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CCRL2 encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Additionally we are shipping CCRL2 Proteins (4) and CCRL2 Kits (1) and many more products for this protein.
Showing 10 out of 89 products:
Human Polyclonal CCRL2 Primary Antibody for EIA, WB - ABIN951139
Zabel, Nakae, Zúñiga, Kim, Ohyama, Alt, Pan, Suto, Soler, Allen, Handel, Song, Galli, Butcher: Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis. in The Journal of experimental medicine 2008
Show all 5 references for ABIN951139
Human Monoclonal CCRL2 Primary Antibody for FACS - ABIN2662410
Yoshimura, Oppenheim: Chemokine-like receptor 1 (CMKLR1) and chemokine (C-C motif) receptor-like 2 (CCRL2); two multifunctional receptors with unusual properties. in Experimental cell research 2011
Show all 4 references for ABIN2662410
Human Monoclonal CCRL2 Primary Antibody for FACS - ABIN4899082
Hartmann, Leick, Ewers, Diefenbacher, Schraufstatter, Honczarenko, Burger: Human B cells express the orphan chemokine receptor CRAM-A/B in a maturation-stage-dependent and CCL5-modulated manner. in Immunology 2008
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Cow (Bovine) Polyclonal CCRL2 Primary Antibody for WB - ABIN2778230
Galligan, Matsuyama, Matsukawa, Mizuta, Hodge, Howard, Yoshimura: Up-regulated expression and activation of the orphan chemokine receptor, CCRL2, in rheumatoid arthritis. in Arthritis and rheumatism 2004
Human Polyclonal CCRL2 Primary Antibody for IF, ELISA - ABIN1535572
Muzny, Scherer, Kaul, Wang, Yu, Sudbrak, Buhay, Chen, Cree, Ding, Dugan-Rocha, Gill, Gunaratne, Harris, Hawes, Hernandez, Hodgson, Hume, Jackson, Khan, Kovar-Smith, Lewis, Lozado, Metzker et al.: The DNA sequence, annotation and analysis of human chromosome 3. ... in Nature 2006
CCRL2 inhibited the growth of breast cancer cells in vitro and in vivo.
in breast cancer, CRAM-A becomes specifically upregulated under inflammatory stimuli and may serve as a potential marker of immune response.
these results suggest for the first time that elevated CCRL2 in glioma promotes cell migration and invasion.
Considering the newly defined role of CCRL2 in lung dendritic cell trafficking, this atypical chemokine receptor (show CCR1 Antibodies) may affect pneumocystis pneumonia through immune regulation and inducing inflammation.
demonstration that the homeostatic chemokine CCL19 (show CCL19 Antibodies) is a specific ligand for CRAM
CCRL2 expression is up-regulated on synovial neutrophils of rheumatoid arthritis patients
Results identify chemerin (show RARRES2 Antibodies) as a natural nonsignaling protein ligand for both human and mouse CCRL2.
Proinflammatory stimuli upregulate atypical chemerin receptor (show CMKLR1 Antibodies) CCRL2 and VCAM-1 (show VCAM1 Antibodies) on endothelial cells via NF-kappaB (show NFKB1 Antibodies) and JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) intracellular signaling pathways.
Ccrl2(-/-) mice showed normal recruitment of circulating dendritic cells (DC) into the lung, but a defective trafficking of antigen-loaded lung DC to mediastinal lymph nodes.
Expression of L-CCR mRNA is reported in murine astrocytes and microglia and is greatly enhanced under proinflammatory conditions; this receptor may play a role in neuroinflammatory processes.
Prominent expression of L-CCR mRNA is detected in astrocytes and microglia at early time points throughout the brain and spinal cord in experimental autoimmune encephalomyelitis supporting the proposed relationship of L-CCR expression to CNS inflammation.
This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.
C-C chemokine receptor-like 2
, chemokine (C-C motif) receptor-like 2
, c-C chemokine receptor-like 2-like
, atypical chemokine receptor 5
, chemokine receptor CCR11
, chemokine receptor X
, putative MCP-1 chemokine receptor
, G-protein coupled beta chemokine receptor
, chemokine (C-C) receptor 1,-like 2
, chemokine (C-C) receptor 1-like 2
, lipopolysaccharide inducible C-C chemokine receptor related
, lipopolysaccharide-inducible C-C chemokine receptor
, lipopolysacharide-inducible C-C chemokine receptor
, chemokine C-C motif receptor-like 2