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The protein encoded by CHI3L2 is similar to bacterial chitinases but lacks chitinase activity. Additionally we are shipping Chitinase 3-Like 2 Antibodies (65) and Chitinase 3-Like 2 Kits (5) and many more products for this protein.
Showing 5 out of 7 products:
Human CHI3L2 Protein expressed in Human Cells - ABIN2005077
Hu, Trinh, Figueira, Price: Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family. in The Journal of biological chemistry 1996
Show all 3 references for ABIN2005077
This review comprehensively analyzes recent data about expression pattern, and involvement of human YKL-40 (show CHI3L1 Proteins), YKL-39 and SI-CLP (show CHID1 Proteins) in cancer. [review]
cerebrospinal fluid CHI3L1 (show CHI3L1 Proteins) and CHI3L2 and serum CHI3L1 (show CHI3L1 Proteins) might help to define multiple sclerosis disease stage
Structural analysis demonstrates that YKL-39 interacts with chitooligosaccharides through hydrogen bonds and hydrophobic interactions. Thermodynamic analysis indicates that binding of chitooligosaccharide to YKL-39 is mainly driven by enthalpy.
YKL-39 possesses a chitinase-like fold, but lacks key active-site residues required for catalysis.
ERK1/2 phosphorylation by CHI3L2 inhibits cell mitogenesis and proliferation.
human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40 (show CHI3L1 Proteins)) is upregulated in osteoarthritic cartilage
The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene.
chitinase-3-like protein 2
, chondrocyte protein 39