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Chemokine (C-X-C Motif) Receptor 4 (CXCR4) ELISA Kits

CXCR4 encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. Additionally we are shipping CXCR4 Antibodies (351) and CXCR4 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CXCR4 12767 P70658
CXCR4 60628  
CXCR4 7852 P61073
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Top CXCR4 ELISA Kits at

Showing 10 out of 26 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.054 ng/mL 0.625-10 ng/mL 96 Tests Log in to see 9 to 11 Days
Rat 0.039 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 9 to 11 Days
Pig 0.059 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
Mouse 27 pg/mL 78.13-5000 pg/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 2 to 3 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days
0.156-10 ng/mL   96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days

Top referenced CXCR4 ELISA Kits

  1. Human CXCR4 ELISA Kit for Sandwich ELISA - ABIN417543 : Shanmugam, Manu, Ong, Ramachandran, Surana, Bist, Lim, Kumar, Hui, Sethi: Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model. in International journal of cancer. Journal international du cancer 2011 (PubMed)
    Show all 6 references for ABIN417543

  2. Rat (Rattus) CXCR4 ELISA Kit for Sandwich ELISA - ABIN367433 : Sato, Otani, Fujita, Shimazu, Yoshioka, Enoki, Minato, Iwasaka: Granulocyte colony-stimulating factor does not enhance recruitment of bone marrow-derived cells in rats with acute myocardial infarction. in Experimental and clinical cardiology 2013 (PubMed)

More ELISA Kits for CXCR4 Interaction Partners

Medaka Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. bilateral lineup in the trunk before PGC (show PGC ELISA Kits) migration colonizing gonadal areas is defective in PGCS expressing a missense mutation in chemokine receptor (show CCR1 ELISA Kits) gene cxcr4b

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. our present study provided evidence that SDF-1 (show CXCL12 ELISA Kits) mediated CSCs migration through CXCR4 and CXCR7 (show CXCR7 ELISA Kits) via MEK (show MDK ELISA Kits)/ERK (show EPHB2 ELISA Kits) and PI3K/Akt (show AKT1 ELISA Kits) pathway

  2. Endothelial CXCR4 is negatively regulated by miR (show MLXIP ELISA Kits)-139-5p, whose transcription is in turn induced by laminar flow and APLN (show APLN ELISA Kits)/APLNR (show APLNR ELISA Kits) signalling.

  3. CXCR4 signaling has a role in radiation-induced lung damage that promotes breast cancer lung-metastasis

  4. Splenic TFF2 (show TFF2 ELISA Kits), a secreted anti-inflammatory peptide, is released by vagally modulated memory T cells to suppress the expansion of myeloid-derived suppressor cells through CXCR4.

  5. CXCR4 inhibitor attenuates allergen-induced lung inflammation by down-regulating MMP-9 (show MMP9 ELISA Kits) and ERK1/2 (show MAPK1/3 ELISA Kits) expression.

  6. CXCR4 regulates the acquisition of an EMT (show ITK ELISA Kits)-like phenotype in extra-medullary myeloma. CXCR4 silencing leads to reduced tumor growth.

  7. Dimethyloxalylglycine up-regulates myocardial CXCR4 expression to improve cardiac function in myocardial infarction.

  8. The estradiol-CXCL12 (show CXCL12 ELISA Kits)/CXCR4 signaling pathway may be useful in determining treatments for endometrial disorders, and may be antagonized to block stem cell migration to endometriosis.

  9. results suggest a novel mechanism whereby the local activation of CCR2 (show CCR2 ELISA Kits) on monocytes in the bone marrow attenuates an anchoring signalling provided by CXCR4 expressed by the same cell and mobilizes the bone marrow monocyte to the blood stream

  10. Revealed comparable numbers of hair follicles (HFs) forming in knockout embryos compared to wild-type littermate controls, suggesting that neither dermal nor epithelial Cxcr4 expression is required for early HF morphogenesis.

Human Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. Its remarkable effect on inhibiting CXCR4/CXCL12 (show CXCL12 ELISA Kits)-mediated adhesion and migration of AML (show RUNX1 ELISA Kits) cells.

