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anti-Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) Antibodies

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Additionally we are shipping Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Kits (39) and Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHRNA1 1134 P02708
CHRNA1 79557 P25108
CHRNA1 11435 P04756
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Top anti-Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CHRNA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Mouse Un-conjugated IF, WB Western blot analysis of Acetylcholine Receptor alpha on BC3H1 lysate.... BC3H1 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB Anti-Nicotinic Acetylcholine Receptor alpha 1 antibody, Western blotti... 100 μg Log in to see 4 to 6 Days
$200.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of CHRNA1 staining in human prostate canc... Western blot analysis of CHRNA1 expression in HeLa (A), MCF7 (B), mous... 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with... 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 8 to 10 Days
$793.83
Details

CHRNA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Rat (Rattus) , , ,
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Mouse (Murine) , , ,
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Top referenced anti-Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Antibodies

  1. Mouse (Murine) Monoclonal CHRNA1 Primary Antibody for IF, WB - ABIN968298 : Garchon, Djabiri, Viard, Gajdos, Bach: Involvement of human muscle acetylcholine receptor alpha-subunit gene (CHRNA) in susceptibility to myasthenia gravis. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 5 references for ABIN968298

  2. Cow (Bovine) Polyclonal CHRNA1 Primary Antibody for WB - ABIN2776079 : Webster, Brydson, Croxen, Newsom-Davis, Vincent, Beeson: Mutation in the AChR ion channel gate underlies a fast channel congenital myasthenic syndrome. in Neurology 2004 (PubMed)

More Antibodies against Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Interaction Partners

Human Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) interaction partners

  1. Cholesterol and CAV-1 (show CAV1 Antibodies) modulate the function and dynamics of the slow channel congenital myasthenia syndrome alphaC418W nicotinic acetylcholine receptor mutation.

  2. nicotine contributes to the progression and erlotinib-resistance of the NSCLC xenograft model via the cooperation between nAChR (show CHRNA4 Antibodies) and EGFR (show EGFR Antibodies).

  3. show that AON complementary to the 5' splice site of the exon was the most effective at exon skipping of the minigene with causative mutations, as well as endogenous wild-type CHRNA1

  4. The CHRNA1 extracellular domain is an improved protein for use in antigen-specific Myasthenia Gravis therapeutic strategies.

  5. HnRNP L (show HNRNPL Antibodies) and hnRNP (show HNRNPC Antibodies) LL antagonistically modulate PTB (show PTBP1 Antibodies)-mediated splicing suppression of CHRNA1 pre-mRNA.

  6. High expression of CHRNA1 is associated with lung adenocarcinoma after complete resection.

  7. No mutations were found in CHRNG (show CHRNG Antibodies), CHRND (show CHRND Antibodies) and CHRNA1 genes of Indian families with Escobar syndrome.

  8. Findings identify a novel lung cancer risk locus on 2q31.1 which correlates with CHRNA1 expression and replicate previous associations on 15q25.1 in African-Americans.

  9. V188 is functionally linked to Y190 in the C-loop and to D200 in beta-strand 10 of the acetylcholine receptor alpha subunit (show POLG Antibodies), which connects to the M1 transmembrane domain

  10. Studies suggest that the receptor nAChRalpha1 is an important regulator of calpain-1 (show CAPN1 Antibodies) activation and inflammation in the chronic hypercholesterolemic nephropathy.

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) interaction partners

  1. This study demonstrates that genes coding for CHRNA1 subunits may contain variants associated with statin-induced ADRs.

  2. Chrna1 was co-purified with nicotinic acetylcholine receptor (AChR) in C2C12 myotubes. In addition, Stau1 (show STAU1 Antibodies) was found to interact with Chrna1 mRNA, and knocking down of Stau1 (show STAU1 Antibodies) by RNAi resulted in defective AChR clustering.

  3. These results suggest that in skeletal muscle cells, neural activity reduces the molar ratio of YB-1 (show YBX1 Antibodies) relative to its binding AChR alpha mRNA, leading to an increase of ribosome binding to the mRNA, and thus activating translation.

  4. Chrna1 could be the first transcriptional target of atonal homolog 1 in the inner ear

  5. These data identify caveolin-3 (show CAV3 Antibodies) as a critical component of the signaling machinery that drives nicotinic acetylcholine receptor clustering and controls neuromuscular junction function.

  6. HDAC4 (show HDAC5 Antibodies) is a neural activity-regulated deacetylase and a key signaling component that relays neural activity to the muscle transcriptional machinery through Dach2 (show DACH2 Antibodies), myogenin (show MYOG Antibodies), and nAChR (show CHRNA4 Antibodies)

  7. In S269I, mutant the peak-current amplitude decreases along trains of nearly saturating ACh (show FGFR3 Antibodies) pulses delivered at physiologically relevant frequencies, consistent with enhanced entry into desensitization in congenital myasthenic syndrome.

  8. In this mouse experiemntal myasthenia gravis study demonstrated that Acetylcholine receptor-alpha1 subunit expression was increase with varying disease severity.

Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) Antigen Profile

Protein Summary

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with CHRNA1

  • acetylcholine receptor alpha subunit (ACHR) antibody
  • cholinergic receptor, nicotinic, alpha 1 (muscle) (CHRNA1) antibody
  • cholinergic receptor, nicotinic, alpha 1 (muscle) (Chrna1) antibody
  • cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) (Chrna1) antibody
  • Achr-1 antibody
  • ACHRA antibody
  • ACHRD antibody
  • Acra antibody
  • AI385656 antibody
  • AI608266 antibody
  • CHRNA antibody
  • CHRNA1 antibody
  • CMS2A antibody
  • FCCMS antibody
  • NACHRA1 antibody
  • SCCMS antibody

Protein level used designations for CHRNA1

acetylcholine receptor subunit alpha , acetylcholine receptor, nicotinic, alpha 1 (muscle) , cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) , muscle nicotinic acetylcholine receptor , nicotinic acetylcholine receptor alpha subunit , nicotinic cholinergic receptor alpha 1 , muscle nicotinic acetylcholine receptor alpha-su exon P4 , nachr alpha-subunit , nicotinic acetylcholine recepter alpha-subunit , cholinergic receptor nicotinic alpha polypeptide 1 , alpha-1 subunit, nicotinic acetylcholine receptor , nicotinic cholinergic receptor alpha polypeptide 1

GENE ID SPECIES
751106 Felis catus
1134 Homo sapiens
403757 Canis lupus familiaris
338070 Bos taurus
79557 Rattus norvegicus
395608 Gallus gallus
396587 Sus scrofa
101110120 Ovis aries
11435 Mus musculus
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