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G-protein coupled receptor, muscarinic receeptor subtype that mediates cholinergic-induced contraction in most smooth muscle [RGD, Feb 2006].. Additionally we are shipping CHRM3 Kits (28) and CHRM3 Proteins (6) and many more products for this protein.
Showing 10 out of 66 products:
Human Polyclonal CHRM3 Primary Antibody for WB - ABIN1742046
Frucht, Jensen, Dexter, Yang, Xiao: Human colon cancer cell proliferation mediated by the M3 muscarinic cholinergic receptor. in Clinical cancer research : an official journal of the American Association for Cancer Research 1999
Show all 3 references for ABIN1742046
Mouse (Murine) Polyclonal CHRM3 Primary Antibody for IF (p), IHC (p) - ABIN674484
Chen, Li, Zhang, Zhai, Gong, Qiang, Xue: An ENU-induced mutation of Nrg1 causes dilated pupils and a reduction in muscarinic receptors in the sphincter pupillae. in PLoS ONE 2011
Show all 3 references for ABIN674484
Human Polyclonal CHRM3 Primary Antibody for ELISA, WB - ABIN560365
Cheng, Cao, Zheng, Wang, Sun, Liu, Zhang, Wang, Zhu, Wu: Airway hyperresponsiveness induced by repeated esophageal infusion of HCl in guinea pigs. in American journal of respiratory cell and molecular biology 2014
Show all 2 references for ABIN560365
To our knowledge, this is the first genetic association study that reveals the genetic contribution of CHRM3 gene in bladder cancer etiology.
The CHRM3 gene plays a role in abnormal thalamo-orbital frontal cortex functional connectivity in first-episode treatment-naive patients with schizophrenia.
These findings indicate that M3 mAChR may be important therapeutic target for obstructive airway diseases, as it regulates the effects of the epithelial-derived chemokines on ASM (show SMPD1 Antibodies) cell migration, which results in lung remodeling.
Blockading CHRM3 by shRNA or treatment with darifenacin inhibited prostate cancer growth.
results suggest that the autoantibodies against peptides of the second extracellular loop of M3R (show CHRM4 Antibodies) are not pathogenic in vivo and they are not suitable as biomarkers for pSS (show CDSN Antibodies) diagnosis
Report using biosensing techniques to monitor dynamic changes of inositol lipid pools in living cells reveals a PKC (show PRRT2 Antibodies)-dependent PtdIns4P increase upon EGF (show EGF Antibodies) and M3 receptor activation.
M3 AChR or AMP-activated protein kinase (show PRKAA2 Antibodies) Small Interfering RNA abrogated the ACh (show FGFR3 Antibodies)-elicited the attenuation of Endoplasmic reticulum stress in endothelial cells, indicating that the salutary effects of ACh (show FGFR3 Antibodies) were likely mediated by M3 AChR-AMPK (show PRKAA1 Antibodies) signaling.
Suggest Gbeta4gamma1 as a modulator of M3 muscarinic receptor signaling.
Cigarette smoking may contribute to this imbalance by affecting the polarization and survival of Th/Tregs through the up-regulation of MR3 and MR5.
ACh (show FGFR3 Antibodies)-induced activation of EGFR (show EGFR Antibodies)/PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) pathway and subsequent IL-8 (show IL8 Antibodies) upregulation may be one of the important mechanisms of M3R (show CHRM4 Antibodies) function
Data suggest that both M(2) and M(3) muscarinic receptors mediate the contraction in both pig clasp (show CLASRP Antibodies) and sling fibers similar to human clasp (show CLASRP Antibodies) and sling fibers.
Sequential activation of muscarinic M3 receptors and cannabinoid CB1 (show CNR1 Antibodies) receptors produce synergistic contractile effects of the bovine ciliary muscle by involving the activation of Rho-kinase (show ROCK1 Antibodies) and protein kinase C (show PKC Antibodies).
These data support the existence of a novel transducing cascade, involving Galpha (show SUCLG1 Antibodies)(q16)beta gamma coupling M(3)AChR to NPR (show NPTXR Antibodies)-GC.
airway M(2)Rs inhibit BK channels by a dual, Gbetagamma-mediated mechanism, a direct membrane-delimited interaction, and the activation of the phospholipase C (show PLC Antibodies)/protein (show HNRNPC Antibodies) kinase C (show PKC Antibodies) pathway
Arthritis-induced joint destruction was significantly stronger in mice with M3 muscarinic acetylcholine receptor deficiency.
The effects of muscarinic receptor (show CHRM5 Antibodies) M3 knockout on cathepsin K (show CTSK Antibodies) expression, bone density and biomechanical properties of bone are reported.
results suggest that the autoantibodies against peptides of the second extracellular loop of M3R are not pathogenic in vivo and they are not suitable as biomarkers for pSS (show CDSN Antibodies) diagnosis
Expression of the M3 receptors mediating cholinergic contractile stimuli of the detrusor muscle was dysregulated in both Mras (show MRAS Antibodies)-/- males and females, although only males exhibited a urinary phenotype.
The study screened CrkL (show CRKL Antibodies) binding proteins using RNA interference (RNAi) and identified Sorbs1 (show SORBS1 Antibodies) and Sorbs2 (show Sorbs2 Antibodies) as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro.
Activation of Chrm3 inhibits the recruitment of beta-arrestin-2 (show ARRB2 Antibodies) to odorant receptors, resulting in a potentiation of odor-induced responses in olfactory sensory neurons.
The muscarinic M3R receptor interacts directly with NOSTRIN (show NOSTRIN Antibodies) at the plasma membrane in the aorta.
Cholinergic signalling via the M3R is essential for optimal Th1 (show HAND1 Antibodies) and Th2 adaptive immunity to infection.
Our results identify a novel candidate mouse gene, Zfp277, whose expression pattern is compatible with a role in mediating divergent effects of Chrm3 and Chrm1 (show CHRM1 Antibodies) gene ablation on murine intestinal neoplasia.
In this review, genetic modifications of muscarinic M3 receptor cause robust alterations in insulin (show INS Antibodies) levels and glucose tolerance.
G-protein coupled receptor, muscarinic receeptor subtype that mediates cholinergic-induced contraction in most smooth muscle
m3 muscarinic acetylcholine receptor
, muscarinic acetylcholine receptor M3
, cholinergic receptor, muscarinic 3
, acetylcholine receptor, muscarinic 3
, m3 muscarinic receptor
, cholinergic receptor, muscarinic 3, cardiac
, M3 muscarinic acetylcholine receptor
, AChR M3
, mm3 mAChR
, muscarinic acetylcholine receptor 3