABIN1176889

  6. Human Polyclonal CXCR3 Primary Antibody for IHC, ELISA - ABIN1582555 : Milićević, Miljković, Milićević, Labudović-Borović, Wang, Laan, Peterson, Randall, Westermann: Role of CCL19/21 and its possible signaling through CXCR3 in development of metallophilic macrophages in the mouse thymus. in Histochemistry and cell biology 2011 (PubMed)
    Show all 2 references for ABIN1582555

  7. Human Polyclonal CXCR3 Primary Antibody for ELISA, WB - ABIN334381 : Martini, Zulian, Calabrese, Bortoli, Facco, Cabrelle, Valente, Zacchello, Agostini: CXCR3/CXCL10 expression in the synovium of children with juvenile idiopathic arthritis. in Arthritis research & therapy 2005 (PubMed)

  8. Human Polyclonal CXCR3 Primary Antibody for ELISA, WB - ABIN1535574 : Marchese, Heiber, Nguyen, Heng, Saldivia, Cheng, Murphy, Tsui, Shi, Gregor: Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors. in Genomics 1996 (PubMed)

More Antibodies against CXCR3 Interaction Partners

Human Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. CXCL10 (show CXCL10 Antibodies)/CXCR3 axis promotes gastric cancer cell invasion and migration by upregulating MMP-2 (show MMP2 Antibodies) and MMP-9 (show MMP9 Antibodies) production via PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) pathway.

  2. CXCR3 expression in chronic lymphocytic leukemia cells was a strong determinant of a worse clinical outcome.

  3. Speculate that aberrant expression of CXCR3 in marginal zone lymphoma of the skin is associated with migration of lymphoma cells to the epidermis and could lead to an epidermotropic pattern.

  4. CXCR3 role in autoimmune thyroiditis [review]

  5. Both CXCL10 (show CXCL10 Antibodies) and CXCR3 appeared to be useful in differentiating T1R reaction in borderline leprosy while CXCR3 alone differentiated BT from BT-T1R

  6. CXCR3 expression was upregulated in advanced gastric cancer and was associated with increased CD4 (show CD4 Antibodies)+, CD8 (show CD8A Antibodies)+ tumor-infiltrating lymphocyte infiltration and improved overall survival

  7. CXCR3 was also linked to steatosis through inducing hepatic lipogenic genes

  8. congruent with the concept that inflammation plays a key role in the pathogenesis of LV dysfunction, MIG (show CXCL9 Antibodies), IP10 (show CXCL10 Antibodies) and I-TAC (show CXCL11 Antibodies) add diagnostic accuracy over and beyond NT-pro BNP (show BNC2 Antibodies).

  9. Suggest that aberrant CXCR3 expression may play crucial roles in suppressing prostate carcinoma metastasis by inhibiting cell proliferation and invasion through the PCLbeta signaling pathway.

  10. The expression of the chemokine (show CCL1 Antibodies) receptors CXCR3, CXCR4 (show CXCR4 Antibodies) and CXCR7 (show CXCR7 Antibodies) and their ligands.

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. Circulating levels of chemokines that activate CXCR3 are elevated in non-obese diabetic (NOD) mice, consistent with clinical findings in human diabetes.

  2. CXCR3 interacts with IL-10 (show IL10 Antibodies) secreted by CD8 (show CD8A Antibodies)+CD122 (show IL2RB Antibodies)+ regulatory T cells in a mouse model of Acute Lung Injury and promotes interferon-gamma (show IFNG Antibodies) and CXCL10 (show CXCL10 Antibodies) release.

  3. This study demonstrates a previously unrecognized role of CXCR3 signaling in glial cells in negatively regulating Th17 cell expansion during experimental autoimmune encephalomyelitis

  4. CXCR3 was also linked to steatosis through inducing hepatic lipogenic genes

  5. findings demonstrate that targeting CXCR3 is effective in both tumor and host compartments, and suggest that CXCR3 inhibition is likely to avoid adverse effects on host cells

  6. Activation of the CXCL10 (show CXCL10 Antibodies)/CXCR3 pathway has an important role in retinal inflammation and neuronal injury after high intraocular pressure-induced ischemia.

  7. STAT3 (show STAT3 Antibodies) in CD8 (show CD8A Antibodies)+ T Cells Inhibits Their Tumor Accumulation by Downregulating CXCR3/CXCL10 (show CXCL10 Antibodies) Axis

  8. CXCR3-mediated trafficking of regulatory T cells could represent a mechanism of homeostatic immunoregulation during diabetogeneesis.

  9. These studies identify CXCR3-mediated trafficking at the tumour vascular interface as a critical checkpoint to effective T-cell-based cancer immunotherapy.

  10. activated T cells display a subtle distance-dependent chemotaxis toward clusters of infected cells and this is mediated by CXCR3 and its ligands.

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CXCR3 expression

CXCR3 Antigen Profile

Protein Summary

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

Gene names and symbols associated with CXCR3

  • chemokine (C-X-C motif) receptor 3 (CXCR3) antibody
  • chemokine (C-X-C motif) receptor 3 (cxcr3) antibody
  • chemokine (C-X-C motif) receptor 3 (Cxcr3) antibody
  • CD182 antibody
  • Cd183 antibody
  • CKR-L2 antibody
  • Cmkar3 antibody
  • CXC-R3 antibody
  • CXCR-3 antibody
  • cxcr3 antibody
  • Gpr9 antibody
  • IP10-R antibody
  • Mig-R antibody
  • MigR antibody

Protein level used designations for CXCR3

chemokine (C-X-C motif) receptor 3 , C-X-C chemokine receptor type 3 , CXC-R3 , CXCR-3 , G protein-coupled receptor 9 , IP-10 receptor , IP10 receptor , Mig receptor , chemokine (C-X-C) receptor 3 , interferon-inducible protein 10 receptor , CXC chemokine receptor 3 , Interferon-inducible protein 10 receptor

GENE ID SPECIES
465704 Pan troglodytes
496477 Xenopus (Silurana) tropicalis
699438 Macaca mulatta
2833 Homo sapiens
84475 Rattus norvegicus
12766 Mus musculus
497018 Bos taurus
491952 Canis lupus familiaris
100860874 Capra hircus
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