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anti-Chloride Channel Kb (CLCNKB) Antibodies

The protein encoded by CLCNKB is a member of the family of voltage-gated chloride channels. Additionally we are shipping CLCNKB Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLCNKB 56365 Q9WUB6
CLCNKB 1188 P51801
CLCNKB 79430 P51802
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Top anti-CLCNKB Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CLCNKB Antibody Titration: 0.2-1 ug/mlELISA Titer: 1... WB Suggested Anti-CLCNKB  Antibody Titration: 0.2-1 µg/mL ELISA Titer:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB CLCNKB Antibody (N-term) western blot analysis in mouse kidney tissue ... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB CLCNKB Antibody (N-term)  western blot analysis in mouse kidney tissue... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

CLCNKB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,

Human , , , ,

Rat (Rattus) , , ,

Top referenced anti-CLCNKB Antibodies

  1. Human Polyclonal CLCNKB Primary Antibody for EIA, WB - ABIN951557 : Yu, Xu, Pan, Ren, Wang, Meng, Huang, Chen: Identification and functional analysis of novel mutations of the CLCNKB gene in Chinese patients with classic Bartter syndrome. in Clinical genetics 2010 (PubMed)
    Show all 4 references for ABIN951557

  2. Cow (Bovine) Polyclonal CLCNKB Primary Antibody for WB - ABIN2776083 : Gorgojo, Donnay, Jeck, Konrad: A Spanish founder mutation in the chloride channel gene, CLCNKB, as a cause of atypical Bartter syndrome in adult age. in Hormone research 2006 (PubMed)

  3. Cow (Bovine) Polyclonal CLCNKB Primary Antibody for WB - ABIN2776082 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

More Antibodies against CLCNKB Interaction Partners

Mouse (Murine) Chloride Channel Kb (CLCNKB) interaction partners

  1. IGF-1 (show IGF1 Antibodies), by stimulating ClC-K2 channels, promotes net Na(+) and Cl(-) reabsorption, thus reducing driving force for potassium secretion by the cortical collecting duct.

Human Chloride Channel Kb (CLCNKB) interaction partners

  1. Single loci of tag Single Nucleotide Polymorphisms of CLCNKA_B are not enough to increase the Essential Hypertension susceptibility, the combination of CLCNKA (show CLCNKA Antibodies) SNP, salt, marine products, meat, edible oil consumption is associated with elevated risk

  2. results demonstrate that the carboxyl terminus of hClC-Kb is not part of the binding site for barttin (show BSND Antibodies), but functionally modifies the interplay with barttin (show BSND Antibodies).

  3. These results demonstrate that mutations in a cluster of hydrophobic residues within transmembrane domain 1 affect barttin (show BSND Antibodies)-CLC-K interaction and impair gating modification by the accessory subunit

  4. we report here for the first time that ClC-Kb disease-causing mutations located around the selectivity filter can result in both reduced surface expression and hyperactivity in heterologous expression systems

  5. Case Report: 2 mutations in the CLCNKB gene, leading to a molecular diagnosis of Bartter syndrome type III in case of sudden infant death.

  6. R8W and G47R, two naturally occurring barttin (show BSND Antibodies) mutations identified in patients with Bartter syndrome type IV, reduce barttin (show BSND Antibodies) palmitoylation and CLC-K/barttin (show BSND Antibodies) channel activity.

  7. HEK293 cells the potentiating effect of niflumic acid (NFA) on CLC-Ka/barttin (show BSND Antibodies) and CLC-Kb/barttin (show BSND Antibodies) channels seems to be absent while the blocking efficacy of niflumic acid and benzofuran derivatives observed in oocytes is preserved

  8. study investigated the functional consequences of seven mutations; four mutants carried no current whereas others displayed a 30-60 percent reduction in conductance as compared with wild-type ClC-Kb

  9. expands the association between CLCNKB and essential hypertension to a non-European ancestry population

  10. This article presents the case of a patient with hypokalaemia caused by CLCNKB gene mutation hard to categorise as GS or BS type 3.

Xenopus laevis Chloride Channel Kb (CLCNKB) interaction partners

  1. The open probability and mean open time of ClC-2 (show CLCN2 Antibodies) was voltage dependent, decreasing dramatically as the patches were depolarized. ClC-2 (show CLCN2 Antibodies) is uniquely suitable to promote anion secretion with little anion reabsorption.

CLCNKB Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CLCNKB

  • chloride channel, voltage-sensitive Kb (CLCNKB) antibody
  • similar to chloride channel (putative) (CLCNKB) antibody
  • chloride channel Kb (CLCNKB) antibody
  • chloride channel K (clcnk) antibody
  • chloride channel Ka (CLCNKA) antibody
  • chloride channel Kb (Clcnkb) antibody
  • chloride channel, voltage-sensitive Ka (CLCNKA) antibody
  • chloride channel, voltage-sensitive Kb (Clcnkb) antibody
  • chloride channel, voltage-sensitive Kb (clcnkb) antibody
  • ClC-k antibody
  • ClC-K2 antibody
  • ClC-K2L antibody
  • Clc-Ka antibody
  • clc-kb antibody
  • Clck2 antibody
  • clckb antibody
  • Clcnk1l antibody
  • CLCNKA antibody
  • clcnka-A antibody
  • CLCNKB antibody
  • clk-k2 antibody
  • DKFZp469N0132 antibody
  • x6clck antibody
  • xCIC-K antibody
  • xClC-K antibody
  • zgc:64141 antibody

Protein level used designations for CLCNKB

chloride channel Kb , chloride channel Ka , CIC-K , chloride channel protein ClC-Kb-like , chloride channel K1-like; putative basolateral cTAL chloride channel ClC-Ka , chloride channel protein ClC-Kb , clC-K2 , putative basolateral mTAL chloride channel ClC-Ka , Chloride channel protein ClC-Kb , chloride channel protein ClC-Ka , clC-K1 , chloride channel, kidney, B , chloride channel K2

GENE ID SPECIES
703476 Macaca mulatta
428190 Gallus gallus
456470 Pan troglodytes
100171573 Pongo abelii
393353 Danio rerio
100017912 Monodelphis domestica
100400180 Callithrix jacchus
100590605 Nomascus leucogenys
538145 Bos taurus
56365 Mus musculus
100009213 Oryctolagus cuniculus
1188 Homo sapiens
487422 Canis lupus familiaris
79430 Rattus norvegicus
378616 Xenopus laevis
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