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CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Additionally we are shipping CXCR3 Kits (40) and CXCR3 Proteins (7) and many more products for this protein.
Showing 10 out of 249 products:
Mouse (Murine) Monoclonal CXCR3 Primary Antibody for FACS - ABIN2660967
Krug, Uppaluri, Facchetti, Dorner, Sheehan, Schreiber, Cella, Colonna: IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation. in Journal of immunology (Baltimore, Md. : 1950) 2002
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Human Monoclonal CXCR3 Primary Antibody for FACS, ICFC - ABIN2662210
Aksoy, Yang, Ji, Reddy, Shahabuddin, Litvin, Rogers, Kelsen: CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation. in American journal of physiology. Lung cellular and molecular physiology 2006
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Mouse (Murine) Polyclonal CXCR3 Primary Antibody for IF (p), IHC (p) - ABIN678653
Zhang, Fei, Gao, Liu, Zhang: The role of CXCR3 in the induction of primary biliary cirrhosis. in Clinical & developmental immunology 2011
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Human Polyclonal CXCR3 Primary Antibody for EIA, FACS - ABIN951214
Zhou, Tang, Qin, Gayed, Li, Skokos, Kyriakides, Pober, Tellides: CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. in The Journal of experimental medicine 2010
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Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN1176889
Loetscher, Gerber, Loetscher, Jones, Piali, Clark-Lewis, Baggiolini, Moser: Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. in The Journal of experimental medicine 1997
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Human Polyclonal CXCR3 Primary Antibody for IHC, ELISA - ABIN1582555
Milićević, Miljković, Milićević, Labudović-Borović, Wang, Laan, Peterson, Randall, Westermann: Role of CCL19/21 and its possible signaling through CXCR3 in development of metallophilic macrophages in the mouse thymus. in Histochemistry and cell biology 2011
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Human Polyclonal CXCR3 Primary Antibody for ELISA, WB - ABIN334381
Martini, Zulian, Calabrese, Bortoli, Facco, Cabrelle, Valente, Zacchello, Agostini: CXCR3/CXCL10 expression in the synovium of children with juvenile idiopathic arthritis. in Arthritis research & therapy 2005
Human Polyclonal CXCR3 Primary Antibody for ELISA, WB - ABIN1535574
Marchese, Heiber, Nguyen, Heng, Saldivia, Cheng, Murphy, Tsui, Shi, Gregor: Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors. in Genomics 1996
CXCL10 (show CXCL10 Antibodies)/CXCR3 axis promotes gastric cancer cell invasion and migration by upregulating MMP-2 (show MMP2 Antibodies) and MMP-9 (show MMP9 Antibodies) production via PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) pathway.
CXCR3 expression in chronic lymphocytic leukemia cells was a strong determinant of a worse clinical outcome.
Speculate that aberrant expression of CXCR3 in marginal zone lymphoma of the skin is associated with migration of lymphoma cells to the epidermis and could lead to an epidermotropic pattern.
CXCR3 role in autoimmune thyroiditis [review]
Both CXCL10 (show CXCL10 Antibodies) and CXCR3 appeared to be useful in differentiating T1R reaction in borderline leprosy while CXCR3 alone differentiated BT from BT-T1R
CXCR3 expression was upregulated in advanced gastric cancer and was associated with increased CD4 (show CD4 Antibodies)+, CD8 (show CD8A Antibodies)+ tumor-infiltrating lymphocyte infiltration and improved overall survival
CXCR3 was also linked to steatosis through inducing hepatic lipogenic genes
congruent with the concept that inflammation plays a key role in the pathogenesis of LV dysfunction, MIG (show CXCL9 Antibodies), IP10 (show CXCL10 Antibodies) and I-TAC (show CXCL11 Antibodies) add diagnostic accuracy over and beyond NT-pro BNP (show BNC2 Antibodies).
Suggest that aberrant CXCR3 expression may play crucial roles in suppressing prostate carcinoma metastasis by inhibiting cell proliferation and invasion through the PCLbeta signaling pathway.
The expression of the chemokine (show CCL1 Antibodies) receptors CXCR3, CXCR4 (show CXCR4 Antibodies) and CXCR7 (show CXCR7 Antibodies) and their ligands.
Circulating levels of chemokines that activate CXCR3 are elevated in non-obese diabetic (NOD) mice, consistent with clinical findings in human diabetes.
CXCR3 interacts with IL-10 (show IL10 Antibodies) secreted by CD8 (show CD8A Antibodies)+CD122 (show IL2RB Antibodies)+ regulatory T cells in a mouse model of Acute Lung Injury and promotes interferon-gamma (show IFNG Antibodies) and CXCL10 (show CXCL10 Antibodies) release.
This study demonstrates a previously unrecognized role of CXCR3 signaling in glial cells in negatively regulating Th17 cell expansion during experimental autoimmune encephalomyelitis
findings demonstrate that targeting CXCR3 is effective in both tumor and host compartments, and suggest that CXCR3 inhibition is likely to avoid adverse effects on host cells
Activation of the CXCL10 (show CXCL10 Antibodies)/CXCR3 pathway has an important role in retinal inflammation and neuronal injury after high intraocular pressure-induced ischemia.
STAT3 (show STAT3 Antibodies) in CD8 (show CD8A Antibodies)+ T Cells Inhibits Their Tumor Accumulation by Downregulating CXCR3/CXCL10 (show CXCL10 Antibodies) Axis
CXCR3-mediated trafficking of regulatory T cells could represent a mechanism of homeostatic immunoregulation during diabetogeneesis.
These studies identify CXCR3-mediated trafficking at the tumour vascular interface as a critical checkpoint to effective T-cell-based cancer immunotherapy.
activated T cells display a subtle distance-dependent chemotaxis toward clusters of infected cells and this is mediated by CXCR3 and its ligands.
Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CXCR3 expression
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
chemokine (C-X-C motif) receptor 3
, C-X-C chemokine receptor type 3
, G protein-coupled receptor 9
, IP-10 receptor
, IP10 receptor
, Mig receptor
, chemokine (C-X-C) receptor 3
, interferon-inducible protein 10 receptor
, CXC chemokine receptor 3
, Interferon-inducible protein 10 receptor