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anti-Chloride Channel Ka (CLCNKA) Antibodies

CLCNKA is a member of the CLC family of voltage-gated chloride channels. Additionally we are shipping Chloride Channel Ka Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLCNKA 12733 Q9WUB7
CLCNKA 1187 P51800
CLCNKA 79425 Q06393
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Top anti-Chloride Channel Ka Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB CLCNKA Antibody (N-term)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CLCNKA antibody detected the CLCNKA protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of CLCNKA expression in HeLa (A), rat liver (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details

CLCNKA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human ,


, , , , ,
Rat (Rattus)


Top referenced anti-Chloride Channel Ka Antibodies

  1. Human Polyclonal CLCNKA Primary Antibody for ELISA, WB - ABIN1451160 : Estévez, Boettger, Stein, Birkenhäger, Otto, Hildebrandt, Jentsch: Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion. in Nature 2001 (PubMed)
    Show all 2 references for ABIN1451160

  2. Human Polyclonal CLCNKA Primary Antibody for WB - ABIN2776159 : Krämer, Bergler, Stoelcker, Waldegger: Mechanisms of Disease: the kidney-specific chloride channels ClCKA and ClCKB, the Barttin subunit, and their clinical relevance. in Nature clinical practice. Nephrology 2007 (PubMed)

More Antibodies against Chloride Channel Ka Interaction Partners

Mouse (Murine) Chloride Channel Ka (CLCNKA) interaction partners

  1. molecular substrate of a chloride channel (show CLCA1 Antibodies) previously detected in the mouse thick ascending limb

  2. the major component of Cl(-) transport sensitive to NPPB (show BNP Antibodies) or pH is mediated by CLC-K1 in the tAL (show TALDO1 Antibodies).

  3. Gene expression profiling in the collecting tubules of aquaporin-1 (show AQP1 Antibodies) and CLC (show CLC Antibodies)-Nk1 (show HGF Antibodies) knockout mice.

  4. induction of SGK1 (show SGK1 Antibodies), CLC-K1 and barttin (show BSND Antibodies) by high osmolarity and change in intracellular volume in distal renal tubular cells in vivo and in vitro

Human Chloride Channel Ka (CLCNKA) interaction partners

  1. Single loci of tag Single Nucleotide Polymorphisms of CLCNKA_B are not enough to increase the Essential Hypertension susceptibility, the combination of CLCNKA SNP, salt, marine products, meat, edible oil consumption is associated with elevated risk.

  2. R8W and G47R, two naturally occurring barttin (show BSND Antibodies) mutations identified in patients with Bartter syndrome type IV, reduce barttin (show BSND Antibodies) palmitoylation and CLC-K (show CLCNKB Antibodies)/barttin (show BSND Antibodies) channel activity.

  3. HEK293 cells the potentiating effect of niflumic acid (NFA) on CLC-Ka (show CLCNKB Antibodies)/barttin (show BSND Antibodies) and CLC-Kb (show CLCNKB Antibodies)/barttin (show BSND Antibodies) channels seems to be absent while the blocking efficacy of niflumic acid and benzofuran derivatives observed in oocytes is preserved

  4. following variables were significantly associated with an estimated glomerular filtration rate: age, type 2 diabetes, total cholesterol, LDL-cholesterol, and the CLCNKA GG genotype

  5. The variant CLCNKA risk allele, telegraphed by linked variants in the adjacent HSPB7 (show HSPB7 Antibodies) gene, uncovers a previously overlooked genetic mechanism affecting the cardio-renal axis.

  6. Identify a protein region that is involved in calcium binding and that is likely undergoing conformational changes underlying the complex gating of CLC-K (show CLCNKB Antibodies) channels.

  7. Combined impairment of ClC-Ka (show CLCNKB Antibodies) and ClC-Kb (show CLCNKB Antibodies) results in phenotype that mimics neonatal Barrter's syndrome with deafness

  8. Barttin (show BSND Antibodies) modulates trafficking and function of ClC-K1 and ClC-Kb (show CLCNKB Antibodies) channels

  9. CLCNKA genetic variants may have roles in salt-sensitive hypertension

  10. The structure of the cytoplasmic domain of CLCNKA reveals a conserved interaction interface.

Chloride Channel Ka (CLCNKA) Antigen Profile

Protein Summary

This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CLCNKA

  • chloride channel Ka (CLCNKA) antibody
  • chloride channel Ka (Clcnka) antibody
  • chloride channel, voltage-sensitive Ka (CLCNKA) antibody
  • chloride channel, voltage-sensitive Ka (Clcnka) antibody
  • C75963 antibody
  • ClC-K1 antibody
  • CLCK1 antibody
  • Clcnk1 antibody
  • CLCNKA antibody
  • CLCNKB antibody
  • hClC-Ka antibody

Protein level used designations for CLCNKA

chloride channel Ka , chloride channel protein ClC-Ka-like , chloride channel K1 , chloride channel protein ClC-Ka , putative basolateral cTAL chloride channel ClC-Ka , chloride channel, kidney, A , clC-K1 , Chloride channel protein ClC-Kb , chloride channel Kb , clC-K2

GENE ID SPECIES
469844 Pan troglodytes
703259 Macaca mulatta
100456543 Pongo abelii
100593875 Nomascus leucogenys
12733 Mus musculus
1187 Homo sapiens
79425 Rattus norvegicus
100009213 Oryctolagus cuniculus
Selected quality suppliers for anti-Chloride Channel Ka (CLCNKA) Antibodies
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