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anti-Chemokine (C-C Motif) Receptor 8 (CCR8) Antibodies

CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Additionally we are shipping CCR8 Kits (10) and CCR8 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCR8 1237 P51685
CCR8 12776 P56484
CCR8 301066  
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Top anti-CCR8 Antibodies at antibodies-online.com

Showing 10 out of 137 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, WB CCR8 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CCR8 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the CCR8 antibody detected the CCR8 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rat PE FACS Detection of CCR8 in Rat Splenocytes by Flow Cytometry. Rat splenocytes were stained with Rat Anti-Human/Rat CCR8 PE-conjugated Monoclonal Antibody. Detection of CCR8 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human Integrin alpha M/CD11b Alexa Fluor 488-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details
Human Rat Allophycocyanin FACS Detection of CCR8 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Rat Anti-Human/Rat CCR8 APC-conjugated Monoclonal Antibody. Detection of CCR8 in Rat Peripheral Blood Cells by Flow Cytometry. Rat peripheral blood cells were stained with Rat Anti-Human/Rat CCR8 APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$140.70
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CCR8 Antibody Titration: 2.5ug/mlPositive Control: K562 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: CCR8 Antibody [NLS3847] - Analysis of anti-CCR8 antibody with human lymph node, non-Hodgkins lymphoma. Immunohistochemistry-Paraffin: CCR8 Antibody [NLS3847] - Analysis of anti-CCR8 antibody with tonsil, germinal center at 22 ug/ ml. 0.05 mL Log in to see 7 to 9 Days
$447.56
Details
Mouse Goat Un-conjugated IHC (p), IHC, ELISA, WB Immunohistochemistry on paraffin section of mouse spleen 0.1 mg Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$434.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: CCR8 Antibody [NLS359] - Analysis of anti-CCR8 antibody with human tonsil, germinal center at 3 ug/ml. 0.05 mL Log in to see 10 to 13 Days
$447.56
Details
Human Rat PerCP FACS Detection of CCR8 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Rat Anti-Human/Rat CCR8 PerCP-conjugated Monoclonal Antibody. Detection of CCR8 in Rat Peripheral Blood Cells by Flow Cytometry. Rat peripheral blood cells were stained with Rat Anti-Human/Rat CCR8 PerCP-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$140.70
Details
Human Rabbit Un-conjugated FACS, WB CCR8 Antibody (C-term) (ABIN654442) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details

CCR8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CCR8 Antibodies

  1. Human Polyclonal CCR8 Primary Antibody for EIA, FACS - ABIN951452 : Mutalithas, Guillen, Raport, Kolbeck, Soler, Brightling, Pavord, Wardlaw: Expression of CCR8 is increased in asthma. in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010 (PubMed)
    Show all 5 references for ABIN951452

  2. Human Monoclonal CCR8 Primary Antibody for FACS - ABIN4895443 : Oo, Weston, Lalor, Curbishley, Withers, Reynolds, Shetty, Harki, Shaw, Eksteen, Hubscher, Walker, Adams: Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 4 references for ABIN4895443

  3. Mouse (Murine) Polyclonal CCR8 Primary Antibody for IHC (p), IHC - ABIN152132 : Liu, Cao, Tang, Liu, Tang: CCR7, CCR8, CCR9 and CCR10 in the mouse hippocampal CA1 area and the dentate gyrus during and after pilocarpine-induced status epilepticus. in Journal of neurochemistry 2007 (PubMed)
    Show all 2 references for ABIN152132

  4. Human Monoclonal CCR8 Primary Antibody for FACS - ABIN4895439 : Ahern, Lloyd, Robinson: Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors. in Allergy 2009 (PubMed)
    Show all 2 references for ABIN4895439

  5. Human Polyclonal CCR8 Primary Antibody for WB - ABIN319016 : Goya, Gutiérrez, Varona, Kremer, Zaballos, Márquez: Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)

  6. Human Polyclonal CCR8 Primary Antibody for IHC (p) - ABIN4289263 : Pacheco-Rodriguez, Kumaki, Steagall, Zhang, Ikeda, Lin, Billings, Moss: Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

  7. Human Polyclonal CCR8 Primary Antibody for IHC (p) - ABIN270974 : Brix, Stege, Disteldorf, Hoxha, Krebs, Krohn, Otto, Klätschke, Herden, Heymann, Lira, Tacke, Wolf, Busch, Jabs, Özcan, Keller, Beige, Wagner, Helmchen, Noriega, Wiech, Panzer, Stahl: CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN. in Journal of the American Society of Nephrology : JASN 2015 (PubMed)

  8. Cow (Bovine) Polyclonal CCR8 Primary Antibody for WB - ABIN2792241 : Haque, Fallon, Pan, Taubman, Harpel: Chemokine receptor-8 (CCR8) mediates human vascular smooth muscle cell chemotaxis and metalloproteinase-2 secretion. in Blood 2004 (PubMed)

More Antibodies against CCR8 Interaction Partners

Human Chemokine (C-C Motif) Receptor 8 (CCR8) interaction partners

  1. Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor (show CCR1 Antibodies) CCR8 for Chemokine (show CCL1 Antibodies) and Small Molecule Binding.

