Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5) ELISA Kits

The protein encoded by CHRNA5 is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Additionally we are shipping CHRNA5 Antibodies (74) and CHRNA5 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CHRNA5 1138 P30532
Anti-Rat CHRNA5 CHRNA5 25102  
Anti-Mouse CHRNA5 CHRNA5 110835 Q2MKA5
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Top CHRNA5 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.31 ng/mL 0.78 ng/mL - 50 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details

More ELISA Kits for CHRNA5 Interaction Partners

Human Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5) interaction partners

  1. Our present study suggested that rs667282 in CHRNA5-A3 may modify the prognosis of patients with advanced non-small cell lung cancer

  2. our results show that a genomic region with functionally related genes, such as the CHRNA5/CHRNA3/CHRNB4 cluster, is under coordinated regulatory control.

  3. The minor allele increased the risk of COPD (show ARCN1 ELISA Kits) when compared to the population at large. Homozygosity for the risk allele was associated in both cohorts with all-cause mortality, with any type of cancer among the COPD (show ARCN1 ELISA Kits) patients and with the number of pack-years among the male smokers.

  4. The data replicate previous result suggesting CHRNA5 as a candidate gene for chronic obstructive pulmonary disease (COPD (show ARCN1 ELISA Kits)) and rs8040868 as a risk variant for the development of COPD (show ARCN1 ELISA Kits) in the Swedish population.

  5. The results of this study suggests a pleiotropic role of Chr15q25 CHRNA5-CHRNA3-CHRNB4 gene cluster with complex influences in ADHD, tobacco smoking and cognitive performance.

  6. Polymorphisms in the CHRNA5 and NRXN1 (show NRXN1 ELISA Kits) genes, influenced greater consumption of cigarettes in a Mexican Mestizo population.

  7. RP11 (show PRPF31 ELISA Kits)-650L12.2 rs149941240 polymorphism was associated with the risk of colorectal cancer.

  8. We determined that the other patients harbored mutations in genes that have not previously been linked to RTT or other neurodevelopmental syndromes, such as the ankyrin repeat containing protein ANKRD31 or the neuronal acetylcholine receptor subunit alpha-5 (CHRNA5).

  9. quitting smoking is highly beneficial in reducing lung cancer risks for smokers regardless of their CHRNA5 rs16969968 genetic risk status. Smokers with high-risk CHRNA5 genotypes, on average, can largely eliminate their elevated genetic risk for lung cancer by quitting smoking- cutting their risk of lung cancer in half and delaying its onset by 7years for those who develop it.

  10. Study showed that multiple rare, low frequency and common variants in the CHRNA5 gene contribute to the development of nicotine dependence

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5) interaction partners

  1. Chrna5 KO mice did not exhibit high responses to novelty but showed decreased novelty-induced rearing behaviour together with high anxiety. Exposure to high doses of nicotine rescued these phenotypes. Results suggest that altered alpha5*-nAChR (show CHRNA4 ELISA Kits) cholinergic signalling contributes to emotional/behavioural impairments that may be alleviated by nicotine consumption.

  2. These results highlight the involvement of the alpha5 nAChR (show CHRNA4 ELISA Kits) subunit in the development of hyperalgesia, allodynia and inflammation associated with chronic neuropathic and inflammatory pain models.

  3. Overexpression of the genomic cluster CHRNA5/A3/B4 in mice increases somatic signs associated with morphine withdrawal and Knockout of alpha5 gene reduced somatic signs in morphine-treated mice

  4. Data reveal a highly regulated temporal-spatial pattern of alpha5 nAChR (show CHRNA4 ELISA Kits) subunit expression during important periods of lung morphogenesis by FoxA2 (show FOXA2 ELISA Kits).

  5. increased nicotine intake in mice with a null mutation in Chrna5

  6. Polymorphisms located within the Chrna5-Chrna3-Chrnb4 cluster on mouse chromosome 9 were found to co-segregate with alcohol preference, with high-drinking F(2) mice carrying B6 alleles and low-drinking F(2) mice carrying D2 alleles.

CHRNA5 Antigen Profile

Antigen Summary

The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).

Gene names and symbols associated with CHRNA5

  • cholinergic receptor, nicotinic, alpha 5 (chrna5) antibody
  • cholinergic receptor nicotinic alpha 5 subunit (CHRNA5) antibody
  • cholinergic receptor nicotinic alpha 5 subunit L homeolog (chrna5.L) antibody
  • cholinergic receptor nicotinic alpha 5 subunit (Chrna5) antibody
  • cholinergic receptor, nicotinic, alpha polypeptide 5 (Chrna5) antibody
  • Acra-5 antibody
  • Acra5 antibody
  • LNCR2 antibody
  • zgc:110642 antibody

Protein level used designations for CHRNA5

neuronal acetylcholine receptor subunit alpha-5 , cholinergic receptor, nicotinic, alpha polypeptide 5 , Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5 , acetylcholine receptor, nicotinic, alpha 5 (neuronal) , neuronal nicotinic acetylcholine receptor, alpha5 subunit , acetylcholine receptor alpha 5 , cholinergic receptor neuronal nicotinic alpha protein 5 , nicotinic acetylcholine receptor alpha5 subunit

GENE ID SPECIES
550584 Danio rerio
282177 Bos taurus
1138 Homo sapiens
446384 Xenopus laevis
386577 Gallus gallus
482112 Canis lupus familiaris
25102 Rattus norvegicus
619369 Pan troglodytes
110835 Mus musculus
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