  2. Evidences suggest an indispensable role of GLI1 (show GLI1 ELISA Kits) in the migration and metastasis of breast cancer cells through CXCL12 (show CXCL12 ELISA Kits)/CXCR4 signaling enhancement.

  3. Data suggest that sequenced administration of CXCR4 receptor antagonists with cytotoxic chemotherapy synergize to reduce distant metastases.

  4. Blood fibrocytes are recruited during COPD (show ARCN1 ELISA Kits) exacerbations and related to mortality and low lung function. The CXCL12 (show CXCL12 ELISA Kits)/CXCR4 axis is involved in such fibrocyte recruitment.

  5. chemokine receptor CXCR4 is targeted by peptide Nef-M1, which inhibits tumor angiogenesis and epithelialtomesenchymal transition in colon and breast cancers

  6. Synovial SDF-1 (show CXCL12 ELISA Kits) correlated with disease activity, and its receptor CXCR4 was related to joint destruction in rheumatoid arthritis patients treated with golimumab.

  7. CXCR4 signaling has a role in radiation-induced lung damage that promotes breast cancer lung-metastasis

  8. there is an elevation in CXCR4 and a decrease in SSTR2A expression with increasing malignancy in gastroenteropancreatic neuroendocrine neoplasms

  9. CXCR4 siRNA prohibited SDF-1 (show CXCL12 ELISA Kits)-induced AKT (show AKT1 ELISA Kits) and ERK (show EPHB2 ELISA Kits) phosphorylation, at the same time, EMT (show ITK ELISA Kits) biomarker changes were not observed. The SDF-1 (show CXCL12 ELISA Kits)/CXCR4 axis triggers EMT (show ITK ELISA Kits), tumor cell invasion and proliferation via activation of PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) and ERK (show EPHB2 ELISA Kits) pathways.

  10. This study demonstrates that the effects of CXCR4 inhibition on blast suppression and immune cell function in the tumor microenvironment and chemotherapy with plerixafor represents an advanced therapeutic strategy of targeting the leukemic niche.

Pig (Porcine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. CXCR4 controls leukocyte mobilization after trauma.

  2. The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1 (show CXCL12 ELISA Kits)/CXCR4 axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.

  3. reports transmural and perivascular expression patterns of chemokines CCL2 (show CCL2 ELISA Kits) and CXCL2 (show CXCL2 ELISA Kits) and of chemokine (show CCL1 ELISA Kits) receptors CCR2 (show CCR2 ELISA Kits), CCR5 (show CCR5 ELISA Kits), and CXCR4 following coronary angioplasty

Xenopus laevis Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. There is a potential link between follicular SDF1 (show CXCL12 ELISA Kits)/CXCR4 activation and the regulation of ovulation-related genes in cows and horses.

  2. The combination of low expression of CXCR4 and high expression of IL-10 (show IL10 ELISA Kits) might be closely concerned with some bias for the production of PI calves.

Rhesus Monkey Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. The increased CXCR4 and CXCR7 (show CXCR7 ELISA Kits) expression resulted in increased SDF-1 (show CXCL12 ELISA Kits)-induced RF/6A cell migration and tube formation.

  2. The CXCR7 (show CXCR7 ELISA Kits)/CXCR4/CXCL12 (show CXCL12 ELISA Kits) axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.

  3. These findings suggest that FBLN5 (show FBLN5 ELISA Kits) may interfere with choroidal neovascularization by downregulating VEGF (show VEGFA ELISA Kits), CXCR4, and TGFB1 (show TGFB1 ELISA Kits) expression and inhibiting choroidl endothelial cell proliferation.

  4. Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 (show CCR5 ELISA Kits) and CXCR4 for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 almost exclusively

Zebrafish Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. Arteries are formed by vein-derived endothelial tip cells, this process critically depends on chemokine receptor Cxcr4 function.

  2. SDF1a (show CXCL12 ELISA Kits) directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (show CXCR7 ELISA Kits).

  3. Hoxb8a is induced by and cooperates with Wnt (show WNT2 ELISA Kits) signaling to up-regulate cxcr4b, and acts through multiple mechanisms to repress cxcr7b expression.

  4. Expression of Cxcr4 and Cxcl12 (show CXCL12 ELISA Kits) in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12 (show CXCL12 ELISA Kits)/Cxcr4 pair in brain development and functioning.

