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Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) Proteins (CHRNA9)

CHRNA9 is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. Additionally we are shipping CHRNA9 Antibodies (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHRNA9 55584 Q9UGM1
Rat CHRNA9 CHRNA9 65024 P43144
Mouse CHRNA9 CHRNA9 231252  
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Top CHRNA9 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CHRNA9 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9) Interaction Partners

Human Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9) interaction partners

  1. The rare variants in CHRNA9 were significantly associated with smoking status.

  2. Our findings support a significant interaction effect existing between the CHRNA9 gene and smoking exposure on the risk of breast cancer development.

  3. CHRNA9 polymorphisms are associated with non-small cell lung cancer.

  4. Thia case-control analysis revealed that an increased risk of lung cancer is associated with two SNPs in CHRNA9, rs56159866 and rs6819385.

  5. Data suggest that the biologic activities of Alpha9 nicotinic receptor (CHRNA9) may be regulated at the splicing level, and genetic polymorphisms in CHRNA9 affecting protein levels, amino acid sequence and RNA splicing may influence the risk for lung cancer.

  6. A two order of magnitude species difference in potency of alpha-conotoxin RgIA is reported for rat versus human alpha9alpha10 nAChR (show CHRNA4 Proteins).

  7. Estrogen receptor-alpha (show ESR1 Proteins) plays a central role in mediating alpha9-nAChR (show CHRNA4 Proteins) gene up-regulation in response to either nicotine or estradiol stimulation.

  8. Significant increases in the alpha9-nAChR (show CHRNA4 Proteins) mRNA and protein levels in MCF-7 cells were detected 6 h after nicotine treatment. Nicotine- and estrogen-induced alpha9-nicotinic acetylcholine receptor upregulation was blocked by (-)-epigallocatechin-3-gallate.

  9. These results suggest that alpha9-nAChR (show CHRNA4 Proteins)-mediated cyclin D3 (show CCND3 Proteins) overexpression is important for nicotine-induced transformation of normal human breast epithelial cells.

  10. The alpha9-nAChR (show CHRNA4 Proteins) is important for nicotine-induced transformation of normal human breast epithelial cells. Results imply that receptor-mediated carcinogenic signals play a decisive role in biological functions related to human breast cancer development.

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9) interaction partners

  1. alpha9-nAChR (show CHRNA4 Proteins) KO mice showed normal responses to acute noxious thermal and mechanical stimuli, and developed normal chronic cold and mechanical allodynia in inflammatory and nerve injury pain models.

  2. Inhibition of N-type Ca(2 (show CA2 Proteins)+) channel channels by Vc1.1 and RgIA conotoxins is not mediated by the expression of alpha9 nAChRs in dorsal root ganglia neurons.

  3. Relative to their wild-type littermates, Chrna9(L9'T/L9'T) mice showed less permanent hearing loss following exposure to intense noise. Thus, a point mutation designed to alter alpha9alpha10 receptor gating has provided an animal model.

  4. In nAChR (show CHRNA4 Proteins) alpha9 null mice there is premature, effusive innervation to the synaptic pole of outer hair cells coinciding with delayed expression of cell adhesion proteins.Collapse of ectopic innervation coincides with age-related hyperexpression pattern.

  5. description of the role of alpha9 nAChR (show CHRNA4 Proteins) subunit in the development of the olivocochlear system and efferent function

CHRNA9 Protein Profile

Protein Summary

This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.

Gene names and symbols associated with CHRNA9

  • cholinergic receptor, nicotinic, alpha 9 (CHRNA9)
  • cholinergic receptor, nicotinic, alpha 9 (neuronal) (CHRNA9)
  • cholinergic receptor, nicotinic, alpha 9 (neuronal) (Chrna9)
  • cholinergic receptor, nicotinic, alpha polypeptide 9 (Chrna9)
  • 2410015I05Rik protein
  • Acra9 protein
  • EG666827 protein
  • Gm8311 protein
  • HSA243342 protein
  • NACHRA9 protein

Protein level used designations for CHRNA9

NACHR alpha-9 , cholinergic receptor, nicotinic, alpha polypeptide 9 , neuronal acetylcholine receptor subunit alpha-9 , nicotinic acetylcholine receptor subunit alpha-9 , NACHR alpha 9 , acetylcholine receptor, neuronal nicotinic, alpha-9 subunit , neuronal acetylcholine receptor protein, alpha-9 subunit , nicotinic acetylcholine receptor subunit alpha 9 , acetylcholine receptor alpha 9 subunit (nAChR) , cholinergic receptor, nicotinic, alpha 9

GENE ID SPECIES
395522 Gallus gallus
521876 Bos taurus
55584 Homo sapiens
488832 Canis lupus familiaris
65024 Rattus norvegicus
100513414 Sus scrofa
231252 Mus musculus
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