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Chloride Channel 2 (CLCN2) ELISA Kits

CLCN2 encodes a voltage-gated chloride channel. Additionally we are shipping Chloride Channel 2 Antibodies (55) and Chloride Channel 2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse CLCN2 CLCN2 12724 Q9R0A1
Anti-Human CLCN2 CLCN2 1181 P51788
Anti-Rat CLCN2 CLCN2 29232 P35525
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More ELISA Kits for Chloride Channel 2 Interaction Partners

Zebrafish Chloride Channel 2 (CLCN2) interaction partners

  1. Identification and characterization of the zebrafish ClC (show CLCF1 ELISA Kits)-2a/b/c chloride channel (show CLCA1 ELISA Kits) orthologs.

Mouse (Murine) Chloride Channel 2 (CLCN2) interaction partners

  1. Genetic ablation of ClC-2 resulted in reduced gastric gland region, reduced parietal cell number, reduced H/K ATPase (show ATP4b ELISA Kits), reduced tubulovesicles and reduced stimulated acid secretion.

  2. Data indicate that membrane protein MLC1 is crucial for proper localization of adhesion molecule (show NCAM1 ELISA Kits) GlialCAM (show HEPACAM ELISA Kits) and chloride channel (show CLCA1 ELISA Kits) ClC-2, and for changing ClC-2 currents.

  3. Loss of ClC-2 is associated with increased development of DSS (show PMP22 ELISA Kits)-induced colitis.

  4. The PCR data revealed the existence of two astrocytic subpopulations markedly differing in their gene expression levels for inwardly rectifying K+ channels (Kir4.1 (show KCNJ10 ELISA Kits)), K(2P) channels (TREK-1 (show KCNK2 ELISA Kits) and TWIK-1 (show KCNK1 ELISA Kits)) and Cl- channels (ClC2).

  5. ClC-2 channels are required for colonic electroneutral absorption of NaCl and KCl.

  6. permeant Cl(-) ions contribute to V(m)-dependent gating of the broadly distributed ClC-2 Cl() channel.

  7. GABAA (show GABRg1 ELISA Kits) receptor-mediated synaptic inputs from basket cells were modulated by ClC-2. Our data reveal a previously unknown cell type-specific regulation of intracellular chloride homeostasis in the perisomatic region of hippocampal pyramidal neurons.

  8. ClC-2 reduces barrier function in normal mucosa. Ultrastructural morphology of tight junctions and myosin light chain kinase (show MYLK ELISA Kits) appear to be important to the function of ClC-2 in normal mucosa.

  9. these findings raise the possibility that ClC-2 expression plays a subtle neuroprotective role in the aging hippocampus

  10. Heterozygous nmf240 mice present with a reduced electroretinography light peak component suggests that CLCN2 is necessary for the generation of this response component.

Pig (Porcine) Chloride Channel 2 (CLCN2) interaction partners

  1. ClC-2-mediated intestinal Cl - secretion restores transepithelial resistance in ischemia-injured intestine.

Human Chloride Channel 2 (CLCN2) interaction partners

  1. Hyperpolarization activates CLC-2 mainly by driving intracellular anions into the channel pores.

  2. The extracellular domain of GlialCAM (show HEPACAM ELISA Kits) is necessary for cell junction targeting and for mediating interactions with itself or with MLC1 and ClC-2.

  3. both ubiquitous (AP-1A) and epithelium-specific (AP-1B) forms of the tetrameric clathrin adaptor AP-1 (show FOSB ELISA Kits) are capable of carrying out basolateral sorting of ClC-2.

  4. SPAK (show STK39 ELISA Kits) and OSR1 (show OXSR1 ELISA Kits) are powerful negative regulators of the cell volume regulatory Cl- channel ClC-2

  5. Correlation between CLC-2 gene expression and the cytoskeleton in human trabecular meshwork cells.

  6. Our observations substantiate the concept that ClC-2 is involved in brain ion and water homoeostasis

  7. JAK2 (show JAK2 ELISA Kits) down-regulates ClC-2 activity and thus counteracts Cl(-) exit, an effect which may impact on cell volume regulation

  8. This study demonistrated that the first auxiliary subunit of ClC-2 and suggests that ClC-2 may play a role in the pathology of MLC disease.

  9. ClC-2 plays an important role in the modulation of tight junctions by influencing caveolar trafficking of tight junction protein occludin (show OCLN ELISA Kits).

  10. Sequence analysis of CLCN2 at genomic DNA and cDNA levels in 18 megalencephalic leukoencephalopathy MLC1 mutations revealed some nucleotide changes, but they were predicted to be nonpathogenic.

Chloride Channel 2 (CLCN2) Antigen Profile

Antigen Summary

This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Chloride Channel 2 (CLCN2) ELISA Kits

  • chloride channel 2 (CLCN2) antibody
  • novel protein similar to vertebrate chloride channel 2 (CLCN2) (CH211-117K11.1) antibody
  • chloride channel protein 2 (EHI_142170) antibody
  • chloride channel protein 2 (EHI_186860) antibody
  • chloride channel 2 (Clcn2) antibody
  • chloride channel protein 2 variant (CLC-2) antibody
  • chloride channel, voltage-sensitive 2 (CLCN2) antibody
  • chloride channel, voltage-sensitive 2 (Clcn2) antibody
  • AL118368 antibody
  • CIC-2 antibody
  • clC-2 antibody
  • Clc2 antibody
  • CLCN2 antibody
  • ECA2 antibody
  • ECA3 antibody
  • EGI3 antibody
  • EGI11 antibody
  • EGMA antibody
  • EJM6 antibody
  • EJM8 antibody
  • LOC100150892 antibody
  • nmf240 antibody

Protein level used designations for Chloride Channel 2 (CLCN2) ELISA Kits

chloride channel 2 , novel protein similar to vertebrate chloride channel 2 (CLCN2) , chloride channel protein 2 , PKA-activated chloride channel ClC-2G , clC-2

704709 Macaca mulatta
100125625 Ovis aries
100150892 Danio rerio
3405494 Entamoeba histolytica HM-1:IMSS
3410767 Entamoeba histolytica HM-1:IMSS
12724 Mus musculus
505569 Bos taurus
100135500 Cavia porcellus
397147 Sus scrofa
1181 Homo sapiens
29232 Rattus norvegicus
488106 Canis lupus familiaris
100009530 Oryctolagus cuniculus
425295 Gallus gallus
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