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CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Additionally we are shipping CXCR3 Kits (48) and CXCR3 Proteins (7) and many more products for this protein.
Showing 10 out of 174 products:
Human Monoclonal CXCR3 Primary Antibody for FACS, ICFC - ABIN2662210
Aksoy, Yang, Ji, Reddy, Shahabuddin, Litvin, Rogers, Kelsen: CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation. in American journal of physiology. Lung cellular and molecular physiology 2006
Show all 6 references for ABIN2662210
Human Polyclonal CXCR3 Primary Antibody for EIA, FACS - ABIN951214
Zhou, Tang, Qin, Gayed, Li, Skokos, Kyriakides, Pober, Tellides: CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. in The Journal of experimental medicine 2010
Show all 4 references for ABIN951214
Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN1176889
Loetscher, Gerber, Loetscher, Jones, Piali, Clark-Lewis, Baggiolini, Moser: Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. in The Journal of experimental medicine 1997
Show all 3 references for ABIN1176889
Mouse (Murine) Polyclonal CXCR3 Primary Antibody for IF (p), IHC (p) - ABIN678653
Zhang, Fei, Gao, Liu, Zhang: The role of CXCR3 in the induction of primary biliary cirrhosis. in Clinical & developmental immunology 2011
Show all 3 references for ABIN678653
Human Polyclonal CXCR3 Primary Antibody for IHC, ELISA - ABIN1582555
Milićević, Miljković, Milićević, Labudović-Borović, Wang, Laan, Peterson, Randall, Westermann: Role of CCL19/21 and its possible signaling through CXCR3 in development of metallophilic macrophages in the mouse thymus. in Histochemistry and cell biology 2011
Show all 2 references for ABIN1582555
Human Polyclonal CXCR3 Primary Antibody for ELISA, WB - ABIN334381
Martini, Zulian, Calabrese, Bortoli, Facco, Cabrelle, Valente, Zacchello, Agostini: CXCR3/CXCL10 expression in the synovium of children with juvenile idiopathic arthritis. in Arthritis research & therapy 2005
Human Polyclonal CXCR3 Primary Antibody for ELISA, WB - ABIN1535574
Marchese, Heiber, Nguyen, Heng, Saldivia, Cheng, Murphy, Tsui, Shi, Gregor: Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors. in Genomics 1996
congruent with the concept that inflammation plays a key role in the pathogenesis of LV dysfunction, MIG (show CXCL9 Antibodies), IP10 (show CXCL10 Antibodies) and I-TAC (show CXCL11 Antibodies) add diagnostic accuracy over and beyond NT-pro BNP (show BNC2 Antibodies).
Suggest that aberrant CXCR3 expression may play crucial roles in suppressing prostate carcinoma metastasis by inhibiting cell proliferation and invasion through the PCLbeta signaling pathway.
The expression of the chemokine (show CCL1 Antibodies) receptors CXCR3, CXCR4 (show CXCR4 Antibodies) and CXCR7 (show CXCR7 Antibodies) and their ligands.
This study is aimed at the optimization of a new analytical method for metabolic profiling with parallel bioaffinity assessment of CXCR3 ligands of the azaquinazolinone and piperazinyl-piperidine class and their metabolites.
CXCR3-A, the predominant form in hematopoietic cells, mediates tumor "go" signaling by promoting cell proliferation, survival, chemotaxis, invasion and metastasis; while CXCR3-B, on epithelial cells, mediates "stop" signaling
Common variants of CXCR3 and its ligands CXCL10 (show CXCL10 Antibodies) and CXCL11 (show CXCL11 Antibodies) are associated with vascular permeability of dengue infection in peninsular Malaysia.
our study suggested a potential use of CXCR3 overexpression as a prognostic marker for gastric cancer
CD4 (show CD4 Antibodies)+ T cells demonstrated markedly decreased CXCR3 expression.
Results indicate that CXC chemokine (show CXCL12 Antibodies) receptors 3 (CXCR3) contributes to spontaneous preterm birth (SPTB (show SPTB Antibodies)).
High expression of CXCR3 is associated with glioblastoma patients with an invasive phenotype.
findings demonstrate that targeting CXCR3 is effective in both tumor and host compartments, and suggest that CXCR3 inhibition is likely to avoid adverse effects on host cells
Activation of the CXCL10 (show CXCL10 Antibodies)/CXCR3 pathway has an important role in retinal inflammation and neuronal injury after high intraocular pressure-induced ischemia.
STAT3 (show STAT3 Antibodies) in CD8 (show CD8A Antibodies)+ T Cells Inhibits Their Tumor Accumulation by Downregulating CXCR3/CXCL10 (show CXCL10 Antibodies) Axis
CXCR3-mediated trafficking of regulatory T cells could represent a mechanism of homeostatic immunoregulation during diabetogeneesis.
These studies identify CXCR3-mediated trafficking at the tumour vascular interface as a critical checkpoint to effective T-cell-based cancer immunotherapy.
activated T cells display a subtle distance-dependent chemotaxis toward clusters of infected cells and this is mediated by CXCR3 and its ligands.
results suggest that CXCR3 plays an important role in recruiting proinflammatory cells to the colon during colitis and that CXCR3 may be a therapeutic target to reduce the influx of proinflammatory cells in the inflamed colon.
MOG(1-125) immunization resulted in an increased incidence of severe experimental autoimmune encephalomyelitis and was accompanied by an increased percentage of CXCR3-expressing CD4 (show CD4 Antibodies)+ T cells producing IFNgamma in the CNS.
Data indicate that dipeptidylpeptidase 4 (DPP4 (show DPP4 Antibodies)) diminishes chemokine (show CCL1 Antibodies) CXCL10 (show CXCL10 Antibodies) expression and limits CXC Chemokine Receptor (show CXCR4 Antibodies) 3 (CXCR3)-mediated antitumor immunity.
Maternal CD8 (show CD8A Antibodies)+ T cells with fetal specificity upregulated expression of the chemokine receptor (show CCR1 Antibodies) CXCR3 and were essential for L. monocytogenes-induced fetal resorption in prenatal L. monocytogenes infection. CXCR3 knockout or blockade prevented this.
Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CXCR3 expression
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
chemokine (C-X-C motif) receptor 3
, C-X-C chemokine receptor type 3
, G protein-coupled receptor 9
, IP-10 receptor
, IP10 receptor
, Mig receptor
, chemokine (C-X-C) receptor 3
, interferon-inducible protein 10 receptor
, CXC chemokine receptor 3
, Interferon-inducible protein 10 receptor