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Chemokine (C-X3-C Motif) Ligand 1 Proteins (CX3CL1)

Chemotactic factor. Additionally we are shipping CX3CL1 Antibodies (227) and CX3CL1 Kits (79) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CX3CL1 110894  
CX3CL1 89808 O55145
CX3CL1 6376 P78423
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Top CX3CL1 Proteins at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Cynomolgus Fc Tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Dog Fc Tag 50 μg Log in to see 16 Days
$382.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   10 μg Log in to see 10 to 12 Days
$135.88
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$583.00
Details
HOST_HEK-293 Cells Human His tag,Biotin Biotinylated Human CX3CL1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 200 μg Log in to see 5 Days
$1,545.50
Details

CX3CL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , ,
,
Rat (Rattus) ,

Human , , , , , ,
, , , , ,

Top referenced CX3CL1 Proteins

  1. Rat (Rattus) CX3CL1 Protein expressed in Escherichia coli (E. coli) - ABIN2666797 : Hundhausen, Misztela, Berkhout, Broadway, Saftig, Reiss, Hartmann, Fahrenholz, Postina, Matthews, Kallen, Rose-John, Ludwig: The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. in Blood 2003 (PubMed)
    Show all 8 references for ABIN2666797

  2. Human CX3CL1 Protein expressed in Escherichia coli (E. coli) - ABIN2666622 : Hamann, Unterwalder, Cardona, Meisel, Zipp, Ransohoff, Infante-Duarte: Analyses of phenotypic and functional characteristics of CX3CR1-expressing natural killer cells. in Immunology 2011 (PubMed)
    Show all 7 references for ABIN2666622

  3. Mouse (Murine) CX3CL1 Protein expressed in Escherichia coli (E. coli) - ABIN2666624 : Hundhausen, Schulte, Schulz, Andrzejewski, Schwarz, von Hundelshausen, Winter, Paliga, Reiss, Saftig, Weber, Ludwig: Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 7 references for ABIN2666624

  4. Human CX3CL1 Protein expressed in Human Cells - ABIN2003167 : Bazan, Bacon, Hardiman, Wang, Soo, Rossi, Greaves, Zlotnik, Schall: A new class of membrane-bound chemokine with a CX3C motif. in Nature 1997 (PubMed)
    Show all 3 references for ABIN2003167

  5. Human CX3CL1 Protein expressed in Escherichia coli (E. coli) - ABIN666659 : Papadopoulos, Sassetti, Saeki, Yamada, Kawamura, Fitzhugh, Saraf, Schall, Blauvelt, Rosen, Hwang: Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation. in European journal of immunology 1999 (PubMed)
    Show all 2 references for ABIN666659

  6. Cynomolgus CX3CL1 Protein expressed in Human Cells - ABIN2010151 : Imai, Hieshima, Haskell, Baba, Nagira, Nishimura, Kakizaki, Takagi, Nomiyama, Schall, Yoshie: Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. in Cell 1997 (PubMed)
    Show all 2 references for ABIN2010151

More Proteins for Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) Interaction Partners

Mouse (Murine) Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) interaction partners

  1. Authors provide evidence that interactions between CX3CL1 and CX3CR1 (show CX3CR1 Proteins) play crucial roles in determining the number of M1 macrophages within the skin of mice, which in turn can have dramatic effects on psoriasis-like inflammation.

  2. In the absence of the rd8 allele, deficiency of CCR2 (show CCR2 Proteins) and CX3CL1 in mice leads to a mild form of retinal degeneration which is associated with the recruitment of macrophages, particularly to the subretinal space. This model enables to assess consequences of perturbed chemokine (show CCL1 Proteins) signaling, but it does not recapitulate cardinal (show CARD8 Proteins) age-related macular degeneration features.

  3. Also icariin reduced CX3CR1 (show CX3CR1 Proteins) and CX3CL1 protein levels in the artery wall. In conclusion, icariin could be a potential anti-atherosclerosis agent by downregulating the expression of CX3CR1 (show CX3CR1 Proteins).

  4. The biological activity of CX3CL1 is regulated by conversion of a membrane integrated to a soluble form during neurogenesis and in response to pathologic changes in the adult retinal milieu.

  5. CX3CL1/CX3CR1 (show CX3CR1 Proteins) signaling is involved in LTP (show SCP2 Proteins) of C-fiber-evoked field potentials in the rodent spinal dorsal horn

  6. CX3CL1/CX3CR1-mediated microglial activation plays a detrimental role in ischemic brain via p38MAPK/PKC signaling

  7. Cx3cl1 overexpression suppresses alpha-synuclein-mediated neurodegeneration.

  8. IFN-gamma (show IFNG Proteins) induces aberrant CD49b (show ITGA2 Proteins)+ NK cell recruitment and pregnancy failure through regulating CX3CL1.

