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Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Additionally we are shipping Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies (106) and Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins (24) and many more products for this protein.
Showing 10 out of 68 products:
Human CHI3L1 ELISA Kit for Sandwich ELISA - ABIN414711
Erfan, Guzel, Alpsoy, Rifaioglu, Kaya, Kucukyalc?n, Topcu, Kulac: Serum YKL-40: a potential biomarker for psoriasis or endothelial dysfunction in psoriasis? in Molecular and cellular biochemistry 2015
Show all 4 Pubmed References
Human CHI3L1 ELISA Kit for Sandwich ELISA - ABIN577524
Zhang, Peng, Cheng, Shi, Zhang, Xu: Paeoniflorin Atttenuates Amyloidogenesis and the Inflammatory Responses in a Transgenic Mouse Model of Alzheimer's Disease. in Neurochemical research 2015
CHI3L1-mediated cell proliferation/survival involves partial downregulation of the pro-apoptotic S100A9 (show S100A9 ELISA Kits) protein that is highly expressed during the acute phase of colitis, by binding to the S100A9 (show S100A9 ELISA Kits) receptor, RAGE (show AGER ELISA Kits) (Receptor for Advanced Glycation End products).
IL-18 (show IL18 ELISA Kits) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (show IL18 ELISA Kits)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.
CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.
Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.
Results do not support a role of BRP (show GDF5 ELISA Kits)-39 in the pathogenesis of experimental autoimmune encephalitis.
CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.
mechanism of BRP (show GDF5 ELISA Kits)-39 in bleomycin-induced pulmonary fibrosis
Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis
Data show that IL-1 (show IL1A ELISA Kits)-induced transcriptin factor RelB (show RELB ELISA Kits)/NF-kappa B p50 (show NFKB1 ELISA Kits) Subunit complex formation was further promoted by oncostatin M (show OSM ELISA Kits) and that these complexes directly bound to the secreted protein cartilage glycoprotein 39 (YKL-40) promoter.
These results indicate that catalytically inactive BRP (show GDF5 ELISA Kits)-39 and Ym1 (show CHI3L3 ELISA Kits) are constitutive genes in normal mouse lung.
SNPs in CHI3L1 and cord blood YKL-40 were not associated with lung function measurements at 5 weeks and 6 years, respiratory symptoms in the first year, and allergic sensitisation at 6 years. Genetic variation in CHI3L1 might be related to the development of milder forms of asthma.
Increased serum YKL-40 was related with poor collateral development and high SYNTAX score in patients with coronary artery disease.
Plasma YKL-40 and IL-6 (show IL6 ELISA Kits) had less diagnostic impact than CA 19.9
Findings show high level of both YKL-40 and GAP-43 (show GAP43 ELISA Kits) in CSF (show CSF2 ELISA Kits) of older women with suicidal ideation which suggest that a disrupted synaptic glial functioning and inflammation may be related to the aetiology of suicidal ideation in older adults.
fibroblast-derived Chi3L1 as a novel key player in the complex reciprocal interactions of stromal cells that facilitate tumor progression and metastasis.
Findings suggest that elevated serum YKL-40 levels are associated with the existence of uterine leiomyomas, and YKL-40 might be a potential adjunct biomarker for diagnosis of uterine leiomyomas.
Collagen binds in two locations at the YKL-40 surface, potentially related to a role in fibrillar formation. Finally, heparin non-specifically binds at the YKL-40 surface, as predicted from structural studies
This is the first report on the association between low-frequency and common variants in the chitinases-related genes CHIA and CHI3L1 with the intensity of specific IgE to ABA-1 in a population naturally exposed to Ascaris and with Bet v 1 in a Swedish population.
results indicate that patients with CHI3L1 rs880633 variant genotypes TC+CC are at a higher risk of HCC (show FAM126A ELISA Kits). CHI3L1 polymorphisms rs880633 or rs4950928 may be potential candidates for predicting poor HCC (show FAM126A ELISA Kits) prognosis and clinical status.
High YKL-40 levels were associated with a 2-fold increased risk of venous thromboembolism, but the association was not causal.
chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
, cartilage glycoprotein 39
, chitinase-3-like protein 1
, 39 kDa synovial protein
, 38 kDa heparin-binding glycoprotein
, signal-processing protein
, 39 kDa whey protein
, 40 kDa secretory signalling glycoprotein
, cartilage glycoprotein-39
, chitinase-like protein 1
, signal processing protein
, chitinase 3-like 1 protein
, mammary gland protein 40