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anti-Choline Kinase alpha (CHKA) Antibodies

The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Additionally we are shipping Choline Kinase alpha Kits (5) and Choline Kinase alpha Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHKA 1119 P35790
CHKA 12660 O54804
CHKA 29194 Q01134
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Top anti-Choline Kinase alpha Antibodies at

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-CHKA Antibody Titration: 0.2-1 ug/mlPositive Control: Human Liver 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB Western blot analysis of anti-CHK (ABIN392815) in HepG2 cell line lysate (35 µg/lane).CHK(arrow) was detected using the purified polyclonal antibody (1:40 dilution). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated EIA, WB The anti-CHK Pab is used in Western blot to detect CHK in mouse heart tissue lysate. 0.4 mL Log in to see 6 to 8 Days
Human Mouse Un-conjugated ELISA, WB CHKA polyclonal antibody (A01), Lot # GPC1060208QCS1 Western Blot analysis of CHKA expression in A-431 . Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
Yeast Rabbit Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Choline kinase alpha Antibody [NBP1-85630] - Staining of human bronchus shows strong cytoplasmic positivity in mucous respiratory epithelial cells. Western Blot: Choline kinase alpha Antibody [NBP1-85630] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403943) 0.1 mL Log in to see 8 to 11 Days

CHKA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,

, , , , ,
Mouse (Murine)

Rat (Rattus)

Top referenced anti-Choline Kinase alpha Antibodies

  1. Chicken Polyclonal Choline Kinase alpha Primary Antibody for WB - ABIN2785459 : Glunde, Shah, Winnard, Raman, Takagi, Vesuna, Artemov, Bhujwalla: Hypoxia regulates choline kinase expression through hypoxia-inducible factor-1 alpha signaling in a human prostate cancer model. in Cancer research 2008 (PubMed)

  2. Human Polyclonal Choline Kinase alpha Primary Antibody for ELISA, WB - ABIN560360 : Vanpouille, Le Jeune, Kryza, Clotagatide, Janier, Dubois, Perek: Influence of multidrug resistance on (18)F-FCH cellular uptake in a glioblastoma model. in European journal of nuclear medicine and molecular imaging 2009 (PubMed)

More Antibodies against Choline Kinase alpha Interaction Partners

Human Choline Kinase alpha (CHKA) interaction partners

  1. Study shows increased CHKA expression in pancreatic ductal adenocarcinoma tumors and may be a predictive marker of response to chemotherapy.

  2. These data also support the approach of antitumor strategies that destabilize Chk-alpha protein or downregulate PtdCho in breast cancer treatment.

  3. Downregulation of choline kinase-alpha enhances autophagy in tamoxifen-resistant breast cancer cells.

  4. CHKA can act as an AR chaperone, providing, to our knowledge, the first evidence for kinases as molecular chaperones, making CHKA both a marker of tumor progression and a potential therapeutic target for PCa (show FLVCR1 Antibodies).

  5. Identify choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma.

  6. choline kinase alpha is inhibited by a near-infrared fluorescent carbocyanine

  7. Increased expression of CHKA is seen in malignant lesions of prostate cancer

  8. Chokalpha possessed oncogenic activity and could be a potential therapeutic target in T-cell lymphoma , as well as other hematological malignancies with interrupted Ras signaling pathways

  9. Downregulation of Chk-alpha with siRNA increased PLD1 expression, and downregulation of PLD1 increased Chk-alpha expression.

  10. The significance of CHKA overexpression on a TMA.

Mouse (Murine) Choline Kinase alpha (CHKA) interaction partners

  1. hepatic phosphatidylcholine (show SGMS2 Antibodies) is regulated by the circadian clock through a Bmal1 (show ARNTL Antibodies)-Rev-erbalpha (show NR1D1 Antibodies)-Chkalpha axis

  2. Enforced expression of either CK(alpha) or CCTalpha (show PCYT1A Antibodies) increased the rate of synthesis and the amount of PtdCho, and these cells initiated neuronal differentiation.

  3. Lack of muscle degeneration in forelimbs of Chkb (show CHKB Antibodies)(-/-) mice is due to abundant choline kinase alpha and the stable homeostasis of phosphatidylcholine (show SGMS2 Antibodies).

  4. Experimental evidence for the presence of heteromeric ChoK/EtnK in any source. The activity of ChoK/EtnK in the cell is controlled not only by the level of each isoform but also by their combination to form the active oligomer complex.

  5. ChoK may have a role in carcinogenesis

  6. Data suggest that the choline kinase alpha promoter has a distal element (-875/-867) that binds c-jun (show JUN Antibodies) and the binding of c-jun (show JUN Antibodies) is enhanced by treatment with CCl4 (show CCL4 Antibodies).

  7. Chka is an essential gene for early embryonic development, but adult mice do not require full expression of the gene for normal levels of phosphatidylcholine (show SGMS2 Antibodies).

Choline Kinase alpha (CHKA) Antigen Profile

Protein Summary

The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CHKA

  • choline kinase alpha (chka) antibody
  • choline kinase alpha (CHKA) antibody
  • choline kinase alpha (MCYG_00090) antibody
  • choline kinase (PF14_0020) antibody
  • choline kinase 1 (CK1) antibody
  • choline kinase (CNI01400) antibody
  • choline kinase alpha (Chka) antibody
  • ATCK1 antibody
  • Chetk-alpha antibody
  • Chk antibody
  • CHKA antibody
  • chkb antibody
  • ChoK antibody
  • CHOLINE KINASE antibody
  • choline kinase 1 antibody
  • CK antibody
  • CK-R antibody
  • CK/EK-alpha antibody
  • CKI antibody
  • EK antibody
  • EtnK-alpha antibody
  • F14O23.8 antibody
  • F14O23_8 antibody
  • im:7143625 antibody
  • si:dkey-12e7.3 antibody
  • wu:fd46h01 antibody

Protein level used designations for CHKA

choline kinase alpha , choline kinase beta , choline kinase , CHETK-alpha , ethanolamine kinase , choline/ethanolamine kinase alpha , CK , EK , choline kinase R

558499 Danio rerio
476002 Canis lupus familiaris
514865 Bos taurus
451376 Pan troglodytes
496957 Xenopus (Silurana) tropicalis
9223440 Arthroderma otae CBS 113480
811591 Plasmodium falciparum 3D7
843500 Arabidopsis thaliana
3259492 Cryptococcus neoformans var. neoformans JEC21
100013074 Monodelphis domestica
100059839 Equus caballus
100566078 Anolis carolinensis
100587988 Nomascus leucogenys
423112 Gallus gallus
1119 Homo sapiens
12660 Mus musculus
29194 Rattus norvegicus
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