  5. show that inactivation of the estrogen receptor ESR1 (show ESR1 ELISA Kits) results in ectopic expression of cxcr4b throughout the primordium, whereas ESR1 (show ESR1 ELISA Kits) overexpression results in a reciprocal reduction in the domain of cxcr4b expression.

  6. Study suggest that the Cxcl12a-Cxcr4b ligand-receptor pair are involved in the migration of GnRH3 neurons in zebrafish, and are therefore crucial for the development of this system.

  7. A CXCR4-like chemokine receptor (show CCR1 ELISA Kits) is expressed by the migrating lateral line primordium cells. Both the formation and the innervation of this system depend on the SDF1 (show CXCL12 ELISA Kits)-CXCR4 system.

  8. Knocking down CXCR4 results in severe defects in primordial germ cell migration.

  9. SDF-1 (show CXCL12 ELISA Kits)/CXCR4 signaling is important for guiding retinal ganglion cell axons within the retina to the optic stalk to exit the retina.

  10. chemokine (show CCL1 ELISA Kits) signaling contributes to both the olfactory placode assembly and the olfactory sensory neurons axon pathfinding in zebrafish

CXCR4 Antigen Profile

Antigen Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with CXCR4

  • chemokine (C-X-C motif) receptor 4 (cxcr4) antibody
  • chemokine (C-X-C motif) receptor 4 (CXCR4) antibody
  • chemokine (C-X-C motif) receptor 4 (Cxcr4) antibody
  • chemokine (C-X-C motif) receptor 4 (cxcr4-b) antibody
  • chemokine (C-X-C motif), receptor 4b (cxcr4b) antibody
  • neuropeptide Y receptor type 3 (CXCR4) antibody
  • cb403 antibody
  • CD184 antibody
  • Cmkar4 antibody
  • CXC-R4 antibody
  • CXC-R4-B antibody
  • CXCR-4 antibody
  • CXCR-4-B antibody
  • CXCR4 antibody
  • D2S201E antibody
  • FB22 antibody
  • HM89 antibody
  • HSY3RR antibody
  • LAP3 antibody
  • LCR1 antibody
  • LESTR antibody
  • NPY3R antibody
  • NPYR antibody
  • NPYRL antibody
  • NPYY3R antibody
  • PB-CKR antibody
  • PBSF/SDF-1 antibody
  • Sdf1r antibody
  • WHIM antibody
  • xcxcr4 antibody
  • zgc:109863 antibody

Protein level used designations for CXCR4

C-X-C chemokine receptor type 4 , SDF-1 receptor , Stromal cell-derived factor 1 receptor , chemokine (C-X-C motif) receptor 4 , CXC-R4 , CXCR-4 , chemokine (C-X-C) receptor 4 , chemokine receptor 4 , fusin , leukocyte-derived seven transmembrane domain receptor , leukocyte-expressed seven-transmembrane-domain , pre-B-cell-derived chemokine receptor , stromal cell-derived factor 1 receptor , CXC chemokine receptor , LESTR , chemokine receptor (LCR1) , CD184 antigen , leukocyte-derived seven-transmembrane-domain receptor , lipopolysaccharide-associated protein 3 , neuropeptide Y receptor Y3 , seven transmembrane helix receptor , seven-transmembrane-segment receptor, spleen , C-X-C chemokine receptor type 4-B , SDF-1 receptor B , SDF-1 receptor-B , Stromal cell-derived factor 1 receptor-B , stromal cell-derived factor 1 receptor B , LCR1 , chemokine receptor CXCR4 , CXC chemokine receptor 4 , ody , odysseus

100038176 Xenopus (Silurana) tropicalis
100049444 Oryzias latipes
100346189 Oryctolagus cuniculus
100451032 Pongo abelii
100604120 Nomascus leucogenys
12767 Mus musculus
60628 Rattus norvegicus
7852 Homo sapiens
396659 Sus scrofa
380373 Xenopus laevis
281736 Bos taurus
493676 Felis catus
483900 Canis lupus familiaris
707329 Macaca mulatta
395324 Gallus gallus
100126711 Papio anubis
450130 Pan troglodytes
114447 Danio rerio
443532 Ovis aries
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