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Cholinergic Receptor, Nicotinic, alpha 7 (CHRNA7) ELISA Kits

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Additionally we are shipping and many more products for this protein.

list all ELISA KIts Gene Name GeneID
CHRNA7  
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Top CHRNA7 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.112 ng/mL 0.313-20 ng/mL 96 Tests Log in to see 5 to 9 Days
$1,030.69
Details

More ELISA Kits for CHRNA7 Interaction Partners

Cow (Bovine) Cholinergic Receptor, Nicotinic, alpha 7 (CHRNA7) interaction partners

  1. We conclude that residues in the M2 segment and flanking regions contribute to the unusual properties of the CHRNA7 receptor

  2. Loop 3 and its docking to the alpha-helix is an important requirement for receptor assembly of the alpha7 nicotinic receptor.

  3. a network of interactions formed by residues Lys (show LYZ ELISA Kits)-46, Asp (show ASIP ELISA Kits)-128, Asp (show ASIP ELISA Kits)-135, Asp (show ASIP ELISA Kits)-266, and possibly others appears to link agonist binding to channel gating

CHRNA7 Antigen Profile

Antigen Summary

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with CHRNA7

  • neuronal acetylcholine receptor subunit alpha-7 (LOC100374356) antibody
  • neuronal acetylcholine receptor subunit alpha-7-like (LOC100385253) antibody
  • neuronal acetylcholine receptor subunit alpha-7-like (LOC100401878) antibody
  • cholinergic receptor, nicotinic, alpha 7 (CHRNA7) antibody
  • cholinergic receptor, nicotinic, alpha polypeptide 7 (chrna7) antibody
  • cholinergic receptor, nicotinic, alpha 7 (LOC100228395) antibody
  • dZ70B1.1 antibody

Protein level used designations for CHRNA7

neuronal acetylcholine receptor subunit alpha-7 , neuronal acetylcholine receptor subunit alpha-7-like , cholinergic receptor, nicotinic, alpha 7 , alpha 7 nicotinic acetylcholine receptor , cholinergic receptor, nicotinic, alpha polypeptide 7

GENE ID SPECIES
100374356 Saccoglossus kowalevskii
100385253 Callithrix jacchus
100401878 Callithrix jacchus
100456533 Pongo abelii
394199 Danio rerio
100228395 Taeniopygia guttata
282178 Bos taurus
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