  9. tumours are characterized by expression of inflammatory chemokines (CCL2 (show CCL2 Proteins), CCL5 (show CCL5 Proteins), CCL7 (show CCL7 Proteins), CCL8 (show CCL8 Proteins), CCL12 (show Ccl12 Proteins), CXCL9 (show CXCL9 Proteins), CXCL10 (show CXCL10 Proteins) and CX3CL1), reflected by an enrichment of activated Foxp3 (show FOXP3 Proteins)(-) and Foxp3 (show FOXP3 Proteins)(+) T cells

  10. Insulin (show INS Proteins) resistance increases plaque vulnerability by augmenting the CX3CL1/CX3CR1 (show CX3CR1 Proteins) axis, which is mechanistically linked to reduced vascular smooth muscle cell survival

Human Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) interaction partners

  1. CX3CL1 exerts numerous effects on pathophysiological conditions that have both negative and positive consequences on pathogenesis and outcome [review]

  2. XCL2 (show XCL2 Proteins) and CX3CL1 expression in lung cancers and adjacent non-cancerous tissues was detected by quantitative PCR and ELISA. The expression of XCL2 (show XCL2 Proteins) and CX3CL1 increases with increasing degree of malignancy, indicating that both chemokines might be important targets in gene therapy for lung cancer.

  3. Recent works show that, in allergic diseases, there is an increased expression of fractalkine/CX3CL1 and its unique receptor CX3CR1 (show CX3CR1 Proteins) and that this chemokine (show CCL1 Proteins) does not act as chemoattractant. In allergic asthma, CX3CR1 (show CX3CR1 Proteins) expression regulates Th2 and Th1 (show TH1L Proteins) cell survival in the inflammatory lung, while, in atopic dermatitis, it regulate Th2 and Th1 (show TH1L Proteins) cell retention into the inflammatory site. [review]

  4. Post-transcriptional suppression of KSRP (show KHSRP Proteins) destabilizes CX3CL1 mRNA in liver epithelial cells.

  5. CX3CL1 increased the migration and invasiveness of DU145 and PC-3 (show PCSK1 Proteins), causing epithelial-to-mesenchymal transition. TACE (show ADAM17 Proteins)/TGF-alpha (show TGFA Proteins)/EGFR (show EGFR Proteins) pathway activation and Slug (show SNAI2 Proteins) upregulation were responsible for this.

  6. Cell proliferation enhancing and anti-apoptosis activity requires the intracellular domain and apparently the dimerization of the transmembrane chemokine (show CCL1 Proteins) ligand.

  7. CX3CL1 was expressed only by the normal and cancer adjacent normal fallopian tube epithelium; its expression was largely lost in the malignant fallopian epithelium.

  8. Skin and serum CX3CL1 elevated expression was associated with psoriasis severity.

  9. CX3CL1(+) apo (show C9orf3 Proteins)-MPs released by apoptotic cells mediate the chemotactic transmigration of alveolar macrophages.

  10. Suggest that CX3CL1 participates in cross-talk mechanisms between endothelium and other muscle tissue cells and may promote a shift in the microenvironment toward a more regenerative milieu after exercise.

CX3CL1 Protein Profile

Protein Summary

Chemotactic factor. Binds to CX3CR1.

Gene names and symbols associated with CX3CL1

  • chemokine (C-X3-C motif) ligand 1 (CX3CL1)
  • chemokine (C-X3-C motif) ligand 1, related sequence 1 (Cx3cl1-rs1)
  • chemokine (C-X3-C motif) ligand 1 (LOC100346186)
  • chemokine (C-X3-C motif) ligand 1 (Cx3cl1)
  • AB030188 protein
  • ABCD-3 protein
  • AI848747 protein
  • C3Xkine protein
  • CX3C protein
  • Cx3C-rs1 protein
  • CX3CL1 protein
  • CXC3 protein
  • CXC3C protein
  • D8Bwg0439e protein
  • DKFZp459K117 protein
  • fractalkine protein
  • neurotactin protein
  • NTN protein
  • NTT protein
  • SCYD1 protein
  • Scyd1-rs1 protein

Protein level used designations for CX3CL1

chemokine CX3CL1/FRACTALKINE , fractalkine , chemokine (C-X3-C motif) ligand 1 , chemokine (C-X3-C motif) ligand 1, related sequence 1 , small inducible cytokine subfamily D, 1-related sequence 1 , CX3CL1 chemokine , C-X3-C motif chemokine 1 , CX3C membrane-anchored chemokine , neurotactin , small inducible cytokine subfamily D, 1 , small-inducible cytokine D1 , small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin) , small inducible cytokine subfamily D (Cys-X3-Cys), member-1

GENE ID SPECIES
574225 Macaca mulatta
454115 Pan troglodytes
100037930 Sus scrofa
100172425 Pongo abelii
110894 Mus musculus
415651 Gallus gallus
100346186 Oryctolagus cuniculus
100582586 Nomascus leucogenys
89808 Rattus norvegicus
20312 Mus musculus
6376 Homo sapiens
487265 Canis lupus familiaris
517354 Bos taurus
101119927 Ovis aries
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