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Cholinergic Receptor, Muscarinic 3 Proteins (CHRM3)

G-protein coupled receptor, muscarinic receeptor subtype that mediates cholinergic-induced contraction in most smooth muscle [RGD, Feb 2006].. Additionally we are shipping CHRM3 Antibodies (65) and CHRM3 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHRM3 1131 P20309
Rat CHRM3 CHRM3 24260 P08483
CHRM3 12671 Q9ERZ3
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Top CHRM3 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details

CHRM3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
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More Proteins for Cholinergic Receptor, Muscarinic 3 (CHRM3) Interaction Partners

Human Cholinergic Receptor, Muscarinic 3 (CHRM3) interaction partners

  1. Blockading CHRM3 by shRNA or treatment with darifenacin inhibited prostate cancer growth.

  2. results suggest that the autoantibodies against peptides of the second extracellular loop of M3R (show CHRM4 Proteins) are not pathogenic in vivo and they are not suitable as biomarkers for pSS (show CDSN Proteins) diagnosis

  3. Report using biosensing techniques to monitor dynamic changes of inositol lipid pools in living cells reveals a PKC (show PRRT2 Proteins)-dependent PtdIns4P increase upon EGF (show EGF Proteins) and M3 receptor activation.

  4. M3 AChR or AMP-activated protein kinase (show PRKAA2 Proteins) Small Interfering RNA abrogated the ACh (show FGFR3 Proteins)-elicited the attenuation of Endoplasmic reticulum stress in endothelial cells, indicating that the salutary effects of ACh (show FGFR3 Proteins) were likely mediated by M3 AChR-AMPK (show PRKAA1 Proteins) signaling.

  5. Suggest Gbeta4gamma1 as a modulator of M3 muscarinic receptor signaling.

  6. Cigarette smoking may contribute to this imbalance by affecting the polarization and survival of Th/Tregs through the up-regulation of MR3 and MR5.

  7. ACh (show FGFR3 Proteins)-induced activation of EGFR (show EGFR Proteins)/PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) pathway and subsequent IL-8 (show IL8 Proteins) upregulation may be one of the important mechanisms of M3R (show CHRM4 Proteins) function

  8. M3R (show CHRM4 Proteins) preserves the endothelial barrier function through a mechanism potentially maintaining PTP1B (show PTPN1 Proteins) activity, keeping the adherens junction proteins (AJPs) dephosphorylation.

  9. Results uncovered that Gaq (show GNAQ Proteins) binding to GRK2 (show ADRBK1 Proteins) enhances the recruitment of GRK2 (show ADRBK1 Proteins) to M3-ACh (show FGFR3 Proteins) receptors.

  10. HM3-mediated IL8 expression through PKC-NFkappaB signaling pathways

Pig (Porcine) Cholinergic Receptor, Muscarinic 3 (CHRM3) interaction partners

  1. Data suggest that both M(2) and M(3) muscarinic receptors mediate the contraction in both pig clasp (show CLASRP Proteins) and sling fibers similar to human clasp (show CLASRP Proteins) and sling fibers.

Cow (Bovine) Cholinergic Receptor, Muscarinic 3 (CHRM3) interaction partners

  1. Sequential activation of muscarinic M3 receptors and cannabinoid CB1 receptors produce synergistic contractile effects of the bovine ciliary muscle by involving the activation of Rho-kinase and protein kinase C.

  2. These data support the existence of a novel transducing cascade, involving Galpha (show SUCLG1 Proteins)(q16)beta gamma coupling M(3)AChR to NPR (show NPTXR Proteins)-GC.

  3. airway M(2)Rs inhibit BK channels by a dual, Gbetagamma-mediated mechanism, a direct membrane-delimited interaction, and the activation of the phospholipase C/protein kinase C pathway

Mouse (Murine) Cholinergic Receptor, Muscarinic 3 (CHRM3) interaction partners

  1. Arthritis-induced joint destruction was significantly stronger in mice with M3 muscarinic acetylcholine receptor deficiency.

  2. The effects of muscarinic receptor (show CHRM5 Proteins) M3 knockout on cathepsin K (show CTSK Proteins) expression, bone density and biomechanical properties of bone are reported.

  3. results suggest that the autoantibodies against peptides of the second extracellular loop of M3R are not pathogenic in vivo and they are not suitable as biomarkers for pSS (show CDSN Proteins) diagnosis

  4. Expression of the M3 receptors mediating cholinergic contractile stimuli of the detrusor muscle was dysregulated in both Mras (show MRAS Proteins)-/- males and females, although only males exhibited a urinary phenotype.

  5. The study screened CrkL (show CRKL Proteins) binding proteins using RNA interference (RNAi) and identified Sorbs1 (show SORBS1 Proteins) and Sorbs2 (show Sorbs2 Proteins) as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro.

  6. Activation of Chrm3 inhibits the recruitment of beta-arrestin-2 (show ARRB2 Proteins) to odorant receptors, resulting in a potentiation of odor-induced responses in olfactory sensory neurons.

  7. The muscarinic M3R receptor interacts directly with NOSTRIN (show NOSTRIN Proteins) at the plasma membrane in the aorta.

  8. Cholinergic signalling via the M3R is essential for optimal Th1 (show HAND1 Proteins) and Th2 adaptive immunity to infection.

  9. Our results identify a novel candidate mouse gene, Zfp277, whose expression pattern is compatible with a role in mediating divergent effects of Chrm3 and Chrm1 (show CHRM1 Proteins) gene ablation on murine intestinal neoplasia.

  10. In this review, genetic modifications of muscarinic M3 receptor cause robust alterations in insulin (show INS Proteins) levels and glucose tolerance.

CHRM3 Protein Profile

Protein Summary

G-protein coupled receptor, muscarinic receeptor subtype that mediates cholinergic-induced contraction in most smooth muscle

Gene names and symbols associated with CHRM3

  • cholinergic receptor, muscarinic 3 (CHRM3)
  • cholinergic receptor, muscarinic 3 (LOC100218380)
  • cholinergic receptor, muscarinic 3 (LOC100355313)
  • cholinergic receptor, muscarinic 3 (Chrm3)
  • cholinergic receptor, muscarinic 3, cardiac (Chrm3)
  • Chrm-3 protein
  • EGBRS protein
  • HM3 protein
  • M3 protein
  • M3R protein
  • MACHR protein

Protein level used designations for CHRM3

m3 muscarinic acetylcholine receptor , muscarinic acetylcholine receptor M3 , cholinergic receptor, muscarinic 3 , acetylcholine receptor, muscarinic 3 , m3 muscarinic receptor , cholinergic receptor, muscarinic 3, cardiac , M3 muscarinic acetylcholine receptor , AChR M3 , mm3 mAChR , muscarinic acetylcholine receptor 3

GENE ID SPECIES
403827 Canis lupus familiaris
708901 Macaca mulatta
100218380 Taeniopygia guttata
100355313 Oryctolagus cuniculus
100597211 Nomascus leucogenys
1131 Homo sapiens
24260 Rattus norvegicus
100144478 Sus scrofa
281685 Bos taurus
396364 Gallus gallus
100172838 Pongo abelii
469725 Pan troglodytes
12671 Mus musculus
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