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Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) ELISA Kits

CHRNA4 encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. Additionally we are shipping Cholinergic Receptor, Nicotinic, alpha 4 Antibodies (54) and Cholinergic Receptor, Nicotinic, alpha 4 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CHRNA4 1137 P43681
CHRNA4 25590 P09483
CHRNA4 11438 O70174
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Top Cholinergic Receptor, Nicotinic, alpha 4 ELISA Kits at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Rat
96 Tests Log in to see 11 to 13 Days
$875.60
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Chicken
96 Tests Log in to see 11 to 13 Days
$1,095.60
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Human
96 Tests Log in to see 11 to 13 Days
$875.60
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More ELISA Kits for Cholinergic Receptor, Nicotinic, alpha 4 Interaction Partners

Zebrafish Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) interaction partners

  1. and chrna4 RNAs were each expressed in a unique pattern, which changed during development

Human Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) interaction partners

  1. Results provide further evidence that common synonymous CHRNA4 exon 5 SNPs affect cognitive processes and suggest that they also play a role in the auditory system.

  2. Common CHRNA4 variant with important regulatory properties that contributes to nicotine dependence and smoking-related consequences was identified.

  3. the identity of subunits neighboring the otherwise equivalent alpha4(+)/(-)beta2 agonist sites modifies their contributions to nAChR activation and E-loop residues are an important contributor to this neighbor effect

  4. findings demonstrate that the complementary alleles of the CHRNA4 exon 5 haplotype differ with respect to mRNA stability, codon usage and agonist sensitivity

  5. CHRNA4 rs1044396 CT/TT genotype is related to cigarette smoking in Parkinson's disease patients.

  6. study demonstrated that genetic variation of CHRNA4 (rs1044396) increased blink (show TGFb ELISA Kits) rate while watching a video; suggests that differences in sensitivity to acetylcholine because of the genetic variation are associated with individual differences in spontaneous eye blink (show TGFb ELISA Kits) rate

  7. Study investigated whether the rs1044396 polymorphism of the CHRNA4 gene modulates response speed and selective visual attention in the Stroop task, Negative priming task, and Posner-Cuing task in n = 157 healthy participants

  8. Description of a de novo missense mutation in the transmembrane domain M2 segment of CHRNA (show CHRNA1 ELISA Kits)$, c.823A>T, which decreased the surrounding hydrophobicity and slightly altered secondary structure of the protein

  9. Variants in CHRNA4 may contribute to risk of binge drinking in young adults.

  10. There were no effects of CHRNA4 or DAT1 on either facilitation or inhibition of return.

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) interaction partners

  1. The alpha4 nAChR subunit is regulated by protein kinase C epsilon (show PRKCE ELISA Kits) phosphorylation.

  2. neuroinflammation is sufficient to provoke the decrease of a7 and a4b2 nAChRs, Ab42 accumulation and memory impairment in mice and a7(1-208) nAChR-specific antibodies can cause inflammation of the brain with symptoms typical for Alzheimer disease.

  3. Lynx2 and Ly6g6e have roles in intracellular trafficking and allosteric potentiation of alpha4beta2 nAChRs, respectively

  4. The study shows that nAChR alpha4 beta2 sensitizes a MAPK (show MAPK1 ELISA Kits)-linked toxicity pathway on prolonged exposure to ABETA (show APP ELISA Kits) (1-42).

  5. This study has revealed complex effects of Chrna4 deficiency and prenatal nicotine exposure on ventilatory and metabolic interactions and responses to stress.

  6. It indicated that Correlation between nAChalpha4-, 5-HT1A (show HTR1A ELISA Kits)- and 5-HT7 (show HTR7 ELISA Kits)-containing receptors and latencies on day 16 may point to a probable link in extinction mechanisms.

  7. These results question the conclusion that a dominant-negative mechanism would explain the dominance of the mutant L501fsX533 Fz4 (show FZD4 ELISA Kits) allele in the transmission of a form of Familial exudative vitreoretinopathy.

  8. Study demonstrates that chronic pre-exposure to nicotine at a dosing regimen that results in maximal alpha4 nAChR upregulation results in significantly elevated oral nicotine self-administration in a two-bottle choice paradigm in mice

  9. Lynx1 (show LYNX1 ELISA Kits) has a role in shifting alpha4beta2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum

  10. these data indicate that a4-nAChR have an impact on motor output.

Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) Antigen Profile

Antigen Summary

This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with CHRNA4

  • neuronal acetylcholine receptor subunit alpha-4 (CpipJ_CPIJ002434) antibody
  • Neuronal acetylcholine receptor subunit alpha-4-like (LOC100368057) antibody
  • cholinergic receptor, nicotinic, alpha 4 (CHRNA4) antibody
  • neuronal acetylcholine receptor subunit alpha-4-like (LOC100434875) antibody
  • cholinergic receptor, nicotinic, alpha 4 (chrna4) antibody
  • cholinergic receptor, nicotinic, alpha 4 (neuronal) (CHRNA4) antibody
  • cholinergic receptor, nicotinic, alpha 4 (neuronal) (Chrna4) antibody
  • cholinergic receptor, nicotinic, alpha polypeptide 4 (Chrna4) antibody
  • Acra-4 antibody
  • Acra4 antibody
  • BFNC antibody
  • EBN antibody
  • EBN1 antibody
  • ENFL1 antibody
  • NACHR antibody
  • NACHRA4 antibody
  • NACRA4 antibody
  • NARAC antibody

Protein level used designations for CHRNA4

neuronal acetylcholine receptor subunit alpha-4 , Neuronal acetylcholine receptor subunit alpha-4-like , cholinergic receptor, nicotinic, alpha 4 , neuronal acetylcholine receptor subunit alpha-4-like , neuronal nicotinic acetylcholine receptor alpha 4 subunit , alpha-4 subunit, nicotinic acetylcholine receptor , cholinergic receptor, nicotinic, alpha polypeptide 4 , neuronal nicotinic acetylcholine receptor alpha-4 subunit , Neuronal nicotinic acetylcholine receptor alpha 4 subunit , cholinergic receptor, nicotinic, alpha 4 subunit , neuronal acetylcholine receptor alpha-4 subunit , a4 nicotinic receptor , acetylcholine receptor alpha 4 neural , acetylcholine receptor, neuronal, nicotinic, alpha-4 subunit , alpha4 nAChR , alpha4-nAChR

GENE ID SPECIES
6033616 Culex quinquefasciatus
100368057 Saccoglossus kowalevskii
100405714 Callithrix jacchus
100434875 Pongo abelii
537251 Bos taurus
556619 Danio rerio
395606 Gallus gallus
1137 Homo sapiens
25590 Rattus norvegicus
485972 Canis lupus familiaris
469999 Pan troglodytes
11438 Mus musculus
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