  2. High CCR8 expression is associated with high recurrence in kidney cancer.

  3. findings suggest that CCR8 expression in ALCL is more closely related to the presence of DUSP22 (show DUSP22 Antibodies) rearrangements than to cutaneous involvement and that the function of CCR8 may extend beyond its skin-homing properties in this disease

  4. Epidermal-derived vitamin D3 metabolites and prostaglandins provide an essential cue for the localization of CCR8+ immune surveillance T cells within healthy human skin.

  5. CCL1 (show CCL1 Antibodies)-CCR8 interaction may play a critical role in lymphocytic recruitment in IgG4-related sclerosing cholangitis and type 1 autoimmune pancreatitis, leading to duct-centred inflammation and obliterative phlebitis.

  6. Identification of human CCR8 as a CCL18 (show CCL18 Antibodies) receptor.

  7. CCR8(+) myeloid cell subset is expanded in patients with cancer.

  8. Data show that CCR8 expression by newly activated naive T cells is regulated by skin-specific factor(s) derived primarily from epidermal keratinocytes.

  9. C-terminal clipping of chemokine CCL1 (show CCL1 Antibodies)/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity

  10. The functional data from human macrophages suggest a potential cross talk between the CCR8 and the Toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) pathways, both of which are present in chronic obstructive pulmonary disease patients.

Mouse (Murine) Chemokine (C-C Motif) Receptor 8 (CCR8) interaction partners

  1. CCR8 negatively regulates migration of cutaneous dendritic cells from the skin to the draining lymph nodes in contact hypersensitivity by keeping these cells in the skin.

  2. Chemokine receptor (show CCR1 Antibodies) CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages.

  3. A sustained donor Treg presence is critical for their beneficial properties, and that their survival depends on CCR8 and donor but not host CD11c (show ITGAX Antibodies)(+) Aantigen presenting cells.

  4. Expression of CCR-8 in microglia was upregulated in the presence of CCL-1 (show CCL1 Antibodies).

  5. C-terminal clipping of chemokine CCL1 (show CCL1 Antibodies)/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity

  6. Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor (show CCR1 Antibodies) C-C motif chemokine receptor 8 in mice.

  7. a key regulator of Th2 cell skin recruitment during IL-5 (show IL5 Antibodies)-mediated allergic inflammation

  8. mediates increased responsiveness of murine eosinophils to TCA-3 (show CCL1 Antibodies)

  9. Data from three different models plus an in vivo blocking study clearly show that the Th2 cell-mediated pathological response to ovalbumin (show OVA Antibodies)-induced allergic airway inflammation is not critically CCR8-dependent.

  10. sulfation at specific positions of the N-terminal domain of mouse CCR8 is critical for its biological activity, whereas glycosylation has a minor influence

CCR8 Antigen Profile

Protein Summary

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

Gene names and symbols associated with CCR8

  • C-C chemokine receptor 8 like (CCR8L) antibody
  • chemokine (C-C motif) receptor 8 (CCR8) antibody
  • chemokine (C-C motif) receptor 8 (Ccr8) antibody
  • chemokine (C-C motif) receptor 8 (LOC100345500) antibody
  • C-C antibody
  • C-C CKR-8 antibody
  • CC-CKR-8 antibody
  • CCR-8 antibody
  • CCR8 antibody
  • CCR8-L antibody
  • CDw198 antibody
  • CKR-8 antibody
  • CKRL1 antibody
  • Cmkbr8 antibody
  • CMKBRL2 antibody
  • CY6 antibody
  • GPRCY6 antibody
  • mCCR8 antibody
  • TER1 antibody

Protein level used designations for CCR8

chemokine (C-C motif) receptor 8 , C-C chemokine receptor type 8 , CC chemokine receptor 8 , CC chemokine receptor CHEMR1 , CC-chemokine receptor chemr1 , chemokine (C-C) receptor 8 , chemokine (C-C) receptor-like 2 , chemokine receptor-like 1 , C-C motif chemokine receptor 8

GENE ID SPECIES
776400 Gallus gallus
1237 Homo sapiens
407772 Bos taurus
12776 Mus musculus
301066 Rattus norvegicus
420718 Gallus gallus
693806 Macaca mulatta
100345500 Oryctolagus cuniculus
100725278 Cavia porcellus
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